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8 Nov 2024
SERC
Institute of Sustainability for Chemicals, Energy and Environment
A Machine Learning-Guided Approach to Navigate the Substrate Activity Scope of Galactose Oxidase: Application in the Conversion of Pharmaceutically Relevant Bulky Secondary Alcohols
Shreyas Supekar,
Dillon W. P. Tay,
Wan Lin Yeo,
Kwok Wai Eric Tam,
Ying Sin Koo,
Jie Yang See,
Jhoann M. T. Miyajima,
Sebastian Maurer-Stroh,
Ee Lui Ang,
Yee Hwee Lim,
Hao Fan
ACS Catalysis
23 Sep 2024
SERC
Institute of Sustainability for Chemicals, Energy and Environment
Composite Machine Learning Strategy for Natural Products Taxonomical Classification and Structural Insights
Qisong Xu,
Alan K. X. Tan,
Liangfeng Guo,
Yee Hwee Lim,
Dillon W. P. Tay,
Shi Jun Ang
Digital Discovery
7 Sep 2024
SERC
Institute of Sustainability for Chemicals, Energy and Environment
Tandem mass spectral metabolic profiling of 54 actinobacterial strains and their 459 mutants
Dillon W. P. Tay,
Lee Ling Tan,
Elena Heng,
Nadiah Zulkarnain,
Elaine Jinfeng Chin,
Zann Yi Qi Tan,
Chung Yan Leong,
Veronica Wee Pin Ng,
Lay Kien Yang,
Deborah C. S. Seow,
Yoganathan Kanagasundaram,
Siew Bee Ng,
Yee Hwee Lim,
Fong Tian Wong
Scientific Data
1 Dec 2023
BMRC
Singapore Institute of Food and Biotechnology Innovation
Directed Evolution and Computational Modeling of Galactose Oxidase toward Bulky Benzylic and Alkyl Secondary Alcohols
Wan Lin Yeo,
Dillon W. P. Tay,
Jhoann M.T. Miyajima,
Shreyas Supekar,
Tong Mei Teh,
Jin Xu,
Yee Ling Tan,
Jie Yang See,
Hao Fan,
Sebastian Maurer-Stroh,
Yee Hwee Lim,
Ee Lui Ang
ACS Catalysis
9 Nov 2023
SERC
Institute of Sustainability for Chemicals, Energy and Environment
Expression and engineering of PET-degrading enzymes from Microbispora, Nonomuraea, and Micromonospora
Elaine Tiong,
Ying Sin Koo,
Jiawu Bi,
Lokanand Koduru,
Winston Koh,
Yee Hwee Lim,
Fong Tian Wong
Applied and Environmental Microbiology
11 Aug 2023
BMRC
Bioprocessing Technology Institute
The Engineering, Expression, and Immobilization of Epimerases for D-allulose Production
Jin Hao Tan,
Anqi Chen,
Jiawu Bi,
Yee Hwee Lim,
Fong Tian Wong,
Dave Siak-Wei Ow
International Journal of Molecular Sciences
7 Jul 2023
SERC
Institute of Sustainability for Chemicals, Energy and Environment
Further Characterization of Fungal Halogenase RadH and Its Homologs
GuangRong Peh,
Gregory A. Gunawan,
Terence Tay,
Elaine Tiong,
Lee Ling Tan,
Shimin Jiang,
Yi Ling Goh,
Suming Ye,
Joel Wong,
Christopher J. Brown,
Huimin Zhao,
Ee Lui Ang,
Fong Tian Wong,
Yee Hwee Lim
Biomolecules
19 May 2023
SERC
Institute of Sustainability for Chemicals, Energy and Environment
67 million natural product-like compound database generated via molecular language processing
Dillon W. P. Tay,
Naythan Z. X. Yeo,
Krishnan Adaikkappan,
Yee Hwee Lim,
Shi Jun Ang
Scientific Data
28 Apr 2023
BMRC
Institute of Molecular and Cell Biology
Enhancing armeniaspirols production through multi-level engineering of a native Streptomyces producer
Elena Heng,
Yi Wee Lim,
Chung Yan Leong,
Veronica W. P. Ng,
Siew Bee Ng,
Yee Hwee Lim,
Fong Tian Wong
Microbial Cell Factories
8 Dec 2022
SERC
Institute of Sustainability for Chemicals, Energy and Environment
An improved stereodivergent and practical synthesis of α- and β-pseudouridines
Viktor Barát,
Anqi Chen,
Yee Hwee Lim
Reaction Chemistry & Engineering
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