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7 May 2021
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BMRC
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Bioprocessing Technology Institute
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Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response
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Koon-Guan Lee,
Susana Soo-Yeon Kim,
Lin Kui,
Dominic Chih-Cheng Voon,
Marjorie Mauduit,
Pradeep Bist,
Xuezhi Bi,
Natasha Ann Pereira,
Chengcheng Liu,
Bindu Sukumaran,
Laurent Renia,
Yoshiaki Ito,
Kong-Peng Lam
|
Cell Reports
|
|
20 Nov 2020
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BMRC
|
Bioprocessing Technology Institute
|
TACI constrains TH17 pathogenicity and protects against gut inflammation
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Sean Jing Xiang Tan,
Arleen Sanny,
Xijun Ou,
Sze-Wai Ng,
Alex Xing Fah Wong,
Gloria Hoi Wan Tso,
Biyan Zhang,
Pei-Yun Teo,
Susana Soo-Yeon Kim,
Alison P. Lee,
Shengli Xu,
Kong-Peng Lam,
Andy Hee-Meng Tan
|
iSCIENCE
|
|
29 Sep 2020
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BMRC
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Bioprocessing Technology Institute
|
Emerging Roles of Downstream of Kinase 3 in Cell Signaling
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Jia Tong Loh,
Kay Hui Teo Joey,
Hong-Hwa Lim,
Kong-Peng Lam
|
Frontiers in Immunology
|
|
1 Mar 2020
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BMRC
|
Bioprocessing Technology Institute
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ASK1 mediates Nur77 expression in T-cell receptor mediated thymocyte apoptosis
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Jianxin Huo,
Shengli Xu,
Kong-Peng Lam
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Cells
|
|
20 Feb 2020
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BMRC
|
Bioprocessing Technology Institute
|
Glycolysis and Oxidative Phosphorylation Play Critical Roles in Natural Killer Cell Receptor-Mediated Natural Killer Cell Functions
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Zixi Wang,
Di Guan,
Shu Wang,
Louis Yi Ann Chai,
Shengli Xu,
Kong-Peng Lam
|
Frontiers in Immunology
|
|
4 Jul 2019
|
BMRC
|
Bioprocessing Technology Institute
|
von Hippel-Lindau Protein Maintains Metabolic Balance to Regulate the Survival of Naive B Lymphocytes
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Shengli Xu,
Jianxin Huo,
Yuhan Huang,
Melissa Aw,
Shuwen Chen,
Shiya Mak,
Lian Yee Yip,
Ying Swan Ho,
Sze Wai Ng,
Andy Hee-Meng Tan,
Alison Lee,
Xijun Ou,
Kong-Peng Lam
|
iSCIENCE
|
|
10 Jun 2019
|
BMRC
|
Bioprocessing Technology Institute
|
Dok3–protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity
|
Jia Tong Loh,
Shengli Xu,
Jian Xin Huo,
Susana Soo-Yeon Kim,
Yue Wang,
Kong-Peng Lam
|
Journal of Clinical Investigation
|
|
4 Jun 2019
|
BMRC
|
Bioprocessing Technology Institute
|
FAIM: An Antagonist of Fas-Killing and Beyond
|
Jianxin Huo,
Shengli Xu,
Kong-Peng Lam
|
Cells
|
|
25 Feb 2019
|
BMRC
|
Bioprocessing Technology Institute
|
The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance IFN-β response
|
Susana Soo-Yeon Kim,
Lynette Sze,
Kong-Peng Lam
|
Journal of Biological Chemistry
|
|
13 Nov 2018
|
BMRC
|
Bioprocessing Technology Institute
|
Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells
|
Jia Tong Loh,
Thomas Jun Feng Lim,
Kyoko Ikumi,
Takuma Matoba,
Baptiste Janela,
Merry Gunawan,
Tatsuya Toyama,
Maegan Bunjamin,
Lai Guan Ng,
Michael Poidinger,
Akimichi Morita,
Florent Ginhoux,
Sayuri Yamazaki,
Kong-Peng Lam,
I-Hsin Su
|
iScience
|
|
2 Mar 2018
|
BMRC
|
Bioprocessing Technology Institute
|
Transcription factor YY1 is essential for iNKT cell development
|
Xijun Ou,
Jianxin Huo,
Yuhan Huang,
Yan-Feng Li,
Shengli Xu,
Kong-Peng Lam
|
Cellular & Molecular Immunology
|
|
27 Nov 2017
|
BMRC
|
Bioprocessing Technology Institute
|
Excessive interferon-α signaling in autoimmunity alters glycosphingolipid processing in B cells
|
Andy Hee-Meng Tan,
Arleen Sanny,
Sze-Wai Ng,
Ying-Swan Ho,
Nurhidayah Basri,
Alison Ping Lee,
Kong-Peng Lam
|
Journal of Autoimmunity
|
|
5 Feb 2016
|
BMRC
|
Bioprocessing Technology Institute
|
Loss of miR-182 affects B-cell extrafollicular antibody response
|
Yan-Feng Li,
Xijun Ou,
Shengli Xu,
Zi-Bing Jin,
Naoharu Iwai,
Kong-Peng Lam
|
Immunology
|
|
17 Apr 2015
|
BMRC
|
Bioprocessing Technology Institute
|
Mir-17~92 regulates bone marrow homing of plasma cells and production of immunoglobulin G 2c
|
Shengli Xu,
Xijun Ou,
Jianxin Huo,
Kristen Lim,
Yuhan Huang,
Sheena Chee,
Kong-Peng Lam
|
Nature Communications
|
|
25 Sep 2014
|
BMRC
|
Bioprocessing Technology Institute
|
Aberrant presentation of self-lipids by autoimmune B cells depletes peripheral iNKT cells
|
Andy Hee-Meng Tan,
William Pooi-Kat Chong,
Sze-Wai Ng,
Nurhidayah Basri,
Shengli Xu,
Kong-Peng Lam
|
Cell Reports
|
|
29 Aug 2014
|
BMRC
|
Bioprocessing Technology Institute
|
Bruton's tyrosine kinase and protein kinase C µ are required for TLR7/9-induced IKKα and IRF-1 activation and interferon-β production in conventional dendritic cells
|
Yan-Feng Li,
Koon-Guan Lee,
Xijun Ou,
Kong-Peng Lam
|
PLOS ONE
|
|
30 Jun 2014
|
BMRC
|
Bioprocessing Technology Institute
|
Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool
|
Yan-Feng Li,
Shengli Xu,
Xijun Ou,
Kong-Peng Lam
|
Nature Communications
|
|
12 May 2010
|
BMRC
|
Singapore Immunology Network
|
Macrophage polarization to a unique phenotype driven by B cells
|
Siew-Cheng Wong,
Anne-Laure Puaux,
Manesh Chittezhath,
Irina Shalova,
Tasneem S. Kajiji,
Xiaojie Wang,
Jean-Pierre Abastado,
Kong-Peng Lam,
Subhra K. Biswas
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European Journal of Immunology
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