Experimental Drug Development Centre

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Publication date Article title Author(s)
3 Apr 2026 Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B Donghoon Chung, Yuka Otsuka, Eunjung Kim, Sultan Ullah, Nicole M. Kennedy, Khac Huy Ngo, Jinjoo Kang, Reece Tomlinson, Brian Alejandro, Koji Barnaby, Jeffrey Miller, Justin Shumate, Chwee Fang Teo, Yaw Bia Tan, Che Shin Chew, CongBao Kang, Dahai Luo, Louis Scampavia, Timothy P. Spicer, Thomas D. Bannister
14 Mar 2026 An inactive Zika NS2B-NS3pro protease construct for investigating allosteric inhibitors Khac Huy Ngo, Simon Lattmann, Paulina Duhita Anindita, Chong Wai Liew, Reuben S. Harris, Dahai Luo, CongBao Kang
23 Aug 2025 19F NMR in RNA structural biology: exploring structures, dynamics, and small molecule interactions CongBao Kang
7 Aug 2025 Discovery of an Orally Bioavailable Reversible Covalent SARS-CoV-2 Mpro Inhibitor with Pan-Coronavirus Activity Qian Wen Tan, Subramanyam Vankadara, Jia Yi Fong, Yi Yang See, Nithya Baburajendran, Pearly Shuyi Ng, Weijun Xu, Yee Khoon Yeo, Weiling Wang, Choon Heng Low, Li Hong Tan, Eileen Gui Ju Tay, Yun Xuan Wong, Chuhui Huang, Sandra Sim, Shi Hua Ang, Hannah Hui Min Toh, Juliana Mohammad, Gang Wang, Boping Liu, Shu Ting Tan, Perlyn Zekui Kwek, Monique Danielle Dawson, Qin Yao Oh, Xiaoying Koh, Joma Joy, May Ann Lee, Walter Stunkel, Vishal Pendharkar, Hannes Hentze, Siew Pheng Lim, Kantharaj Ethirajulu, C. S. Brian Chia, Joseph Cherian
16 Jul 2025 Entry Inhibitors of SARS-CoV-2 Targeting the Transmembrane Domain of the Spike Protein Kristin V. Lyles, Shannon Stone, Priti Singh, Lila D. Patterson, Janhavi Natekar, Heather Pathak, Rohit K. Varshnaya, Amany Elsharkawy, Dongning Liu, Shubham Bansal, Oluwafoyinsola O. Faniyi, Sijia Tang, Xiaoxiao Yang, Nagaraju Mulpuri, Donald Hamelberg, CongBao Kang, Binghe Wang, Mukesh Kumar, Ming Luo
15 May 2025 Towards global reaction feasibility and robustness prediction with high throughput data and bayesian deep learning Haowen Zhong, Yilan Liu, Haibin Sun, Yuru Liu, Rentao Zhang, Baochen Li, Yi Yang, Yuqing Huang, Fei Yang, Frankie S. Mak, Klement Foo, Sen Lin, Tianshu Yu, Peng Wang, Xiaoxue Wang
25 Apr 2025 Structure-based discovery of novel non-covalent small molecule inhibitors of USP30 Padmanabhan Anbazhagan, Jothi Anantharajan, Justina Fulwood, Choon Heng Low, Nithya Baburajendran, Klement Foo, Weijun Xu
10 Apr 2025 Therapeutic potential of targeting ubiquitin-specific proteases in colorectal cancer Chern Ein Oon, Padmanabhan Anbazhagan, Chong Teik Tan
24 Feb 2025 Fragment-Based Drug Design: From Then until Now, and Toward the Future Weijun Xu, CongBao Kang
24 Jan 2025 Leveraging Structural and Computational Biology for Molecular Glue Discovery CongBao Kang, Weijun Xu