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13 May 2023
BMRC
Bioinformatics Institute
A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays
Stephen H. Kasper,
Stephanie Otten,
Brian Squadroni,
Cionna Orr‐Terry,
Yi Kuang,
Lily Mussallem,
Lan Ge,
Lin Yan,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Christopher J. Brown,
Charles W. Johannes,
David P. Lane,
Arun Chandramohan,
Anthony W. Partridge,
Lee R. Roberts,
Hubert Josien,
Alex G. Therien,
Erik C. Hett,
Bonnie J. Howell,
Andrea Peier,
Xi Ai,
Jason Cassaday
Bioengineering & Translational Medicine
11 May 2020
BMRC
Bioinformatics Institute
Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability
Srinivasaraghavan Kannan,
Pietro G. A. Aronica,
Simon Ng,
Dawn Thean Gek Lian,
Yuri Frosi,
Sharon Chee,
Shimin Jiang,
Tsz Ying Yuen,
Ahmad Sadruddin,
Hung Yi Kristal Kaan,
Arun Chandramohan,
Yi Han,
Jin Huei Wong,
Yaw Sing Tan,
Zi Wei Chang,
Fernando Jose Ferrer-Gago,
Prakash Arumugam,
Shiying Chen,
Laurent Claude Stephane Renia,
Christopher J. Brown,
Charles W. Johannes,
Brian Henry,
David P. Lane,
Tomi K Sawyer,
Chandra S. Verma,
Anthony William Patridge
Chemical Science
2 Mar 2020
BMRC
p53 Laboratory
bioPROTACs as Versatile Modulators of Intracellular Therapeutic Targets Including Proliferating Cell Nuclear Antigen (PCNA)
Shuhui Lim,
Regina Khoo,
Khong Ming Peh,
Jinkai Teo,
Shih Chieh Chang,
Simon Ng,
Greg L. Beilhartz,
Roman A. Melnyk,
Charles W. Johannes,
Christopher J. Brown,
David P. Lane,
Brian Henry,
Anthony W. Patridge
Proceedings of the National Academy of Sciences of the United States of America
11 Dec 2019
SERC
Institute of Chemical and Engineering Sciences
Synthesis of chiral alkenyl cyclopropane amino acids for incorporation into stapled peptides
Tsz Ying Yuen,
Christopher J. Brown,
Yaw Sing Tan,
Charles W. Johannes
The Journal of Organic Chemistry
30 May 2019
BMRC
p53 Laboratory
Stereoisomerism of Stapled Peptide Inhibitors of the p53-Mdm2 Interaction: An Assessment of Synthetic Strategies and Activity Profiles
Tsz Ying Yuen,
Christopher J. Brown,
Yuezhen Xue,
Yaw Sing Tan,
Fernando J. Ferrer Gago,
Xue Er Lee,
Jin Yong Neo,
Dawn Thean,
Hung Yi Kristal Kaan,
Anthony W. Partridge,
Chandra S. Verma,
David P. Lane,
Charles W. Johannes
Chemical Science
30 May 2019
SERC
Institute of Chemical and Engineering Sciences
Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles
Tsz Ying Yuen,
Christopher J. Brown,
Yuezhen Xue,
Yaw Sing Tan,
Fernando J. Ferrer Gago,
Xue Er Lee,
Jin Yong Neo,
Dawn Thean,
Hung Yi Kristal Kaan,
Anthony W. Partridge,
Chandra S. Verma,
David P. Lane,
Charles W. Johannes
Chemical Science
8 Dec 2017
SERC
Institute of Chemical and Engineering Sciences
An intramolecular tryptophan-condensation approach for peptide stapling
Yaw Sing Tan,
Chandra S. Verma,
Kok-Ping Chan,
Charles W. Johannes,
Eunice Y.-L. Hui,
Bhimsen Rout
Organic & Biomolecular Chemistry
30 Aug 2017
SERC
Institute of Chemical and Engineering Sciences
One-pot Suzuki–Heck relay to prepare industrially valuable iniates using the Pd–Cy*Phine catalyst system
Uttam K. Das,
Roxanne Clément,
Charles W. Johannes,
Edward G. Robins,
Howard Jong,
R. Tom Baker
Catalysis Science & Technology
4 May 2017
SERC
Institute of Chemical and Engineering Sciences
Empirical and computational insights into N-arylation reactions catalyzed by palladium meta-terarylphosphine catalyst
Fui Fong Yong,
Adrian M. Mak,
Wenqin Wu,
Michael B. Sullivan,
Edward G. Robins,
Charles W. Johannes,
Howard Jong,
Yee Hwee Lim
ChemPlusChem
27 Jul 2016
BMRC
Singapore Bioimaging Consortium
Decarboxylative/Sonogashira-type cross-coupling using PdCl2(Cy*Phine)2
Yong Yang,
Yee Hwee Lim,
Edward G. Robins,
Charles W. Johannes
RSC Advances
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