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Publication date Communities Collections Article title Author(s) Journal/Conference
13 Oct 2023 BMRC Institute of Molecular and Cell Biology Transcriptional repression by a secondary DNA binding surface of DNA topoisomerase I safeguards against hypertranscription Mei Sheng Lau, Zhenhua Hu, Xiaodan Zhao, Yaw Sing Tan, Jinyue Liu, Hua Huang, Clarisse Jingyi Yeo, Hwei Fen Leong, Oleg V. Grinchuk, Justin Kaixuan Chan, Jie Yan, Wee-Wei Tee Nature Communications
6 Oct 2023 BMRC Bioinformatics Institute Shape complementarity processes for ultrashort-burst sensitive M13–PEG–WS2-powered MCF-7 cancer cell sensors Maria P. Meivita, Shao-Xiang Go, Fitya S. Mozar, Lunna Li, Yaw Sing Tan, Natasa Bajalovic, Desmond K. Loke Nanoscale
12 Jan 2023 BMRC Bioinformatics Institute Success probability of high-affinity DNA aptamer generation by genetic alphabet expansion Michiko Kimoto, Hui Pen Tan, Yaw Sing Tan, Nur Afiqah Binte Mohd Mislan, Ichiro Hirao Philosophical Transactions of the Royal Society B: Biological Sciences
18 Aug 2020 BMRC Bioinformatics Institute Straightforward incorporation of multiple ligand types into molecular dynamics simulations for efficient binding site detection and characterization Yaw Sing Tan, Chandra S Verma Journal of Chemical Theory and Computation
11 May 2020 BMRC Bioinformatics Institute Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability Srinivasaraghavan Kannan, Pietro G. A. Aronica, Simon Ng, Dawn Thean Gek Lian, Yuri Frosi, Sharon Chee, Shimin Jiang, Tsz Ying Yuen, Ahmad Sadruddin, Hung Yi Kristal Kaan, Arun Chandramohan, Yi Han, Jin Huei Wong, Yaw Sing Tan, Zi Wei Chang, Fernando Jose Ferrer-Gago, Prakash Arumugam, Shiying Chen, Laurent Claude Stephane Renia, Christopher J. Brown, Charles W. Johannes, Brian Henry, David P. Lane, Tomi K Sawyer, Chandra S. Verma, Anthony William Patridge Chemical Science
11 Dec 2019 SERC Institute of Chemical and Engineering Sciences Synthesis of chiral alkenyl cyclopropane amino acids for incorporation into stapled peptides Tsz Ying Yuen, Christopher J. Brown, Yaw Sing Tan, Charles W. Johannes The Journal of Organic Chemistry
20 Jun 2019 BMRC Bioinformatics Institute Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties Anthony W. Patridge, Hung Yi Kristal Kaan, Yu-Chi Juang, Ahmad Sadruddin, Shuhui Lim, Christopher J. Brown, Simon Ng, Dawn Thean, Fernando Ferrer, Charles Johannes, Tsz Ying Yuen, Srinivasaraghavan Kannan, Pietro Aronica, Yaw Sing Tan, Mohan R. Praddhan, Chandra S. Verma, Jerome Hochman, Shiying Chen, Hui Wan, Sookhee Ha, Brad Sherbone, David P. Lane, Tomi K. Sawyer Molecules
17 Jun 2019 BMRC Bioinformatics Institute Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides Jiraborrirak Charoenpattarapreeda, Yaw Sing Tan, Jessica Iegre, Stephen J. Walsh, Elaine Fowler, Rohan Eapen, Yuteng Wu, Hannah F. Sore, Chandra S. Verma, Laura Itzhaki, David R. Spring Chemical Communications
30 May 2019 BMRC p53 Laboratory Stereoisomerism of Stapled Peptide Inhibitors of the p53-Mdm2 Interaction: An Assessment of Synthetic Strategies and Activity Profiles Tsz Ying Yuen, Christopher J. Brown, Yuezhen Xue, Yaw Sing Tan, Fernando J. Ferrer Gago, Xue Er Lee, Jin Yong Neo, Dawn Thean, Hung Yi Kristal Kaan, Anthony W. Partridge, Chandra S. Verma, David P. Lane, Charles W. Johannes Chemical Science
30 May 2019 BMRC Bioinformatics Institute Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles Tsz Ying Yuen, Christopher J. Brown, Yuezhen Xue, Yaw Sing Tan, Fernando J. Ferrer Gago, Xue Er Lee, Jin Yong Neo, Dawn Thean, Hung Yi Kristal Kaan, Anthony W. Partridge, Chandra S. Verma, David P. Lane, Charles A. Johannes Chemical Science