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11 Jan 2021
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BMRC
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Bioinformatics Institute
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Identification of pathways modulating vemurafenib resistance in melanoma cells via a genome-wide CRISPR/Cas9 screen
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Corinna Jie Hui Goh,
Jin Huei Wong,
Chadi El Farran,
Ban Xiong Tan,
Cynthia R. Coffill,
Yuin-Hain Loh,
David Lane,
Prakash Arumugam
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G3: Genes | Genomes | Genetics
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11 May 2020
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BMRC
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Bioinformatics Institute
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Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability
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Srinivasaraghavan Kannan,
Pietro G. A. Aronica,
Simon Ng,
Dawn Thean Gek Lian,
Yuri Frosi,
Sharon Chee,
Shimin Jiang,
Tsz Ying Yuen,
Ahmad Sadruddin,
Hung Yi Kristal Kaan,
Arun Chandramohan,
Yi Han,
Jin Huei Wong,
Yaw Sing Tan,
Zi Wei Chang,
Fernando Jose Ferrer-Gago,
Prakash Arumugam,
Shiying Chen,
Laurent Claude Stephane Renia,
Christopher J. Brown,
Charles W. Johannes,
Brian Henry,
David P. Lane,
Tomi K Sawyer,
Chandra S. Verma,
Anthony William Patridge
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Chemical Science
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10 Jun 2019
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BMRC
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Bioinformatics Institute
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Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin
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Jin Huei Wong,
Mohammad Alfatah,
Kiat Whye Kong,
Shawn Hoon,
Wan Lin Yeo,
Kuan Chieh Ching,
Corinna Jie Hui Goh,
Mingzi M. Zhang,
Yee Hwee Lim,
Fong Tian Wong,
Prakash Arumugam
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PLOS ONE
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14 May 2019
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BMRC
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Bioinformatics Institute
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Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723
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Swati Sinha,
Choy-Eng Nge,
Chung Yan Leong,
Veronica Ng,
Sharon Crasta,
Mohammad Alfatah,
Falicia Goh,
Kia-Ngee Low,
Huibin Zhang,
Prakash Arumugam,
Alexander Lezhava,
Swaine L. Chen,
Yoganathan Kanagasundaram,
Siew Bee Ng,
Frank Eisenhaber,
Birgit Eisenhaber
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BMC Genomics
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15 Apr 2019
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BMRC
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Bioinformatics Institute
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Chemical-genetic interaction landscape of mono-(2-ethylhexyl)-phthalate using chemogenomic profiling in yeast
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Mohammad Alfatah,
Jin Huei Wong,
Kiat Whye Kong,
Felix Utama,
Shawn Hoon,
Prakash Arumugam
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Chemosphere
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9 Mar 2018
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BMRC
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Experimental Drug Development Centre
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Structure-activity relationship studies of ultra-short peptides with potent activities against fluconazole-resistant Candida albicans
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Shawn Hoon,
Siew Mei Samantha Ng,
Jia Mao Yap,
Qiu Ying Lau,
Fui Mee Ng,
Esther Ong,
Timothy Barkham,
Jeanette Teo,
Alfatah Mohammad,
Kiat Whye Kong,
Prakash Arumugam,
Jeffrey Hill,
Brian Chia
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European Journal of Medicinal Chemistry
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9 Nov 2017
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BMRC
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p53 Laboratory
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A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein–protein interactions identifies a novel putative Mdm2-binding site in p53
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Jin Huei Wong,
Mohammad Alfatah,
Mei Fang Sin,
Hong May Sim,
Chandra S. Verma,
David P. Lane,
Prakash Arumugam
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BMC Biology
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26 Jul 2016
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BMRC
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Bioinformatics Institute
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PP2ACdc55’s role in reductional chromosome segregation during achiasmate meiosis in budding yeast is independent of its FEAR function
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Gary W. Kerr,
Jin Huei Wong,
Prakash Arumugam
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Scientific Reports
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