p53 Laboratory

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Publication date Article title Author(s)
19 Apr 2020 Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks Sara Lundsten, Víctor Agmo Hernández, Lars Gedda, Tina Sarén, Christopher J. Brown, David P. Lane, Katarina Edwards, Marika Nestor
16 Apr 2020 Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2 Anja C. L. Mortensen, Eric Morin, Christopher J. Brown, David P. Lane, Marika Nestor
18 Mar 2020 Methods and Approaches for the Solid-Phase Synthesis of Peptide Alcohols Fernando J. Ferrer-Gago, Li Quan Koh
2 Mar 2020 bioPROTACs as Versatile Modulators of Intracellular Therapeutic Targets Including Proliferating Cell Nuclear Antigen (PCNA) Shuhui Lim, Regina Khoo, Khong Ming Peh, Jinkai Teo, Shih Chieh Chang, Simon Ng, Greg L. Beilhartz, Roman A. Melnyk, Charles W. Johannes, Christopher J. Brown, David P. Lane, Brian Henry, Anthony W. Patridge
18 Dec 2019 How the Other Half Lives: What p53 Does When It Is Not Being a Transcription Factor Teresa Ho, Ban Xiong Tan, David Lane
3 Dec 2019 Transmembrane signaling on a protocell: creation of receptor-enzyme chimeras for immunodetection of specific antibodies and antigens Jiulong Su, Tetsuya Kitaguchi, Yuki Ohmuro-Matsuyama, Theresa Seah, Farid J. Ghadessy, Shawn Hoon, Hiroshi Ueda
1 Dec 2019 High Intracellular Stability of the Spidroin N-terminal Domain in Spite of Abundant Amyloidogenic Segments Revealed by In-Cell Hydrogen/Deuterium Exchange Mass Spectrometry Margit Kaldmäe, Axel Leppert, Gefei Chen, Medoune Sarr, Cagla Sahin, Kerstin Nordling, Nina Kronqvist, Marta Gonzalvo-Ulla, Nicolas Fritz, Axel Abelein, Sonia Laίn, Henrik Biverstal, Hans Jornvall, David P. Lane, Anna Rising, Jan Johansson, Michael Landreh
19 Sep 2019 The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells Anja Charlotte Lundgren Mortensen, Diana Spiegelberg, Christopher John Brown, David Philip Lane, Marika Nestor
30 May 2019 Stereoisomerism of Stapled Peptide Inhibitors of the p53-Mdm2 Interaction: An Assessment of Synthetic Strategies and Activity Profiles Tsz Ying Yuen, Christopher J. Brown, Yuezhen Xue, Yaw Sing Tan, Fernando J. Ferrer Gago, Xue Er Lee, Jin Yong Neo, Dawn Thean, Hung Yi Kristal Kaan, Anthony W. Partridge, Chandra S. Verma, David P. Lane, Charles W. Johannes
22 May 2019 Monitoring Flux in Signalling Pathways Through Measurements of 4EBP1-mediated eIF4F Complex Assembly Yuri Frosi, Rachael Usher, Dawn Thean Gek Lian, David P. Lane, Christopher J. Brown