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31 Oct 2023
BMRC
Singapore Immunology Network
DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11
Jia Tong Loh,
Joey Kay Hui Teo,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Anand Kumar Andiappan,
Hong-Hwa Lim,
Kong-Peng Lam
Science Signaling
11 Aug 2023
BMRC
Singapore Immunology Network
Natural Killer Cell Engagers (NKCEs): a new frontier in cancer immunotherapy
Minchuan Zhang,
Kong-Peng Lam,
Shengli Xu
Frontiers in Immunology
9 Jun 2023
BMRC
Singapore Immunology Network
Identification of a novel mitochondria-localized LKB1 variant required for the regulation of the oxidative stress response
Ivan Tan,
Shengli Xu,
Jianxin Huo,
Yuhan Huang,
Hong-Hwa Lim,
Kong-Peng Lam
Journal of Biological Chemistry
26 Apr 2023
BMRC
Singapore Immunology Network
Harnessing novel strategies and cell types to overcome immune tolerance during adoptive cell therapy in cancer
Shi Yong Neo,
Shengli Xu,
Joni Chong,
Kong-Peng Lam,
Jing Wu
Journal for ImmunoTherapy of Cancer
9 Jun 2022
BMRC
Singapore Immunology Network
Development of a T cell-redirecting bispecific antibody targeting B-cell maturation antigen for the suppression of multiple myeloma cell growth
Jianxin Huo,
Yuhan Huang,
Ziying Zheng,
Xin Ni Tay,
Farouq Bin Mahfut,
Wei Zhang,
Kong-Peng Lam,
Yuansheng Yang,
Shengli Xu
Antibody Therapeutics
8 Mar 2022
BMRC
Institute of Molecular and Cell Biology
Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer
Vikrant Kumar,
Kalpana Ramnarayanan,
Raghav Sundar,
Nisha Padmanabhan,
Supriya Srivastava,
Mayu Koiwa,
Tadahito Yasuda,
Vivien Koh,
Kie Kyon Huang,
Su Ting Tay,
Shamaine Wei Ting Ho,
Angie Lay Keng Tan,
Takatsugu Ishimoto,
Guowei Kim,
Asim Shabbir,
Qingfeng Chen,
Biyan Zhang,
Shengli Xu,
Kong-Peng Lam,
Huey Yew Jeffrey Lum,
Ming Teh,
Wei Peng Yong,
Jimmy Bok Yan So,
Patrick Tan
Cancer Discovery
15 Feb 2022
BMRC
Institute of Molecular and Cell Biology
Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
Jia Tong Loh,
Bin Zhang,
Joey Kay Hui Teo,
Ruenn Chai Lai,
Andre Boon Hwa Choo,
Kong-Peng Lam,
Sai Kiang Lim
Cytotherapy
8 Feb 2022
BMRC
Singapore Immunology Network
The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement
Gui-Xin Ruan,
Yuxing Li,
Wenjing Chen,
Hengjun Huang,
Rui Zhang,
Changxu Chen,
Kong-Peng Lam,
Shengli Xu,
Xijun Ou
Cell Reports
7 May 2021
BMRC
Bioprocessing Technology Institute
Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response
Koon-Guan Lee,
Susana Soo-Yeon Kim,
Lin Kui,
Dominic Chih-Cheng Voon,
Marjorie Mauduit,
Pradeep Bist,
Xuezhi Bi,
Natasha Ann Pereira,
Chengcheng Liu,
Bindu Sukumaran,
Laurent Renia,
Yoshiaki Ito,
Kong-Peng Lam
Cell Reports
30 Apr 2021
BMRC
Singapore Immunology Network
Bruton’s tyrosine kinase regulates gut immune homeostasis through attenuating Th1 response
Di Guan,
Zixi Wang,
Jianxin Huo,
Shengli Xu,
Kong-Peng Lam
Cell Death & Disease
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