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Publication date Communities Collections Article title Author(s) Journal/Conference
29 Sep 2020 BMRC Bioinformatics Institute Structural Modelling of the Lumenal Domain of Human GPAA1, the Metallo-Peptide Synthetase Subunit of the Transamidase Complex, Reveals Zinc-Binding Mode and Two Flaps Surrounding the Active Site Tran-To Su Su, Swati Sinha, Birgit Eisenhaber, Frank Eisenhaber Biology Direct
19 Mar 2020 BMRC Bioinformatics Institute Identification and engineering of 32 membered antifungal macrolactone notonesomycins Falicia Goh, Mingzi M. Zhang, Tian Ru Lim, Kia Ngee Low, Choy Eng Nge, Elena Heng, Wan Lin Yeo, Fernanda L. Sirota, Sharon Crasta, Zann Tan, Veronica Ng, Chung Yan Leong, Hubin Zhang, Alexander Lezhava, Swaine L. Chen, Shawn S. Hoon, Frank Eisenhaber, Birgit Eisenhaber, Yoganathan Kanagasundaram, Fong T. Wong, Siew Bee Ng Microbial Cell Factories
1 Jun 2019 BMRC Bioinformatics Institute Hypocrisy Around Medical Patient Data: Issues of Access for Biomedical Research, Data Quality, Usefulness for the Purpose and Omics Data as Game Changer Erwin Tantoso, Wing-Cheong Wong, Wei Hong Tay, Joanne Lee, Swati Sinha, Birgit Eisenhaber, Frank Eisenhaber Asian Bioethics Review
14 May 2019 BMRC Bioinformatics Institute Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723 Swati Sinha, Choy-Eng Nge, Chung Yan Leong, Veronica Ng, Sharon Crasta, Mohammad Alfatah, Falicia Goh, Kia-Ngee Low, Huibin Zhang, Prakash Arumugam, Alexander Lezhava, Swaine L. Chen, Yoganathan Kanagasundaram, Siew Bee Ng, Frank Eisenhaber, Birgit Eisenhaber BMC Genomics
30 Apr 2019 BMRC Bioinformatics Institute Effect of the additional cysteine 503 of vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit F (AhpF) and the mechanism of AhpF and subunit C assembling Yew Kwang Toh, Joon Shin, Asha Manikkoth Balakrishna, Neelagandan Kamariah, Ardina Gruber, Frank Eisenhaber, Birgit Eisenhaber, Gerhard Gruber Free Radical Biology and Medicine
30 Oct 2018 BMRC Bioinformatics Institute Darkness in the Human Gene and Protein Function Space: Widely Modest or Absent Illumination by the Life Science Literature and the Trend for Fewer Protein Function Discoveries Since 2000 Swati Sinha, Birgit Eisenhaber, Lars Juhl Jensen, Bharata Kalbuaji, Frank Eisenhaber Proteomics
20 Sep 2018 BMRC Bioinformatics Institute Molecular mechanism of the Escherichia coli AhpC in the function of a chaperone under heat-shock conditions Neelagandan Kamariah, Birgit Eisenhaber, Frank Eisenhaber, Gerhard Gruber Scientific Reports
21 May 2018 BMRC Bioinformatics Institute Isolation and Identification of an Anthracimycin Analogue from Nocardiopsis kunsanensis, a Halophile from a Saltern, by Genomic Mining Strategy Fernanda L. Sirota, Falicia Goh, Kia-Ngee Low, Lay-Kien Yang, Sharon C. Crasta, Birgit Eisenhaber, Frank Eisenhaber, Yoganathan Kanagasundaram, Siew Bee Ng Journal of Genomics
21 May 2018 BMRC Bioinformatics Institute Isolation and Identification of an Anthracimycin Analogue from Nocardiopsis kunsanensis, a Halophile from a Saltern, by Genomic Mining Strategy Fernanda L. Sirota, Falicia Goh, Kia-Ngee Low, Lay-Kien Yang, Sharon C. Crasta, Birgit Eisenhaber, Frank Eisenhaber, Yoganathan Kanagasundaram, Siew Bee Ng Journal of Genomics
15 May 2018 BMRC Bioinformatics Institute Function of a membrane-embedded domain evolutionarily multiplied in the GPI lipid anchor pathway proteins PIG-B, PIG-M, PIG-U, PIG-W, PIG-V, and PIG-Z. Birgit Eisenhaber, Swati Sinha, Wing-Cheong Wong, Frank Eisenhaber Cell Cycle
21 Feb 2018 BMRC Bioinformatics Institute Active site C P -loop dynamics modulate substrate binding, catalysis, oligomerization, stability, over-oxidation and recycling of 2-Cys Peroxiredoxins Neelagandan Kamariah, Birgit Eisenhaber, Frank Eisenhaber, Gerhard Gruber Free Radical Biology and Medicine
8 Feb 2017 BMRC Bioinformatics Institute Discovery of a novel splice variant of Fcar (CD89) unravels sequence segments necessary for efficient secretion: A story of bad signal peptides and good ones that nevertheless do not make it Wai-Heng Lua, Wei-Li Ling, Chinh Tran-To Su, Joshua Yi Yeo, Chandra S. Verma, Birgit Eisenhaber, Frank Eisenhaber, Samuel Ken-En Gan Cell Cycle
29 Nov 2016 BMRC Bioinformatics Institute xHMMER3x2: Utilizing HMMER3’s speed and HMMER2’s sensitivity and specificity in the glocal alignment mode for improved large-scale protein domain annotation Choon-Kong Yap, Birgit Eisenhaber, Frank Eisenhaber, Wing-Cheong Wong Biology Direct
28 Nov 2016 BMRC Bioinformatics Institute Transition steps in peroxide reduction and a molecular switch for peroxide robustness of prokaryotic peroxiredoxins Neelagandan Kamariah, Mun Foong Sek, Birgit Eisenhaber, Frank Eisenhaber, Gerhard Gruber Scientific Reports
15 Sep 2016 BMRC Bioinformatics Institute A Reversible Association between Smc Coiled Coils Is Regulated by Lysine Acetylation and Is Required for Cohesin Association with the DNA Irina Kulemzina, Keven Ang, Xiaodan Zhao, Jun-Thing Teh, Vikash Verma, Sasikala Suranthran, Alap P. Chavda, Roland G. Huber, Birgit Eisenhaber, Frank Eisenhaber, Jie Yan, Dmitri Ivanov Molecular Cell
24 Sep 2015 BMRC Bioinformatics Institute NMR studies reveal a novel grab and release mechanism for efficient catalysis of the bacterial 2-Cys peroxiredoxin machinery Wilson Nartey, Sandip Basak, Neelagandan Kamariah, Malathy S. S. Manimekalai, Scott Robson, Gerhard Wagner, Birgit Eisenhaber, Frank Eisenhaber, Gerhard Gruber FEBS Journal
23 Oct 2013 BMRC Bioinformatics Institute Powerful Sequence Similarity Search Methods and In-Depth Manual Analyses Can Identify Remote Homologs in Many Apparently “Orphan” Viral Proteins Durga B. Kuchibhatla, Westley A. Sherman, Betty Y. W. Chung, Shelley Cook, Georg Schneider, Birgit Eisenhaber, David G. Karlin Journal of Virology
10 Jan 2013 BMRC Bioinformatics Institute How bioinformatics influences health informatics: usage of biomolecular sequences, expression profiles and automated microscopic image analyses for clinical needs and public health Hwee Kuan Lee, Sebastian Maurer-Stroh, Maria Judit Molnár, Sandor Pongor, Birgit Eisenhaber, Frank Eisenhaber, Vladimir Kuznetsov Health Information Science and Systems