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8 Dec 2023
BMRC
Skin Research Institute of Singapore
Automated Electrical Stimulation Therapy Accelerates Re-Epithelialization in a Three-Dimensional In Vitro Human Skin Wound Model
Priscilla L.K. Lim,
Yamini Balakrishnan,
Gracia Goh,
Khek-Chian Tham,
Yi Zhen Ng,
Declan P. Lunny,
David I. Leavesley,
Carine Bonnard
Advances in Wound Care
29 Aug 2023
BMRC
Skin Research Lab
Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis
Kim Samirah Robinson,
Gee Ann Toh,
Muhammad Jasrie Firdaus,
Khek Chian Tham,
Pritisha Rozario,
Chrissie K. Lim,
Ying Xiu Toh,
Zhi Heng Lau,
Sophie Charlotte Binder,
Jacob Mayer,
Carine Bonnard,
Florian I. Schmidt,
John E.A. Common,
Franklin L. Zhong
Journal of Experimental Medicine
15 Jul 2022
BMRC
Skin Research Lab
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome
(Pending publish)
Kim S. Robinson,
Gee Ann Toh,
Pritisha Rozario,
Rae Chua,
Stefan Bauernfried,
Zijin Sun,
Muhammad Jasrie Firdaus,
Shima Bayat,
Rhea Nadkarni,
Zhi Sheng Poh,
Khek Chian Tham,
Cassandra R. Harapas,
Chrissie K. Lim,
Werncui Chu,
Celest W. S. Tay,
Kiat Yi Tan,
Tianyun Zhao,
Carine Bonnard,
Radoslaw Sobota,
John E. Connolly,
John Common,
Seth L. Masters,
Kaiwen W. Chen,
Lena Ho,
Bin Wu,
Veit Hornung,
Franklin L. Zhong
Science
30 Jan 2020
BMRC
Institute of Molecular and Cell Biology
Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy
Monica Yau,
Nader Handal,
Werner Deigendesch,
Reinhard Keimer,
Hiyam M. Marzouqa,
Holger Hengel,
Célia Bosso-Lefèvre,
George Grady,
Emmanuelle Szenker-Ravi,
Hankun Li,
Sarah Pierce,
Élise Lebigot,
Thong-Teck Tan,
Michelle Y. Eio,
Gunaseelan Narayanan,
Kagistia Hana Utami,
Meral Gunay-Aygun,
Michael J. Muriello,
Helene Verhelst,
Sarah Weckhuysen,
Sonal Mahida,
Sakkubai Naidu,
Terrence G. Thomas,
Jiin Ying Lim,
Ee Shien Tan,
Damien Haye,
Michèl A. A. P. Willemsen,
Renske Oegema,
Wendy G. Mitchell,
Tyler Mark Pierson,
Marisa V. Andrews,
Marcia C. Willing,
Lance H. Rodan,
Tahsin Stefan Barakat,
Marjon van Slegtenhorst,
Ralitza H. Gavrilova,
Diego Martinelli,
Tal Gilboa,
Abdullah M. Tamim,
Mais O. Hashem,
Moeenaldeen D. AlSayed,
Maha M. Abdulrahim,
Mohammed Al-Owain,
Ali Awaji,
Adel A. H. Mahmoud,
Eissa A. Faqeih,
Ali Al Asmari,
Sulwan M. Algain,
Lamyaa A. Jad,
Hesham M. Aldhalaan,
Ingo Helbig,
David A. Koolen,
Angelika Riess,
Ingeborg Kraegeloh-Mann,
Peter Bauer,
Suleyman Gulsuner,
Hannah Stamberger,
Alvin Yu Jin Ng,
Sha Tang,
Sumanty Tohari,
Boris Keren,
Laura E. Schultz-Rogers,
Eric W. Klee,
Sabina Barresi,
Marco Tartaglia,
Hagar Mor-Shaked,
Sateesh Maddirevula,
Amber Begtrup,
Aida Telegrafi,
Rolph Pfundt,
Rebecca Schüle,
Brian Ciruna,
Carine Bonnard,
Mahmoud A. Pouladi,
James C. Stewart,
Adam Claridge-Chang,
Dirk J. Lefeber,
Fowzan S. Alkuraya,
Bruno Reversade,
Ajay S. Mathuru,
Byrappa Venkatesh,
Joseph J. Barycki,
Melanie A. Simpson,
Saumya S. Jamuar,
Ludger Schöls
Nature Communications
8 Jul 2019
BMRC
Institute of Molecular and Cell Biology
Novel mutation in HTRA1 in a family with diffuse white matter lesions and inflammatory features
Amin Ziaei,
Xiaohong Xu,
Leila Dehghani,
Carine Bonnard,
Andreas Zellner,
Alvin Yu Jin Ng,
Sumanty Tohari,
Byrappa Venkatesh,
Christof Haffner,
Bruno Reversade,
Vahid Shaygannejad,
Mahmoud A. Pouladi
Neurology Genetics
24 Jul 2018
BMRC
Institute of Molecular and Cell Biology
Cenani-Lenz syndactyly syndrome - a case report of a family with isolated syndactyly
Dineshani Hettiaracchchi,
Carine Bonnard,
S. M. A. Jayawardana,
Alvin Yu Jin Ng,
Sumanty Tohari,
Byrappa Venkatesh,
Bruno Reversade,
Roshni Singaraja,
V. H. W. Dissanayake
BMC Medical Genetics
28 Dec 2017
BMRC
Institute of Molecular and Cell Biology
KIAA1109 Variants Are Associated with a Severe Disorder of Brain Development and Arthrogryposis
Lucie Gueneau,
Richard J. Fish,
Hanan E. Shamseldin,
Norine Voisin,
Frédéric Tran Mau-Them,
Egle Preiksaitiene,
Glen R. Monroe,
Angeline Lai,
Audrey Putoux,
Fabienne Allias,
Qamariya Ambusaidi,
Laima Ambrozaityte,
Loreta Cimbalistienė,
Julien Delafontaine,
Nicolas Guex,
Mais Hashem,
Wesam Kurdi,
Saumya Shekhar Jamuar,
Lim J. Ying,
Carine Bonnard,
Tommaso Pippucci,
Sylvain Pradervand,
Bernd Roechert,
Peter M. van Hasselt,
Michaël Wiederkehr,
Caroline F. Wright,
Ioannis Xenarios,
Gijs van Haaften,
Charles Shaw-Smith,
Erica M. Schindewolf,
Marguerite Neerman-Arbez,
Damien Sanlaville,
Gaëtan Lesca,
Laurent Guibaud,
Bruno Reversade,
Jamel Chelly,
Vaidutis Kučinskas,
Fowzan S. Alkuraya,
Alexandre Reymond,
Alexandre Reymond
The American Journal of Human Genetics
28 Sep 2017
BMRC
Skin Research Lab
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis
(Pending publish)
Marwa Chourabi,
Mei Shan Liew,
Shawn Lim,
Dorra H’mida-Ben Brahim,
Lobna Boussofara,
Liang Dai,
Pui Mun Wong,
Jia Nee Foo,
Badreddine Sriha,
Kim Samirah Robinson,
Simon Denil,
John EA Common,
Ons Mamai,
Youcef Ben Khalifa,
Mathieu Bollen,
Jianjun Liu,
Mohamed Denguezli,
Carine Bonnard,
Ali Saad,
Bruno Reversade
Journal of Investigative Dermatology
7 Sep 2017
BMRC
Institute of Molecular and Cell Biology
CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays
Katharina Roetzer,
Paul Roschger,
Klaus Klaushofer,
Janine Altmüller,
Sudipto Roy,
Byrappa Venkatesh,
Rudolf Ganger,
Franz Grill,
Christian Windpassinger,
Juliette Piard,
Carine Bonnard,
Majid Alfadhel,
Shuhui Lim,
Xavier Bisteau,
Verena Rupp,
Stéphane Blouin,
Nur’Ain B. Ali,
Alvin Yu Jin Ng,
Hao Lu,
Sumanty Tohari,
S. Zakiah A. Talib,
Noémi van Hul,
Matias J. Caldez,
Lionel Van Maldergem,
Gökhan Yigit,
Hulya Kayserili,
Sameh A. Youssef,
Vincenzo Coppola,
Alain de Bruin,
Lino Tessarollo,
Hyungwon Choi,
Farid Ben Chehida,
Bernd Wollnik,
Umut Altunoglu,
Ali Al Kaissi,
Bruno Reversade,
Philipp Kaldis
American Journal of Human Genetics (AJHG)
17 Dec 2014
BMRC
Institute of Medical Biology
Katanin p80 regulates human cortical development by limiting centriole and cilia number
Mohammed Al-Dosari,
Anas Alazami,
Mohammed Alowain,
Fowzan S. Alkuraya,
Jeremy F. Reiter,
Matthew P. Harris,
Bruno Reversade,
Christopher A. Walsh,
Wen F. Hu,
Oz Pomp,
Tawfeg Ben-Omran,
Andrew Kodani,
Katrin Henke,
Ganeshwaran H. Mochida,
Timothy W. Yu,
Mollie B. Woodworth,
Carine Bonnard,
Grace Selva Raj,
Thong Teck Tan,
Hanan Hamamy,
Amira Masri,
Mohammad Shboul,
Muna Al Saffar,
Jennifer N. Partlow
Neuron
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