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16 Jan 2021
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BMRC
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Molecular Engineering Laboratory
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CRISPR-Cas strategies for natural product discovery and engineering in actinomycetes
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Elena Heng,
Lee Ling Tan,
Mingzi M. Zhang,
Fong Tian Wong
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Process Biochemistry
|
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6 Jan 2020
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BMRC
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Singapore Institute of Food and Biotechnology Innovation
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Biosynthetic engineering of the antifungal, anti‑MRSA auroramycin
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Wan Lin Yeo,
Elena Heng,
Lee Ling Tan,
Yi Wee Lim,
Kuan Chieh Ching,
De‐Juin Tsai,
Yi Wun Jhang,
Tsai‐Ling Lauderdale,
Kak‐Shan Shia,
Huimin Zhao,
Ee Lui Ang,
Mingzi Zhang,
Yee Hwee Lim,
Fong Tian Wong
|
Microbial Cell Factories
|
|
10 Jun 2019
|
BMRC
|
Bioinformatics Institute
|
Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin
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Jin Huei Wong,
Mohammad Alfatah,
Kiat Whye Kong,
Shawn Hoon,
Wan Lin Yeo,
Kuan Chieh Ching,
Corinna Jie Hui Goh,
Mingzi M. Zhang,
Yee Hwee Lim,
Fong Tian Wong,
Prakash Arumugam
|
PLOS ONE
|
|
15 May 2019
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BMRC
|
Singapore Institute of Food and Biotechnology Innovation
|
Characterization of Cas proteins for CRISPR‐Cas editing in streptomycetes
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Wan Lin Yeo,
Elena Heng,
Lee Ling Tan,
Yi Wee Lim,
Yee Hwee Lim,
Shawn Hoon,
Huimin Zhao,
Mingzi Zhang,
Fong Tian Wong
|
Biotechnology and Bioengineering
|
|
25 May 2018
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BMRC
|
Singapore Institute of Food and Biotechnology Innovation
|
Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR‐Cas9 Activation
|
Yee Hwee Lim,
Fong Tian Wong,
Wan Lin Yeo,
Kuan Chieh Ching,
Yi Wee Lim,
Elena Heng,
Shuwen Chen,
De‐Juin Tsai,
Tsai‐Ling Lauderdale,
Kak‐Shan Shia,
Ying Swan Ho,
Shawn Hoon,
Ee Lui Ang,
Mingzi Zhang,
Huimin Zhao
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ChemBioChem
|
|
10 Apr 2017
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BMRC
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Singapore Institute of Food and Biotechnology Innovation
|
CRISPR–Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters
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Mingzi Zhang,
Fong Tian Wong,
Yajie Wang,
Shangwen Luo,
Yee Hwee Lim,
Elena Heng,
Wan Lin Yeo,
Ryan E Cobb,
Behnam Enghiad,
Ee Lui Ang,
Huimin Zhao
|
Nature Chemical Biology
|