Experimental Drug Development Centre

Date range:
to
Publication date Article title Author(s)
15 Apr 2024 Cytotoxic activity and cell specificity of a novel LHRH peptide drug conjugate, D-Cys6-LHRH vedotin, against ovarian cancer cell lines Subramanyam Vankadara, Zhiyuan Ke, Sifang Wang, Sin Yun Foo, Jayantha Gunaratne, May Ann Lee, Xiaoying Koh, C. S. Brian Chia
15 Feb 2024 Identification of small‐molecule binding sites of a ubiquitin‐conjugating enzyme‐UBE2T through fragment‐based screening Yong Yao Loh, Jothi Anantharajan, Qiwei Huang, Weijun Xu, Justina Fulwood, Hui Qi Ng, Elizabeth Yihui Ng, Chong Yu Gea, Meng Ling Choong, Qian Wen Tan, Xiaoying Koh, Wan Hsin Lim, Kassoum Nacro, Joseph Cherian, Nithya Baburajendran, Zhiyuan Ke, CongBao Kang
11 Nov 2023 Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer Jothi Anantharajan, Qian Wen Tan, Justina Fulwood, Wang Sifang, Qiwei Huang, Hui Qi Ng, Xiaoying Koh, Weijun Xu, Joseph Cherian, Nithya Baburajendran, CongBao Kang, Zhiyuan Ke
24 Oct 2023 Targeted Degradation of XIAP is Sufficient and Specific to Induce Apoptosis in MYCN-overexpressing High-risk Neuroblastoma Zhang'E Choo, Xiaoying Koh, Megan Rui En Wong, Ruth Minothini Ashokan, Nurul Suhana Binte Ali Ahamed, CongBao Kang, Chik Hong Kuick, Kenneth Tou En Chang, Sarit Larisch, Amos Hong Pheng Loh, Zhi Xiong Chen
29 Sep 2023 Backbone 1H, 15N and 13C resonance assignments for an E2 ubiquitin conjugating enzyme-UBE2T Qiwei Huang, Hui Qi Ng, Yong Yao Loh, Zhiyuan Ke, Wan Hsin Lim, CongBao Kang
31 Jul 2023 Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules Qingxin Li, CongBao Kang
5 Jul 2023 Backbone 1H, 15N and 13C resonance assignments for dengue NS2B without the NS3 protease cofactor region in detergent micelles Qingxin Li, Hui Qi Ng, Ying Ru Loh, CongBao Kang
30 May 2023 A Patent Review on SARS Coronavirus Papain‐Like Protease (PL<sup>pro</sup>) Inhibitors C. S. Brian Chia, Siew Pheng Lim
26 Dec 2022 Targeting SARS-CoV-2 and host cell receptor interactions Siew Pheng Lim
23 Dec 2022 Novel PSMA-Targeting Radionuclide Peptidomimetics for Treating Prostate Cancer C. S. Brian Chia