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7 Feb 2026
BMRC
Singapore Institute of Food and Biotechnology Innovation
Expanding biotechnological applications of Yarrowia lipolytica: Key advances in the past decade
Benedict Ryan Lukito,
Naazneen Sofeo,
Hui Jean Lim,
Muhammad Harith bin Mohammad Taufik,
Prakash Arumugam,
Aiqun Yu,
Adison Wong
Biotechnology Advances
3 Sep 2025
BMRC
Singapore Institute of Food and Biotechnology Innovation
Mutations in the Substrate-Binding Pocket of DiacylGlycerol Acyltransferase Alter the Fatty Acid Composition of Triacylglycerides in Yeast
Nazreen V. M. Abdul Muthaliff,
Nur Eka Fitriani,
Derek Smith,
Jing Sen Ong,
Lay Kien Yang,
Coleen Toledo Busran,
Aaron Thong,
Prakash Arumugam,
Naazneen Sofeo
ACS Synthetic Biology
8 Jan 2024
BMRC
Singapore Institute of Food and Biotechnology Innovation
Sustainable production of lipids from cocoa fatty acid distillate fermentation driven by adaptive evolution in Yarrowia lipolytica
Naazneen Sofeo,
Min Gin Toi,
En Qi Grace Ee,
Jing Yang Ng,
Coleen Toledo Busran,
Benedict Ryan Lukito,
Aaron Thong,
Christian Hermansen,
Eric Charles Peterson,
Renata Glitsos,
Prakash Arumugam
Bioresource Technology
11 Jan 2021
BMRC
Bioinformatics Institute
Identification of pathways modulating vemurafenib resistance in melanoma cells via a genome-wide CRISPR/Cas9 screen
Corinna Jie Hui Goh,
Jin Huei Wong,
Chadi El Farran,
Ban Xiong Tan,
Cynthia R. Coffill,
Yuin-Hain Loh,
David Lane,
Prakash Arumugam
G3: Genes | Genomes | Genetics
11 May 2020
BMRC
Bioinformatics Institute
Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability
Srinivasaraghavan Kannan,
Pietro G. A. Aronica,
Simon Ng,
Dawn Thean Gek Lian,
Yuri Frosi,
Sharon Chee,
Shimin Jiang,
Tsz Ying Yuen,
Ahmad Sadruddin,
Hung Yi Kristal Kaan,
Arun Chandramohan,
Yi Han,
Jin Huei Wong,
Yaw Sing Tan,
Zi Wei Chang,
Fernando Jose Ferrer-Gago,
Prakash Arumugam,
Shiying Chen,
Laurent Claude Stephane Renia,
Christopher J. Brown,
Charles W. Johannes,
Brian Henry,
David P. Lane,
Tomi K Sawyer,
Chandra S. Verma,
Anthony William Patridge
Chemical Science
10 Jun 2019
BMRC
Bioinformatics Institute
Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin
Jin Huei Wong,
Mohammad Alfatah,
Kiat Whye Kong,
Shawn Hoon,
Wan Lin Yeo,
Kuan Chieh Ching,
Corinna Jie Hui Goh,
Mingzi M. Zhang,
Yee Hwee Lim,
Fong Tian Wong,
Prakash Arumugam
PLOS ONE
14 May 2019
BMRC
Bioinformatics Institute
Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723
Swati Sinha,
Choy-Eng Nge,
Chung Yan Leong,
Veronica Ng,
Sharon Crasta,
Mohammad Alfatah,
Falicia Goh,
Kia-Ngee Low,
Huibin Zhang,
Prakash Arumugam,
Alexander Lezhava,
Swaine L. Chen,
Yoganathan Kanagasundaram,
Siew Bee Ng,
Frank Eisenhaber,
Birgit Eisenhaber
BMC Genomics
15 Apr 2019
BMRC
Bioinformatics Institute
Chemical-genetic interaction landscape of mono-(2-ethylhexyl)-phthalate using chemogenomic profiling in yeast
Mohammad Alfatah,
Jin Huei Wong,
Kiat Whye Kong,
Felix Utama,
Shawn Hoon,
Prakash Arumugam
Chemosphere
9 Mar 2018
Others
Experimental Drug Development Centre
Structure-activity relationship studies of ultra-short peptides with potent activities against fluconazole-resistant Candida albicans
Shawn Hoon,
Siew Mei Samantha Ng,
Jia Mao Yap,
Qiu Ying Lau,
Fui Mee Ng,
Esther Ong,
Timothy Barkham,
Jeanette Teo,
Alfatah Mohammad,
Kiat Whye Kong,
Prakash Arumugam,
Jeffrey Hill,
Brian Chia
European Journal of Medicinal Chemistry
9 Nov 2017
BMRC
p53 Laboratory
A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein–protein interactions identifies a novel putative Mdm2-binding site in p53
Jin Huei Wong,
Mohammad Alfatah,
Mei Fang Sin,
Hong May Sim,
Chandra S. Verma,
David P. Lane,
Prakash Arumugam
BMC Biology
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