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13 Aug 2018 BMRC Experimental Drug Development Centre Designing an ultra-short antibacterial peptide with potent activity against Mupirocin-resistant MRSA. Giovinna Arfan, Chu Yang Fann Ong, Siew Mei Samantha Ng, Qiu Ying Lau, Fui Mee Ng, Esther Hong Qian Ong, Jeffrey Hill, C. S. Brian Chia Chemical Biology & Drug Design
5 Jul 2018 BMRC Experimental Drug Development Centre Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide Bee Hui Liu, Chacko Jobichen, Cheng San Brian Chia, Tim Hon Man Chan, Jing Ping Tang, Theodora Chung, Jia Li, Anders Poulsen, Alvin W. Hung, Xiaoying Koh-Stenta, Yaw Sing Tan, Chandra S. Verma, Hong Kee Tan, Chan-shuo Wu, Feng Li, Jeffrey Hill, Joma Joy, Henry Yang, Li Chai, J. Sivaraman, Daniel G. Tenen PNAS
5 Jul 2018 BMRC Bioinformatics Institute Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide Bee Hui Liu, Chacko Jobichen, C. S. Brian Chia, Tim Hon Man Chan, Jing Ping Tang, Theodora X. Y. Chung, Jia Li, Anders Poulsen, Alvin W. Hung, Xiaoying Koh-Stenta, Yaw Sing Tan, Chandra S. Verma, Hong Kee Tan, Chan-shuo Wu, Feng Li, Jeffrey Hill, Joma Joy, Henry Yang, Li Chai, J. Sivaraman, Daniel G. Tenen Proceedings of the National Academy of Sciences
11 May 2018 BMRC Bioinformatics Institute Elucidating the bactericidal mechanism of action of the linear antimicrobial tetrapeptide BRBR-NH2 Qiu Ying Lau, Jianguo Li, Marc-Antoine Sani, Sheetal Sinha, Yan Li, Fui Mee Ng, CongBao Kang, Surajit Bhattacharjya, Frances Separovic, Chandra Verma, Cheng San Brian Chia Biochimica et Biophysica Acta (BBA) - Biomembranes
9 Mar 2018 BMRC Experimental Drug Development Centre Structure-activity relationship studies of ultra-short peptides with potent activities against fluconazole-resistant Candida albicans Shawn Hoon, Siew Mei Samantha Ng, Jia Mao Yap, Qiu Ying Lau, Fui Mee Ng, Esther Ong, Timothy Barkham, Jeanette Teo, Alfatah Mohammad, Kiat Whye Kong, Prakash Arumugam, Jeffrey Hill, Brian Chia European Journal of Medicinal Chemistry
22 Jan 2018 BMRC Experimental Drug Development Centre Identification of an ultra-short peptide with potent Pseudomonas aeruginosa activity for development as a topical antibacterial agent Roland Jureen, Jeffrey Hill, Cheng San Brian Chia, Shu Wei Teo, Yaqing Elena Yong, Siew Mei Samantha Ng, Fui Mee Ng, Jeanette Teo International Journal of Peptide Research and Therapeutics
10 Oct 2017 BMRC Experimental Drug Development Centre Repurposing Zidovudine in combination with Tigecycline for treating carbapenem-resistant Enterobacteriaceae infections Jaron Sioson, Jia Mao Yap, Fui Mee Ng, Vivian Ching, Jeanette Teo, Roland Jureen, Jeffrey Hill, Brian Chia, Siew Mei Samantha Ng European Journal of Clinical Microbiology and Infectious Diseases
11 Jul 2017 BMRC Experimental Drug Development Centre Preliminary investigations into developing all-D Omiganan for treating Mupirocin-resistant MRSA skin infections Siew Mei Samantha Ng, Shu Wei Teo, Yaqing Elena Yong, Fui Mee Ng, Qiu Ying Lau, Roland Jureen, Jeffrey Hill, Cheng San Brian Chia Chemical Biology and Drug Design
4 Feb 2017 BMRC Experimental Drug Development Centre Screening for a Potent Antibacterial Peptide to Treat Mupirocin- Resistant MRSA Skin Infections Siew Mei Samantha Ng, Hui Si Vivian Ching, GuiFang Xu, Fui Mee Ng, Esther H. Q. Ong, Qiu Ying Lau, Roland Jureen, Jeffrey Hill, C. S. Brian Chia International Journal of Peptide Research and Therapeutics
19 Jan 2017 BMRC Experimental Drug Development Centre Antifungal peptides: a potential new class of antifungals for treating vulvovaginal candidiasis caused by fluconazole-resistant Candida albicans Yi Yong Alvin Yap, Timothy Barkham, Jin Wei Darryl Cheong, Fui Mee Ng, Qiu Ying Lau, Siew Mei Samantha Ng, Jeanette Woon Pei Teo, Jeffrey Hill, C. S. Brian Chia Journal of Peptide Science
31 May 2016 BMRC Experimental Drug Development Centre Miniature bovine pancreatic trypsin inhibitors (m-BPTIs) of the West Nile virus NS2B-NS3 protease Anders Poulsen, John Liang Kuan Wee, Fui Mee Ng, Joma Joy, Jeffrey Hill, J. Y. Melgious Ang, C. S. Brian Chia, Huichang Annie Lim Journal of Enzyme Inhibition and Medicinal Chemistry
22 Oct 2015 BMRC Experimental Drug Development Centre Discovery of an ultra-short linear antibacterial tetrapeptide with anti-MRSA activity from a structure-activity relationship study. Alvin Yap, Qiu Ying Lau, Fui Mee Ng, Darryl Cheong, Fion Tan, Roland Jureen, Brian Chia European Journal of Medicinal Chemistry
22 Oct 2015 BMRC Institute of Molecular and Cell Biology Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy Guo-Ying Chen, CongBao Kang, Cheng San Brian Chia, Xuelian Luo, Wanjin Hong, Anders Poulsen, Ajaybabu V. Pobbati, Xiao Han, Alvin W. Hung, Seetoh Weiguang, Nur Huda Structure
9 Oct 2015 BMRC Experimental Drug Development Centre An FDA-drug library screen for compounds with bioactivities against meticillin-resistant Staphylococcus aureus (MRSA). Qiu Ying Lau, Yoke Yan Fion Tan, Vanessa Chai Yin Goh, David Jing Qin Lee, Fui Mee Ng, Esther H. Q. Ong, Jeffrey Hill, Cheng San Brian Chia Antibiotics
24 Jun 2015 BMRC Experimental Drug Development Centre Application of Fragment-Based Drug Discovery against DNA Gyrase B Cheng San Brian Chia, Qiu Ying Lau, Jeffrey Hill, Alvin Hung, Thomas Keller, Siew Wen Then, Nur Huda Ahmad, Ying Lei Wong, Hui Qi Ng, Guo-Ying Chen, Fui Mee Ng, Yih Wan Tan, Anders Poulsen, Wei Guang Seetoh, Grace Lin, CongBao Kang ChemPlusChem
5 May 2015 BMRC Experimental Drug Development Centre Target Mechanism-Based Whole-Cell Screening Identifies Bortezomib as an Inhibitor of Caseinolytic Protease in Mycobacteria Horst Flotow, Jeffrey Hill, Ravikiran Raju, Wilfried Moreira, Grace Ngan, Jian Liang Low, Anders Poulsen, Brian Chia, Melgious Ang, Amelia Yap, Justina Fulwood, Umayal Lakshmanan, Jolander Lim, Audrey Khoo, Eric Rubin, Thomas Dick mBio
20 Mar 2015 BMRC Institute of Molecular and Cell Biology Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2–P4 study Melgious J. Y. Ang, Qiu Ying Lau, Fui Mee Ng, Siew Wen Then, Anders Poulsen, Yuen Kuen Cheong, Zi Xian Ngoh, Yong Wah Tan, Jianhe Peng, Thomas H. Keller, Jeffrey Hill, Justin J. H. Chu, C. S. Brian Chia Journal of Enzyme Inhibition and Medicinal Chemistry
7 Nov 2014 BMRC Experimental Drug Development Centre A Head-to-Head Comparison of the Antimicrobial Activities of 30 Ultra- Short Antimicrobial Peptides Against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans Qiu Ying Lau, Fui Mee Ng, Jeffrey Hill, Brian Chia International Journal of Peptide Research and Therapeutics