Experimental Drug Development Centre

Date range:
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Publication date Article title Author(s)
14 May 2026 From Serendipity to Rationality: Expanding Druggability by Molecular Glue Discovery David E. Heppner, Congbao Kang, Weijun Xu
8 May 2026 Backbone resonance assignment of the Thalidomide Binding Domain (TBD) of cereblon Qiwei Huang, Hui Qi Ng, Congbao Kang
23 Apr 2026 Illuminating Clinical TEAD Inhibitors Through Structural Biology Congbao Kang, Weijun Xu, Haiwei Song, Wanjin Hong
3 Apr 2026 Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B Donghoon Chung, Yuka Otsuka, Eunjung Kim, Sultan Ullah, Nicole M. Kennedy, Khac Huy Ngo, Jinjoo Kang, Reece Tomlinson, Brian Alejandro, Koji Barnaby, Jeffrey Miller, Justin Shumate, Chwee Fang Teo, Yaw Bia Tan, Che Shin Chew, Congbao Kang, Dahai Luo, Louis Scampavia, Timothy P. Spicer, Thomas D. Bannister
26 Mar 2026 In Silico‐Enabled Discovery and Development of Potent and Selective CDK11 Inhibitors Frankie S. Mak, Fui Mee Ng, Padmanabhan Anbazhagan, Vikas Madan, Qian Wen Tan, Yiyang See, Diane Lim, Frances Karla Kusuma, Hannah Toh, Juliana Mohammad, Haiyan Yang, Sandra Sim, Li Hong Tan, Eileen Tay, Ronald Toh Kuan Hai, Perlyn Zekui Kwek, Mei Yee Wong, Deepika Raman, Qi An Ang, Vithya Manoharan, Susmitha Vuddagiri, Monique Danielle Dawson, Alison Tan, Joma Kanikadu Joy, Bong Hwa Gan, Choon Bing Low, Haoying Xu, Siew Pheng Lim, Hannes Hentze, Joseph Cherian, Chong Teik Tan, Jackie Ang, Kantharaj Ethirajulu, Klement Foo, Inderjeet Singh, Weijun Xu
14 Mar 2026 An inactive Zika NS2B-NS3pro protease construct for investigating allosteric inhibitors Khac Huy Ngo, Simon Lattmann, Paulina Duhita Anindita, Chong Wai Liew, Reuben S. Harris, Dahai Luo, Congbao Kang
26 Feb 2026 Discovery of Pan-TEAD Inhibitors That Disrupt YAP-TEAD Interaction as a Potential Therapy for Gastric Cancers and Mutant KRAS and EGFR Lung Cancers Ramesh Kumar, Joanne Thian, Joel D. W. Toh, Noorul Farzana, Jialin Sun, Congbao Kang, Suet Mei Crystal Low, Sheena Wee, Zijie Lim, Jayantha Gunaratne, Hui Mun Loh, Srinivasaraghavan Kannan, Chandra S. Verma, Sayan Chakraborty, Wanjin Hong
12 Feb 2026 Small-Molecule Drug Discovery Targeting RNAs: Hope or Hype? Congbao Kang, Hung T. Nguyen, David E. Heppner, Bin Yu, Weijun Xu
12 Feb 2026 Macrocycles: On the Rise for Bridging Small Molecules and Biologics Klement Foo, Kantharaj Ethirajulu, Weijun Xu
11 Dec 2025 Structural and Computational Biology: Compete or Complement? Congbao Kang, Haiwei Song, Weijun Xu