Search results

Publication date Communities Collections Article title Author(s)
1 Sep 2020 BMRC Bioinformatics Institute Critical role for cold shock protein YB-1 in cytokinesis Antony Braithwaite, Sunali Mehta, Michael Algie, Tariq Al-Jabry, Cushla McKinney, Srinivasaraghavan Kannan, Chandra S Verma, Weini Ma, Jessie Zhang, Tara K Bartolec, V. Pragathi Masamsetti, Kim Parker, Luke Henderson, Maree L Gould, Puja Bhatia, Rhodri Harfoot, Megan Chircop, Torsten Kleffmann, Scott B Cohen, Adele G Woolley, Anthony J Cesare
11 May 2020 BMRC Bioinformatics Institute Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability Srinivasaraghavan Kannan, Pietro G. A. Aronica, Simon Ng, Dawn Thean Gek Lian, Yuri Frosi, Sharon Chee, Shimin Jiang, Tsz Ying Yuen, Ahmad Sadruddin, Hung Yi Kristal Kaan, Arun Chandramohan, Yi Han, Jin Huei Wong, Yaw Sing Tan, Zi Wei Chang, Fernando Jose Ferrer-Gago, Prakash Arumugam, Shiying Chen, Laurent Claude Stephane Renia, Christopher J. Brown, Charles W. Johannes, Brian Henry, David P. Lane, Tomi K Sawyer, Chandra S. Verma, Anthony William Patridge
29 Apr 2020 BMRC Bioinformatics Institute Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation Li Ren Kong, Richard Weijie Ong, Tua Zea Tan, Nur Afiqah Binte Mohamed Salleh, Matan Thangavelu, Jane Vin Chan, Lie Yong Judice Koh, Giridharan Periyasamy, Jieying Amelia Lau, Thi Bich Uyen Le, Lingzhi Wang, Miyoung Lee, Srinivasaraghavan Kannan, Chandra S. Verma, Chwee Ming Lim, Wee Joo Chng, David P. Lane, Ashok Venkitaraman, Huynh The Hung, Chit Fang Cheok, Boon Cher Goh
25 Mar 2020 BMRC Bioinformatics Institute A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Li Ren Kong, Tuan Zea Tan, Nicholas L. Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel S W Tan, Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S. Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline S. J. Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H. Philip Koeffler, Soo Chin Lee, Dennis Kappei, Huyhn The Hung, Boon Cher Goh
28 Nov 2019 BMRC Bioinformatics Institute The Dual Interactions of p53 with MDM2 and p300: Implications for the Design of MDM2 Inhibitors Srinivasaraghavan Kannan, Anthony W. Partridge, David P. Lane, Chandra S. Verma
9 Jul 2019 BMRC Bioinformatics Institute A Novel Determinant of PSMD9 PDZ Binding Guides the Evolution of the First Generation of Super Binding Peptides Mohan R. Pradhan, Chandra S. Verma, Mahalakshmi Harish, Srinivasaraghavan Kannan, Srivalli Puttagunta, Prasanna Venkatraman
20 Jun 2019 BMRC Bioinformatics Institute Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties Anthony W. Patridge, Hung Yi Kristal Kaan, Yu-Chi Juang, Ahmad Sadruddin, Shuhui Lim, Christopher J. Brown, Simon Ng, Dawn Thean, Fernando Ferrer, Charles Johannes, Tsz Ying Yuen, Srinivasaraghavan Kannan, Pietro Aronica, Yaw Sing Tan, Mohan R. Praddhan, Chandra S. Verma, Jerome Hochman, Shiying Chen, Hui Wan, Sookhee Ha, Brad Sherbone, David P. Lane, Tomi K. Sawyer
29 May 2019 BMRC Bioinformatics Institute Characterization of Hydration Properties in Structural Ensembles of Biomolecules Mohan R. Pradhan, Minh N. Nguyen, Srinivasaraghavan Kannan, Stephen J. Fox, Chee Keong Kwoh, David P. Lane, Chandra S. Verma
28 May 2019 BMRC Bioinformatics Institute Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast Cancer Denis M. Collins, Neil T. Conlon, Srinivasaraghavan Kannan, Chandra S. Verma, Lisa D. Eli, Alshad S. Lalani, John Crown
17 May 2019 BMRC Bioinformatics Institute Exploring Gatekeeper Mutations in EGFR through Computer Simulations Srinivasaraghavan Kannan, Stephen J. Fox, Chandra S. Verma
9 Mar 2019 BMRC Bioinformatics Institute An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin Dominika Coufalova, Lucy Remnant, Lenka Hernychova, Petr Muller, Alan Healy, Srinivasaraghavan Kannan, Nicholas Westwood, Chandra S. Verma, Borek Vojtesek, Ted R. Hupp, Douglas R. Houston
15 Jan 2019 BMRC Bioinformatics Institute Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket Mohan R. Pradhan, Jia Wei Siau, Srinivasaraghavan Kannan, Minh N. Nguyen, Zohra Ouaray, Chee Keong Kwoh, David P. Lane, Farid Ghadessy, Chandra S. Verma
21 Jun 2018 BMRC Bioinformatics Institute Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket Srinivasaraghavan Kannan, Gireedhar Venkatachalam, Hong Hwa Lim, Uttam Surana, Chandra Verma
16 May 2018 BMRC Institute of Molecular and Cell Biology Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket Srinivasaraghavan Kannan, Gireedhar Venkatachalam, Hong Hwa Lim, Uttam Surana, Chandra Verma
16 May 2018 BMRC Bioinformatics Institute Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket Srinivasaraghavan Kannan, Gireedhar Venkatachalam, Hong Hwa Lim, Uttam Surana, Chandra Verma
23 Apr 2018 BMRC Bioinformatics Institute Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia Haiyan Yang, Lohitha Rao Chennamaneni, Melvyn Wai Tuck Ho, Shi Hua Ang, Eldwin Sum Wai Tan, Duraiswamy Athisayamani Jeyaraj, Yoon Sheng Yeap, Boping Liu, Esther Hq Ong, Joma Kanikadu Joy, John Liang Kuan Wee, Perlyn Kwek, Priya Retna, Nurul Dinie, Thuy Thi Hanh Nguyen, Shi Jing Tai, Vithya Manoharan, Vishal Pendharkar, Choon Bing Low, Yun Shan Chew, Susmitha Vuddagiri, Kanda Sangthongpitag, Meng Ling Choong, May Ann Lee, Srinivasaraghavan Kannan, Chandra S. Verma, Anders Poulsen, Sharon Lim, Charles Chuah, Tiong Sin Ong, Jeffrey Hill, Alex Matter, Kassoum Nacro
21 Jul 2016 BMRC Bioinformatics Institute PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition Pau Castel, Haley Ellis, Ruzica Bago, Eneda Toska, Pedram Razavi, F. Javier Carmona, Srinivasaraghavan Kannan, Chandra S. Verma, Maura Dickler, Sarat Chandarlapaty, Edi Brogi, Dario R. Alessi, Jose Baselga, Maurizio Scaltriti
31 Mar 2016 BMRC Bioinformatics Institute Long range recognition and selection in IDPs: the interactions of the C-terminus of p53 Srinivasaraghavan Kannan, David P. Lane, Chandra S. Verma
28 Oct 2015 BMRC Bioinformatics Institute Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteins Luigi Petrone, Akshita Kumar, Clarinda N. Sutanto, Navinkumar J. Patil, Srinivasaraghavan Kannan, Alagappan Palaniappan, Shahrouz Amini, Bruno Zappone, Chandra Verma, Ali Miserez