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27 Mar 2023
BMRC
Genome Institute of Singapore
Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study
Peh Joo Ho,
Iain Beehuat Tan,
Dawn Qingqing Chong,
Chiea Chuen Khor,
Jian-Min Yuan,
Woon-Puay Koh,
Rajkumar Dorajoo,
Jingmei Li
eLife
26 Apr 2022
BMRC
Genome Institute of Singapore
Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification
Peh Joo Ho,
Weang Kee Ho,
Alexis J. Khng,
Yen Shing Yeoh,
Benita Kiat-Tee Tan,
Ern Yu Tan,
Geok Hoon Lim,
Su-Ming Tan,
Veronique Kiak Mien Tan,
Cheng-Har Yip,
Nur-Aishah Mohd-Taib,
Fuh Yong Wong,
Elaine Hsuen Lim,
Joanne Ngeow,
Wen Yee Chay,
Lester Chee Hao Leong,
Wei Sean Yong,
Chin Mui Seah,
Siau Wei Tang,
Celene Wei Qi Ng,
Zhiyan Yan,
Jung Ah Lee,
Kartini Rahmat,
Tania Islam,
Tiara Hassan,
Mei-Chee Tai,
Chiea Chuen Khor,
Jian-Min Yuan,
Woon-Puay Koh,
Xueling Sim,
Alison M. Dunning,
Manjeet K. Bolla,
Antonis C. Antoniou,
Soo-Hwang Teo,
Jingmei Li,
Mikael Hartman
BMC Medicine
17 Oct 2019
BMRC
Genome Institute of Singapore
Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore
Degang Wu,
Jinzhuang Dou,
Xiaoran Chai,
Claire Bellis,
Andreas Wilm,
Chih Chuan Shih,
Wendy Wei Jia Soon,
Nicolas Bertin,
Clarabelle Bitong Lin,
Chiea Chuen Khor,
Michael DeGiorgio,
Shanshan Cheng,
Li Bao,
Neerja Karnani,
William Ying Khee Hwang,
Sonia Davila,
Patrick Tan,
Asim Shabbir,
Angela Moh,
Eng-King Tan,
Jia Nee Foo,
Luih Ling Goh,
Khai Pang Leong,
Roger S. Y. Foo,
Carolyn Su Ping Lam,
Arthur Mark Richards,
Ching-Yu Cheng,
Tin Aung,
Tien Yin Wong,
Huck Hui Ng,
Jianjun Liu,
Chaolong Wang
Cell
7 Aug 2014
BMRC
Institute of Molecular and Cell Biology
Genetic variants of inducible costimulator are associated with allergic asthma susceptibility
Rachel A. Myers,
Bernett Lee,
Maartje A. Nieuwenhuis,
Alessandra Nardin,
Choon-Sik Park,
Hyoung Doo Shin,
Jeong-Hyun Kim,
Anand Kumar Andiappan,
Sriram Narayanan,
Harm-Jan Westra,
Lude Franke,
Tonu Esko,
Andres Metspalu,
Yik-Ying Teo,
Seang Mei Saw,
Chiea Chuen Khor,
Jianjun Liu,
Gerard H. Koppelman,
Dirkje S. Postma,
Michael Poidinger,
John E. Connolly,
De Yun Wang,
Olaf Rotzschke,
Maria A. Curotto de Lafaille,
Fook Tim Chew
Journal of Allergy and Clinical Immunology
17 Jun 2014
BMRC
Genome Institute of Singapore
2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy
Dieter Flesch-Janys,
Petra Seibold,
Anja Rudolph,
Graham G. Giles,
Laura Baglietto,
Gianluca Severi,
Christopher A. Haiman,
Brian E. Henderson,
Fredrick Schumacher,
Loic Le Marchand,
Vessela Kristensen,
Grethe I. Grenaker Alnæs,
Anne-Lise Borresen-Dale,
Silje Nord,
Robert Winqvist,
Yi Li,
Ute Hamann,
Diana Torres,
Hans U. Ulmer,
Thomas Rüdiger,
Chen-Yang Shen,
Chia-Ni Hsiung,
Katri Pylkäs,
Arja Jukkola-Vuorinen,
Mervi Grip,
Irene L. Andrulis,
Julia A. Knight,
Gord Glendon,
Sandrine Tchatchou,
Peter Devilee,
Robert Tollenaar,
Caroline Seynaeve,
Maartje Hooning,
Mieke Kriege,
Antoinette Hollestelle,
Ans van den Ouweland,
Nur Aishah Mohd Taib,
Pei-Ei Wu,
Shou-Tung Chen,
Soo Hwang Teo,
Cheng Har Yip,
Gwo Fuang Ho,
Keitaro Matsuo,
Hidemi Ito,
Hiroji Iwata,
Kazuo Tajima,
Daehee Kang,
Ji-Yeob Choi,
Sue K. Park,
Keun-Young Yoo,
Tom Maishman,
William J. Tapper,
Alison Dunning,
Mitul Shah,
Robert Luben,
Judith Brown,
Chiea Chuen Khor,
Diana M. Eccles,
Heli Nevanlinna,
Douglas Easton,
Keith Humphreys,
Jianjun Liu,
Per Hall,
Kamila Czene,
Sara Margolin,
Arto Mannermaa,
Veli-Matti Kosma,
Jaana M. Hartikainen,
Vesa Kataja,
Georgia Chenevix-Trench,
kConFab Investigators,
Kelly-Anne Phillips,
Laura J. Van ‘t Veer,
Sten Cornelissen,
Emiel Rutgers,
Jingmei Li,
Linda S. Lindström,
Jia N. Foo,
Sajjad Rafiq,
Melissa C. Southey,
Carmel Apicella,
Gillian S. Dite,
John L. Hopper,
Peter A. Fasching,
Lothar Haeberle,
Arif B. Ekici,
Matthias W. Beckmann,
Carl Blomqvist,
Taru A. Muranen,
Kristiina Aittomaki,
Annika Lindblom,
Marjanka K. Schmidt,
Paul D. P. Pharoah,
Kyriaki Michailidou,
Joe Dennis,
Manjeet K. Bolla,
Qin Wang,
Sue-Anne McLachlan,
Diether Lambrechts,
Bernard Thienpont,
Ann Smeets,
Hans Wildiers,
Jenny Chang-Claude
Nature Communications
6 Mar 2014
BMRC
Genome Institute of Singapore
ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma
Monisha E. Nongpiur,
Chiea Chuen Khor,
Hongyan Jia,
Belinda K. Cornes,
Li-Jia Chen,
Chunyan Qiao,
K. Saidas Nair,
Ching-Yu Cheng,
Liang Xu,
Ronnie George,
Do Tan,
Khaled Abu-Amero,
Shamira A. Perera,
Mineo Ozaki,
Takanori Mizoguchi,
Yasuo Kurimoto,
Sancy Low,
Liza-Sharmini A. Tajudin,
Ching-Lin Ho,
Clement C. Y. Tham,
Ileana Soto,
Paul T. K. Chew,
Hon-Tym Wong,
Balekudaru Shantha,
Masako Kuroda,
Essam A. Osman,
Guangxian Tang,
Sujie Fan,
Hailin Meng,
Hua Wang,
Bo Feng,
Victor H. K. Yong,
Serena M. L. Ting,
Yang Li,
Ya-Xing Wang,
Zheng Li,
Raghavan Lavanya,
Ren-Yi Wu,
Ying-Feng Zheng,
Daniel H. Su,
Seng-Chee Loon,
R. Rand Allingham,
Michael A. Hauser,
Nagaswamy Soumittra,
Vedam L. Ramprasad,
Naushin Waseem,
Azhany Yaakub,
Kee-Seng Chia,
Govindasamy Kumaramanickavel,
Tina T. Wong,
Alicia C. How,
Tran Nguyen Bich Chau,
Cameron P. Simmons,
Jin-Xin Bei,
Yi-Xin Zeng,
Shomi S. Bhattacharya,
Mingzhi Zhang,
Donald T. Tan,
Yik-Ying Teo,
Saleh A. Al-Obeidan,
Do Nhu Hon,
E-Shyong Tai,
Seang-Mei Saw,
Paul J. Foster,
Lingam Vijaya,
Jost B. Jonas,
Tien-Yin Wong,
Simon W. M. John,
Chi-Pui Pang,
Eranga N. Vithana,
Ningli Wang,
Tin Aung,
Janey L. Wiggs
PLoS Genetics
24 Jan 2014
BMRC
Genome Institute of Singapore
Impact of Measurement Error on Testing Genetic Association with Quantitative Traits
Xiang Li,
Jiemin Liao,
Tien-Yin Wong,
Jie Jin Wang,
Chiea Chuen Khor,
E. Shyong Tai,
Tin Aung,
Yik-Ying Teo,
Ching-Yu Cheng,
Dmitri Zaykin
PLoS ONE
30 Aug 2013
BMRC
Genome Institute of Singapore
Replication and Meta-Analysis of GWAS Identified Susceptibility Loci in Kawasaki Disease Confirm the Importance of B Lymphoid Tyrosine Kinase (BLK) in Disease Susceptibility
Chia-Jung Chang,
Ho-Chang Kuo,
Jeng-Sheng Chang,
Jong-Keuk Lee,
Fuu-Jen Tsai,
Chiea Chuen Khor,
Li-Ching Chang,
Shih-Ping Chen,
Tai-Ming Ko,
Yi-Min Liu,
Ying-Ju Chen,
Young Mi Hong,
Gi Young Jang,
Martin L. Hibberd,
Taco Kuijpers,
David Burgner,
Michael Levin,
Jane C. Burns,
Sonia Davila,
Yuan-Tsong Chen,
Chien-Hsiun Chen,
Jer-Yuarn Wu,
Yi-Ching Lee
PLoS ONE
21 Aug 2013
BMRC
Genome Institute of Singapore
Combined genotype and haplotype tests for region-based association studies
(Pending publish)
Sergii Zakharov,
Tien Yin Wong,
Tin Aung,
Eranga Nishanthie Vithana,
Chiea Chuen Khor,
Agus Salim,
Anbupalam Thalamuthu
BMC Genomics
19 Aug 2013
BMRC
Genome Institute of Singapore
Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia
(Pending publish)
Veluchamy A. Barathi,
Fan Qiao,
Isao Nakata,
Kenji Yamashiro,
Xin Zhou,
Pancy O. S. Tam,
Ching-Yu Cheng,
E. Shyong Tai,
Eranga N. Vithana,
Tin Aung,
Masahiro Miyake,
Li Jia Chen,
Yi Shi,
Yik-Ying Teo,
Tien-Yin Wong,
Muka Moriyama,
Kyoko Ohno-Matsui,
Manabu Mochizuki,
Fumihiko Matsuda,
Rita Y. Y. Yong,
Eric P. H. Yap,
Zhenglin Yang,
Chi Pui Pang,
Seang-Mei Saw,
Nagahisa Yoshimura,
Chiea Chuen Khor
Human Molecular Genetics
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