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14 Jul 2021
BMRC
Institute of Molecular and Cell Biology
CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity
Ying Yu Liang,
Smaranda Bacanu,
Lekshmy Sreekumar,
Anderson Daniel Ramos,
Lingyun Dai,
Martin Michaelis,
Jindrich Cinatl,
Takahiro Seki,
Yihai Cao,
Cynthia R. Coffill,
David P. Lane,
Nayana Prabhu,
Pär Nordlund
Cell Chemical Biology
11 Jan 2021
BMRC
Bioinformatics Institute
Identification of pathways modulating vemurafenib resistance in melanoma cells via a genome-wide CRISPR/Cas9 screen
Corinna Jie Hui Goh,
Jin Huei Wong,
Chadi El Farran,
Ban Xiong Tan,
Cynthia R. Coffill,
Yuin-Hain Loh,
David Lane,
Prakash Arumugam
G3: Genes | Genomes | Genetics
7 Feb 2017
BMRC
p53 Laboratory
Anatomy of Mdm2 and Mdm4 in evolution
Ban Xiong Tan,
Hoe Peng Liew,
Joy S. Chua,
Farid J. Ghadessy,
Yaw Sing Tan,
David P. Lane,
Cynthia R. Coffill
Journal of Molecular Cell Biology
28 Sep 2016
BMRC
Bioinformatics Institute
Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens
Jia Wei Siau,
Cynthia R. Coffill,
Weiyun Villien Zhang,
Yaw Sing Tan,
Juliane Hundt,
David Lane,
Chandra Verma,
Farid Ghadessy
Scientific Reports
21 Jan 2016
BMRC
Bioinformatics Institute
The p53–Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans
Cynthia R. Coffill,
Alison P. Lee,
Jia Wei Siau,
Sharon M. Chee,
Thomas L. Joseph,
Yaw Sing Tan,
Arumugam Madhumalar,
Boon-Hui Tay,
Sydney Brenner,
Chandra S. Verma,
Farid J. Ghadessy,
Byrappa Venkatesh,
David P. Lane
Genes & Development
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