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22 Mar 2022
BMRC
Institute of Bioengineering and Bioimaging
Drug-free neutrally charged polypeptide nanoparticles as anticancer agents
Shengcai Yang,
Jiayu Leong,
Yanming Wang,
Rachel Sim,
Ko Hui Tan,
Yau Hong Chua,
Nathanael Tan,
Ashlynn L.Z. Lee,
Joyce Tay,
Yi Yan Yang
Journal of Controlled Release
30 Nov 2021
BMRC
Institute of Bioengineering and Bioimaging
Antimicrobial Polypeptides Capable of Membrane Translocation for Treatment of MRSA Wound Infection In Vivo
Shengcai Yang,
Yanming Wang,
Jason Tan,
Jye Yng Teo,
Ko Hui Tan,
Yi Yan Yang
Advanced Healthcare Materials
5 May 2020
BMRC
Bioinformatics Institute
De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits
Simon Ng,
Yu-Chi Juang,
Arun Chandramohan,
Hung Yi Kristal Kaan,
Ahmad Sadruddin,
Tsz Ying Yuen,
Fernando J. Ferrer-Gago,
Xue'Er Cheryl Lee,
Liew Xi,
Charles W. Johanes,
Christopher J. Brown,
Srinivasaraghavan Kanan,
Pietro G. Aronica,
Nils A. Berglund,
Chandra S. Verma,
Lijuan Liu,
Alexander Stoeck,
Tomi K. Sawyer,
Anthony W. Partridge,
David P. Lane
ACS Medicinal Chemistry Letters
19 Apr 2020
BMRC
p53 Laboratory
Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks
Sara Lundsten,
Víctor Agmo Hernández,
Lars Gedda,
Tina Sarén,
Christopher J. Brown,
David P. Lane,
Katarina Edwards,
Marika Nestor
Nanomaterials
7 Feb 2020
BMRC
Bioinformatics Institute
Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products
Jitka Petrolova,
Ganna Petruk,
Roland G. Huber,
Eilish W. McBurnie,
Mariena J. A. van der Plas,
Peter J. Bond,
Manoj Puthia,
Artur Schmidtchen
Journal of Biological Chemistry
28 Nov 2019
BMRC
Bioinformatics Institute
The Dual Interactions of p53 with MDM2 and p300: Implications for the Design of MDM2 Inhibitors
Srinivasaraghavan Kannan,
Anthony W. Partridge,
David P. Lane,
Chandra S. Verma
International Journal of Molecular Sciences
9 Jul 2019
BMRC
Bioinformatics Institute
A Novel Determinant of PSMD9 PDZ Binding Guides the Evolution of the First Generation of Super Binding Peptides
Mohan R. Pradhan,
Chandra S. Verma,
Mahalakshmi Harish,
Srinivasaraghavan Kannan,
Srivalli Puttagunta,
Prasanna Venkatraman
Biochemistry
29 May 2019
BMRC
Bioinformatics Institute
Characterization of Hydration Properties in Structural Ensembles of Biomolecules
Mohan R. Pradhan,
Minh N. Nguyen,
Srinivasaraghavan Kannan,
Stephen J. Fox,
Chee Keong Kwoh,
David P. Lane,
Chandra S. Verma
Journal of Chemical Information and Modeling
6 Jun 2018
BMRC
Bioinformatics Institute
Influence of pH on the activity of thrombin-derived antimicrobial peptides
Daniel A. Holdbrook,
Shalini Singh,
Yeu Khai Choong,
Jitka Petrlova,
Martin Malmsten,
Peter J. Bond,
Navin Kumar Verma,
Artur Schmidtchen,
Rathi Saravanan
Biochimica et Biophysica Acta (BBA) - Biomembranes
15 Nov 2017
BMRC
p53 Laboratory
Characterizing the conformational landscape of MDM2-binding p53 peptides using Molecular Dynamics simulations
Shilpa Yadahalli,
Jianguo Li,
David P. Lane,
Shachi Gosavi,
Chandra S. Verma
Scientific Reports
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