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Publication date Communities Collections Article title Author(s) Journal/Conference
12 Jan 2024 BMRC Bioinformatics Institute Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G. Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra S. Verma, David P. Lane, Tomi K. Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J. Brown, Charles W. Johannes, Anthony W. Partridge Nature Communications
19 Sep 2023 BMRC Institute of Molecular and Cell Biology De Novo Sequencing of Synthetic Bis-cysteine Peptide Macrocycles Enabled by “Chemical Linearization” of Compound Mixtures Zhi’ang Chen, Yi Wee Lim, Jin Yong Neo, Rachel Shu Ting Chan, Li Quan Koh, Tsz Ying Yuen, Yee Hwee Lim, Charles W. Johannes, Zachary P. Gates Analytical Chemistry
13 May 2023 BMRC Bioinformatics Institute A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays Stephen H. Kasper, Stephanie Otten, Brian Squadroni, Cionna Orr‐Terry, Yi Kuang, Lily Mussallem, Lan Ge, Lin Yan, Srinivasaraghavan Kannan, Chandra S. Verma, Christopher J. Brown, Charles W. Johannes, David P. Lane, Arun Chandramohan, Anthony W. Partridge, Lee R. Roberts, Hubert Josien, Alex G. Therien, Erik C. Hett, Bonnie J. Howell, Andrea Peier, Xi Ai, Jason Cassaday Bioengineering & Translational Medicine
11 May 2020 BMRC Bioinformatics Institute Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability Srinivasaraghavan Kannan, Pietro G. A. Aronica, Simon Ng, Dawn Thean Gek Lian, Yuri Frosi, Sharon Chee, Shimin Jiang, Tsz Ying Yuen, Ahmad Sadruddin, Hung Yi Kristal Kaan, Arun Chandramohan, Yi Han, Jin Huei Wong, Yaw Sing Tan, Zi Wei Chang, Fernando Jose Ferrer-Gago, Prakash Arumugam, Shiying Chen, Laurent Claude Stephane Renia, Christopher J. Brown, Charles W. Johannes, Brian Henry, David P. Lane, Tomi K Sawyer, Chandra S. Verma, Anthony William Patridge Chemical Science
2 Mar 2020 BMRC p53 Laboratory bioPROTACs as Versatile Modulators of Intracellular Therapeutic Targets Including Proliferating Cell Nuclear Antigen (PCNA) Shuhui Lim, Regina Khoo, Khong Ming Peh, Jinkai Teo, Shih Chieh Chang, Simon Ng, Greg L. Beilhartz, Roman A. Melnyk, Charles W. Johannes, Christopher J. Brown, David P. Lane, Brian Henry, Anthony W. Patridge Proceedings of the National Academy of Sciences of the United States of America
11 Dec 2019 SERC Institute of Chemical and Engineering Sciences Synthesis of chiral alkenyl cyclopropane amino acids for incorporation into stapled peptides Tsz Ying Yuen, Christopher J. Brown, Yaw Sing Tan, Charles W. Johannes The Journal of Organic Chemistry
30 May 2019 BMRC p53 Laboratory Stereoisomerism of Stapled Peptide Inhibitors of the p53-Mdm2 Interaction: An Assessment of Synthetic Strategies and Activity Profiles Tsz Ying Yuen, Christopher J. Brown, Yuezhen Xue, Yaw Sing Tan, Fernando J. Ferrer Gago, Xue Er Lee, Jin Yong Neo, Dawn Thean, Hung Yi Kristal Kaan, Anthony W. Partridge, Chandra S. Verma, David P. Lane, Charles W. Johannes Chemical Science
30 May 2019 SERC Institute of Chemical and Engineering Sciences Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles Tsz Ying Yuen, Christopher J. Brown, Yuezhen Xue, Yaw Sing Tan, Fernando J. Ferrer Gago, Xue Er Lee, Jin Yong Neo, Dawn Thean, Hung Yi Kristal Kaan, Anthony W. Partridge, Chandra S. Verma, David P. Lane, Charles W. Johannes Chemical Science
8 Dec 2017 SERC Institute of Chemical and Engineering Sciences An intramolecular tryptophan-condensation approach for peptide stapling Yaw Sing Tan, Chandra S. Verma, Kok-Ping Chan, Charles W. Johannes, Eunice Y.-L. Hui, Bhimsen Rout Organic & Biomolecular Chemistry
30 Aug 2017 SERC Institute of Chemical and Engineering Sciences One-pot Suzuki–Heck relay to prepare industrially valuable iniates using the Pd–Cy*Phine catalyst system Uttam K. Das, Roxanne Clément, Charles W. Johannes, Edward G. Robins, Howard Jong, R. Tom Baker Catalysis Science & Technology