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18 May 2022
|
BMRC
|
Institute of Molecular and Cell Biology
|
Targeted ablation of Lgr5-expressing intestinal stem cells in diphtheria toxin receptor-based mouse and organoid models
|
Hui Yi Grace Lim,
Swathi Yada,
Nick Barker
|
STAR Protocols
|
|
10 Mar 2022
|
BMRC
|
Institute of Molecular and Cell Biology
|
Editorial: Humanized Mouse Models to Study Immune Responses to Human Infectious Organisms
|
Melissa Xin Yu Wong,
Qingfeng Chen
|
Frontiers in Immunology
|
|
15 Feb 2022
|
BMRC
|
Institute of Molecular and Cell Biology
|
Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
|
Jia Tong Loh,
Bin Zhang,
Joey Kay Hui Teo,
Ruenn Chai Lai,
Andre Boon Hwa Choo,
Kong-Peng Lam,
Sai Kiang Lim
|
Cytotherapy
|
|
31 Jan 2022
|
BMRC
|
Singapore Immunology Network
|
Human Milk Antibodies after BNT162b2 Vaccination Exhibit Reduced Binding against SARS-CoV-2 Variants of Concern
|
Jia Ming Low,
Yue Gu,
Melissa Shu Feng Ng,
Liang Wei Wang,
Zubair Amin,
Youjia Zhong,
Paul A. MacAry
|
Vaccines
|
|
25 Jan 2022
|
BMRC
|
Institute of Molecular and Cell Biology
|
Unraveling B cell trajectories at single cell resolution
|
Dhakshayini Morgan,
Vinay Tergaonkar
|
Trends in Immunology
|
|
24 Nov 2021
|
BMRC
|
Skin Research Institute of Singapore
|
Skin microbiome of atopic dermatitis
|
Li Fang Koh,
Ruo Yan Ong,
John E. Common
|
Allergology International
|
|
26 Jul 2021
|
BMRC
|
Singapore Institute for Clinical Sciences
|
Atopic dermatitis trajectories to age 8 years in the GUSTO cohort
|
Noor H. A. Suaini,
Gaik Chin Yap,
Do Phuong Tung Bui,
Evelyn Xiu Ling Loo,
Anne Eng Neo Goh,
Oon Hoe Teoh,
Kok Hian Tan,
Keith M. Godfrey,
Bee Wah Lee,
Lynette Pei‐chi Shek,
Hugo Van Bever,
Yap Seng Chong,
Elizabeth Huiwen Tham
|
Clinical and Experimental Allergy
|
|
22 Mar 2021
|
BMRC
|
Singapore Institute for Clinical Sciences
|
Children of Asian ethnicity in Australia have higher risk of food allergy and early‐onset eczema than those in Singapore
|
Noor H. A. Suaini,
Evelyn Xiu‐Ling Loo,
Rachel L. Peters,
Gaik Chin Yap,
Katrina J. Allen,
Hugo Van Bever,
David J. Martino,
Anne Eng Neo Goh,
Shyamali C. Dharmage,
Marjorelee T. Colega,
Mary Foong Fong Chong,
Anne‐Louise Ponsonby,
Kok Hian Tan,
Mimi L. K. Tang,
Keith M. Godfrey,
Bee Wah Lee,
Lynette Pei‐chi Shek,
Jennifer J. Koplin,
Elizabeth Huiwen Tham
|
Allergy
|
|
26 Aug 2020
|
BMRC
|
Singapore Institute for Clinical Sciences
|
Global differences in atopic dermatitis
|
Noor H. A. Suaini,
Cheryl P. T. Tan,
Evelyn X. L. Loo,
Elizabeth Huiwen Tham
|
Pediatric Allergy and Immunology
|
|
16 Apr 2020
|
BMRC
|
Institute of Molecular and Cell Biology
|
IRF-7 Mediates Type I IFN Responses in Endotoxin-Challenged Mice
|
Wei-Xiang Sin,
Joe Poh-Sheng Yeong,
Thomas Jun Feng Lim,
I-Hsin Su,
John Edward Connolly,
Keh-Chuang Chin
|
Frontiers in Immunology
|
|
18 Feb 2020
|
BMRC
|
Singapore Immunology Network
|
Plasmodium-infected erythrocytes induce secretion of IGFBP7 to form type II rosettes and escape phagocytosis
|
Wenn-Chyau Lee,
Bruce Russell,
Radoslaw Mikolaj Sobota,
Khairunnisa Ghaffar,
Shanshan W Howland,
Zi Xin Wong,
Alexander G. Maier,
Dominique Dorin-Semblat,
Subhra Biswas,
Benoit Gamain,
Yee-Ling Lau,
Benoit Malleret,
Cindy Chu,
François Nosten,
Laurent Renia
|
eLife
|
|
22 Oct 2019
|
BMRC
|
Institute of Molecular and Cell Biology
|
Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases
|
Gökhan Cildir,
John Toubia,
Kwok Ho Yip,
Mingyan Zhou,
Harshita Pant,
Pravin Hissaria,
Jingxian Zhang,
Wanjin Hong,
Nirmal Robinson,
Michele A. Grimbaldeston,
Angel F. Lopez,
Vinay Tergaonkar
|
Immunity
|
|
4 Jul 2019
|
BMRC
|
Bioprocessing Technology Institute
|
von Hippel-Lindau Protein Maintains Metabolic Balance to Regulate the Survival of Naive B Lymphocytes
|
Shengli Xu,
Jianxin Huo,
Yuhan Huang,
Melissa Aw,
Shuwen Chen,
Shiya Mak,
Lian Yee Yip,
Ying Swan Ho,
Sze Wai Ng,
Andy Hee-Meng Tan,
Alison Lee,
Xijun Ou,
Kong-Peng Lam
|
iSCIENCE
|
|
10 Jun 2019
|
BMRC
|
Bioprocessing Technology Institute
|
Dok3–protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity
|
Jia Tong Loh,
Shengli Xu,
Jian Xin Huo,
Susana Soo-Yeon Kim,
Yue Wang,
Kong-Peng Lam
|
Journal of Clinical Investigation
|
|
25 Feb 2019
|
BMRC
|
Bioprocessing Technology Institute
|
The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance IFN-β response
|
Susana Soo-Yeon Kim,
Lynette Sze,
Kong-Peng Lam
|
Journal of Biological Chemistry
|
|
13 Nov 2018
|
BMRC
|
Bioprocessing Technology Institute
|
Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells
|
Jia Tong Loh,
Thomas Jun Feng Lim,
Kyoko Ikumi,
Takuma Matoba,
Baptiste Janela,
Merry Gunawan,
Tatsuya Toyama,
Maegan Bunjamin,
Lai Guan Ng,
Michael Poidinger,
Akimichi Morita,
Florent Ginhoux,
Sayuri Yamazaki,
Kong-Peng Lam,
I-Hsin Su
|
iScience
|
|
12 Mar 2018
|
BMRC
|
Bioinformatics Institute
|
Effect of VH–VL Families in Pertuzumab and Trastuzumab Recombinant Production, Her2 and FcγIIA Binding
|
Wei-Li Ling,
Wai-Heng Lua,
Jun-Jie Poh,
Joshua Yi Yeo,
David Philip Lane,
Samuel Ken-En Gan
|
Frontiers in Immunology
|
|
7 Feb 2018
|
BMRC
|
Institute of Molecular and Cell Biology
|
Humanized Mice as Unique Tools for Human-Specific Studies
|
Kylie Su Mei Yong,
Zhisheng Her,
Qingfeng Chen
|
Archivum Immunologiae et Therapiae Experimentalis
|
|
28 Nov 2017
|
BMRC
|
Institute of Molecular and Cell Biology
|
Elimination of tumor by CD47/PD-L1 dual-targeting fusion protein that engages innate and adaptive immune responses
|
Boning Liu,
Huaizu Guo,
Jin Xu,
Ting Qin,
Qingcheng Guo,
Nana Gu,
Dapeng Zhang,
Weizhu Qian,
Jianxin Dai,
Sheng Hou,
Hao Wang,
Yajun Guo
|
mAbs
|
|
23 Oct 2017
|
BMRC
|
Institute of Molecular and Cell Biology
|
A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans
|
Rebecca S. Shapiro,
Alejandro Chavez,
Caroline B. M. Porter,
Meagan Hamblin,
Christian S. Kaas,
James E. DiCarlo,
Guisheng Zeng,
Xiaoli Xu,
Alexey V. Revtovich,
Natalia V. Kirienko,
Yue Wang,
George M. Church,
James J. Collins
|
Nature Microbiology
|
|
28 Apr 2017
|
BMRC
|
Singapore Institute for Clinical Sciences
|
Relation of infant dietary patterns to allergic outcomes in early childhood
|
Evelyn Xiu Ling Loo,
Jordan Zheng Ting Sim,
Jia Ying Toh,
Anne Goh,
Oon Hoe Teoh,
Yiong Huak Chan,
Seang Mei Saw,
Kenneth Kwek,
Kok Hian Tan,
Peter D. Gluckman,
Keith M. Godfrey,
Hugo Van Bever,
Bee Wah Lee,
Yap Seng Chong,
Mary Foong-Fong Chong,
Lynette Pei-chi Shek
|
Pediatric Allergy and Immunology
|
|
7 Jun 2016
|
BMRC
|
Bioprocessing Technology Institute
|
T Lymphocyte Activation Markers as Predictors of Responsiveness to Rituximab among Patients with FSGS
|
L. P. Resontoc,
K.-H. Ng,
Y.-H. Chan,
P. Y.-W. Lau,
C.-Y. Chan,
I. D. Liu,
M. Than,
S. C. Jordan,
K.-P. Lam,
W.-S. Yeo,
H.-K. Yap
|
Clinical Journal of the American Society of Nephrology
|
|
31 Dec 2015
|
BMRC
|
Institute of Medical Biology
|
Applying extracellular vesicles based therapeutics in clinical trials
|
Thomas Lener,
Mario Gimona,
Ludwig Aigner,
Verena Börger,
Edit Buzas,
Giovanni Camussi,
Nathalie Chaput,
Devasis Chatterjee,
Felipe A. Court,
Hernando A. del Portillo,
Lorraine O’Driscoll,
Stefano Fais,
Juan M. Falcón-Pérez,
Ursula Felderhoff-Mueser,
Lorenzo Fraile,
Yong Song Gho,
André Görgens,
Ramesh C. Gupta,
An Hendrix,
Dirk M. Hermann,
Andrew F. Hill,
Fred Hochberg,
Peter A. Horn,
Dominique De Kleijn,
Lambros Kordelas,
Boris W. Kramer,
Eva-Maria Krämer-Albers,
Sandra Laner-Plamberger,
Saara Laitinen,
Tommaso Leonardi,
Magdalena J. Lorenowicz,
Sai Kiang Lim,
Jan Lötvall,
Casey A. Maguire,
Antonio Marcilla,
Irina Nazarenko,
Takahiro Ochiya,
Tushar Patel,
Shona Pedersen,
Gabriella Pocsfalvi,
Stefano Pluchino,
Peter Quesenberry,
Ilona G. Reischl,
Francisco J. Rivera,
Ralf Sanzenbacher,
Katharina Schallmoser,
Ineke Slaper-Cortenbach,
Dirk Strunk,
Torsten Tonn,
Pieter Vader,
Bas W. M. van Balkom,
Marca Wauben,
Samir El Andaloussi,
Coltilde Thery,
Eva Rohde,
Bernd Giebel
|
Journal of Extracellular Vesicles
|
|
21 Aug 2015
|
BMRC
|
Bioprocessing Technology Institute
|
BTK: sensing pathogenic nucleic acids
|
Koon-Guan Lee,
Kong Peng Lam
|
Oncotarget
|
|
22 Jul 2014
|
BMRC
|
Bioprocessing Technology Institute
|
Adaptor protein DOK3 promotes plasma cell differentiation by regulating the expression of programmed cell death 1 ligands
|
X. Ou,
S. Xu,
Y.-F. Li,
K.-P. Lam
|
Proceedings of the National Academy of Sciences
|
|
30 Jun 2014
|
BMRC
|
Bioprocessing Technology Institute
|
Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool
|
Yan-Feng Li,
Shengli Xu,
Xijun Ou,
Kong-Peng Lam
|
Nature Communications
|
|
26 Jun 2014
|
BMRC
|
Singapore Institute for Clinical Sciences
|
Toll-Like Receptor 8 Agonist and Bacteria Trigger Potent Activation of Innate Immune Cells in Human Liver
|
Juandy Jo,
Anthony T. Tan,
James E. Ussher,
Elena Sandalova,
Xin-Zi Tang,
Alfonso Tan-Garcia,
Natalie To,
Michelle Hong,
Adeline Chia,
Upkar S. Gill,
Patrick T. Kennedy,
Kai Chah Tan,
Kang Hoe Lee,
Gennaro De Libero,
Adam J. Gehring,
Christian B. Willberg,
Paul Klenerman,
Antonio Bertoletti,
Christopher M. Walker
|
PLoS Pathogens
|
|
13 Jun 2014
|
BMRC
|
Bioprocessing Technology Institute
|
DOK3 Is Required for IFN- Production by Enabling TRAF3/TBK1 Complex Formation and IRF3 Activation
|
C.-S. Chin,
S.-K. Ng,
N. A. Pereira,
S. S.-Y. Kim,
K.-G. Lee,
S. Xu,
K.-P. Lam
|
The Journal of Immunology
|
|
13 Nov 2013
|
BMRC
|
Singapore Institute for Clinical Sciences
|
Immunoprevalence and Immunodominance of HLA-Cw*0801-Restricted T Cell Response Targeting the Hepatitis B Virus Envelope Transmembrane Region
|
A. T. Tan,
P. Sodsai,
A. Chia,
E. Moreau,
M. H. Y. Chng,
C. Y. L. Tham,
Z. Z. Ho,
N. Banu,
N. Hirankarn,
A. Bertoletti
|
Journal of Virology
|
|
11 Sep 2013
|
SERC
|
Institute of Materials Research and Engineering
|
Hybrid polymersomes: facile manipulation of vesicular surfaces for enhancing cellular interaction (Pending publish)
|
Xingfang Su,
Shaqireen Kwajah Mohamed Moinuddeen,
Lucia Mori,
Madhavan Nallani
|
Journal of Materials Chemistry B
|
|
27 Sep 2011
|
BMRC
|
Singapore Immunology Network
|
Mesenchymal Transition and Dissemination of Cancer Cells Is Driven by Myeloid-Derived Suppressor Cells Infiltrating the Primary Tumor (Pending publish)
|
Benjamin Toh,
Xiaojie Wang,
Jo Keeble,
Wen Jing Sim,
Karen Khoo,
Wing-Cheong Wong,
Masashi Kato,
Armelle Prévost-Blondel,
Jean-Paul Thiery,
Jean-Pierre Abastado
|
PLoS Biology
|