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1 Sep 2020
BMRC
Bioinformatics Institute
Critical role for cold shock protein YB-1 in cytokinesis
Antony Braithwaite,
Sunali Mehta,
Michael Algie,
Tariq Al-Jabry,
Cushla McKinney,
Srinivasaraghavan Kannan,
Chandra S Verma,
Weini Ma,
Jessie Zhang,
Tara K Bartolec,
V. Pragathi Masamsetti,
Kim Parker,
Luke Henderson,
Maree L Gould,
Puja Bhatia,
Rhodri Harfoot,
Megan Chircop,
Torsten Kleffmann,
Scott B Cohen,
Adele G Woolley,
Anthony J Cesare
Cancers
11 May 2020
BMRC
Bioinformatics Institute
Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability
Srinivasaraghavan Kannan,
Pietro G. A. Aronica,
Simon Ng,
Dawn Thean Gek Lian,
Yuri Frosi,
Sharon Chee,
Shimin Jiang,
Tsz Ying Yuen,
Ahmad Sadruddin,
Hung Yi Kristal Kaan,
Arun Chandramohan,
Yi Han,
Jin Huei Wong,
Yaw Sing Tan,
Zi Wei Chang,
Fernando Jose Ferrer-Gago,
Prakash Arumugam,
Shiying Chen,
Laurent Claude Stephane Renia,
Christopher J. Brown,
Charles W. Johannes,
Brian Henry,
David P. Lane,
Tomi K Sawyer,
Chandra S. Verma,
Anthony William Patridge
Chemical Science
29 Apr 2020
BMRC
Bioinformatics Institute
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation
Li Ren Kong,
Richard Weijie Ong,
Tua Zea Tan,
Nur Afiqah Binte Mohamed Salleh,
Matan Thangavelu,
Jane Vin Chan,
Lie Yong Judice Koh,
Giridharan Periyasamy,
Jieying Amelia Lau,
Thi Bich Uyen Le,
Lingzhi Wang,
Miyoung Lee,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Chwee Ming Lim,
Wee Joo Chng,
David P. Lane,
Ashok Venkitaraman,
Huynh The Hung,
Chit Fang Cheok,
Boon Cher Goh
Nature Communications
25 Mar 2020
BMRC
Bioinformatics Institute
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma
Nur Afiqah Binte Mohamed Salleh,
Richard Weijie Ong,
Li Ren Kong,
Tuan Zea Tan,
Nicholas L. Syn,
Robby Miguel Goh,
Chee Wai Fhu,
Daniel S W Tan,
Gopalakrishna Iyer,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Yaw Chyn Lim,
Ross Soo,
Jingshan Ho,
Yiqing Huang,
Joline S. J. Lim,
Benedict Junrong Yan,
Min En Nga,
Seng Gee Lim,
H. Philip Koeffler,
Soo Chin Lee,
Dennis Kappei,
Huyhn The Hung,
Boon Cher Goh
Nature Communications
28 Nov 2019
BMRC
Bioinformatics Institute
The Dual Interactions of p53 with MDM2 and p300: Implications for the Design of MDM2 Inhibitors
Srinivasaraghavan Kannan,
Anthony W. Partridge,
David P. Lane,
Chandra S. Verma
International Journal of Molecular Sciences
9 Jul 2019
BMRC
Bioinformatics Institute
A Novel Determinant of PSMD9 PDZ Binding Guides the Evolution of the First Generation of Super Binding Peptides
Mohan R. Pradhan,
Chandra S. Verma,
Mahalakshmi Harish,
Srinivasaraghavan Kannan,
Srivalli Puttagunta,
Prasanna Venkatraman
Biochemistry
20 Jun 2019
BMRC
Bioinformatics Institute
Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties
Anthony W. Patridge,
Hung Yi Kristal Kaan,
Yu-Chi Juang,
Ahmad Sadruddin,
Shuhui Lim,
Christopher J. Brown,
Simon Ng,
Dawn Thean,
Fernando Ferrer,
Charles Johannes,
Tsz Ying Yuen,
Srinivasaraghavan Kannan,
Pietro Aronica,
Yaw Sing Tan,
Mohan R. Praddhan,
Chandra S. Verma,
Jerome Hochman,
Shiying Chen,
Hui Wan,
Sookhee Ha,
Brad Sherbone,
David P. Lane,
Tomi K. Sawyer
Molecules
29 May 2019
BMRC
Bioinformatics Institute
Characterization of Hydration Properties in Structural Ensembles of Biomolecules
Mohan R. Pradhan,
Minh N. Nguyen,
Srinivasaraghavan Kannan,
Stephen J. Fox,
Chee Keong Kwoh,
David P. Lane,
Chandra S. Verma
Journal of Chemical Information and Modeling
28 May 2019
BMRC
Bioinformatics Institute
Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast Cancer
Denis M. Collins,
Neil T. Conlon,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Lisa D. Eli,
Alshad S. Lalani,
John Crown
Cancers
17 May 2019
BMRC
Bioinformatics Institute
Exploring Gatekeeper Mutations in EGFR through Computer Simulations
Srinivasaraghavan Kannan,
Stephen J. Fox,
Chandra S. Verma
Journal of Chemical Information and Modeling
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