Experimental Drug Development Centre

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Publication date Article title Author(s)
7 Jun 2019 Backbone resonance assignment for the full length tRNA-(N1G37) methyltransferase of Pseudomonas aeruginosa Yan Li, Wenhe Zhong, Ann Zhufang Koay, Hui Qi Ng, Qianhui Nah, Yee Hwa Wong, Jeffrey Hill, Julien Lescar, Peter C. Dedon, CongBao Kang
23 May 2019 Discovery of Irreversible Inhibitors Targeting Histone Methyltrans-ferase, SMYD3 Chuhui Huang, Si Si Liew, Grace R Lin, Anders Poulsen, Melgious J. Y. Ang, Brian C. S. Chia, Sin Yin Chew, Zekui Perlyn Kwek, John L. K. Wee, Esther H. Ong, Priya Retna, Nithya Baburajendran, Rong Li, Weixuan Yu, Xiaoying Koh-Stenta, Anna Ngo, Sravanthy Manesh, Justina Fulwood, Zhiyuan Ke, Hwa Hwa Chung, Sugunavathi Sepramaniam, Xin Hui Chew, Nurul Dinie, Yun Shan Chew, May Ann Lee, Choon Bing Low, Vishal Pendharkar, Vithya Manoharan, Susmitha Vuddagiri, Kanda Sangthongpitag, Joma Joy, Alex Matter, Jeffrey Hill, Thomas Keller, Klement Foo
8 Oct 2018 Backbone resonance assignment for the N-terminal region of bacterial tRNA-(N1G37) methyltransferase Yan Li, Wenhe Zhong, Ann Zhufang Koay, Hui Qi Ng, Xiaoying Koh-Stenta, Qianhui Nah, Siau Hoi Lim, Andreas Larsson, Julien Lescar, Jeffrey Hill, Peter C. Dedon, CongBao Kang
21 Sep 2018 Expression, purification of Zika virus membrane protein-NS2B in detergent micelles for NMR studies Elizabeth Yihui Ng, Ying Ru Loh, Yan Li, Qingxin Li, CongBao Kang
13 Aug 2018 Designing an ultra-short antibacterial peptide with potent activity against Mupirocin-resistant MRSA. Giovinna Arfan, Chu Yang Fann Ong, Siew Mei Samantha Ng, Qiu Ying Lau, Fui Mee Ng, Esther Hong Qian Ong, Jeffrey Hill, C. S. Brian Chia
11 Aug 2018 Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria Soo Yei Ho, Weiling Wang, Fui Mee Ng, Yun Xuan Wong, Zhi Ying Poh, Wai Sum Eldwin Tan, Shi Hua Ang, Si Si Liew, Yin Sze Joyner Wong, Yvonne Tan, Anders Poulsen, Vishal Pendharkar, Kanda Sangthongpitag, John Manchester, Gregory Basarab, Jeffrey Hill, Thomas H. Keller, Joseph Cherian
5 Jul 2018 Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide Bee Hui Liu, Chacko Jobichen, Cheng San Brian Chia, Tim Hon Man Chan, Jing Ping Tang, Theodora Chung, Jia Li, Anders Poulsen, Alvin W. Hung, Xiaoying Koh-Stenta, Yaw Sing Tan, Chandra S. Verma, Hong Kee Tan, Chan-shuo Wu, Feng Li, Jeffrey Hill, Joma Joy, Henry Yang, Li Chai, J. Sivaraman, Daniel G. Tenen
21 Jun 2018 Characterization of molecular interactions between Zika virus protease and peptides derived from the C-terminus of NS2B Yan Li, Ying Ru Loh, Alvin Wei Hung, CongBao Kang
23 May 2018 Structural and ligand binding analysis of the YAP-binding domain of transcription factor TEAD4 Yan Li, Shuang Liu, Elizabeth Yihui Ng, Rong Li, Anders Poulsen, Jeffrey Hill, CongBao Kang, Ajaybabu Pobbati, Alvin Wei Hung, Wanjin Hong, Thomas Keller
11 May 2018 Elucidating the bactericidal mechanism of action of the linear antimicrobial tetrapeptide BRBR-NH2. Qiu Ying Lau, Jianguo Li, Marc-Antoine Sani, Sheetal Sinha, Yan Li, Ng Fui Mee, Kang CongBao, Bhattacharjya Surajit, Separovic Frances, Verma Chandra, Chia Brian