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Publication date Communities Collections Article title Author(s) Journal/Conference
27 Aug 2020 BMRC Bioprocessing Technology Institute Clustering and Curation of Electropherograms: An Efficient Method for Analysing Large Cohorts of Glycomic Profiles in Tracking the Effects of Multivariate Parameters in Bioprocessing Operations Walsh Ian, Choo Matthew S F, Chiin Sim Lyn, Mak Amelia, Tay Shi Jie, Rudd Pauline M, Yuansheng Yang, Choo Andre, Ying Swan Ho, Nguyen-Khuong Terry Beilstein Journal of Organic Chemistry
11 Aug 2020 BMRC Bioprocessing Technology Institute A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins Kae Hwan Sim, Lillian Chia-Yi Liu, Hwee Tong Tan, Kelly Tan, Daniel Ng, Wei Zhang, Yuansheng Yang, Stephen Tate, Xuezhi Bi Scientific Data
2 Aug 2018 BMRC Bioprocessing Technology Institute Conservation of oncofetal antigens on human embryonic stem cells enables discovery of monoclonal antibodies against cancer Heng Liang Tan, Charlene Yong, Bao Zhu Tan, Wey Jia Fong, Jayanthi Padmanabhan, Angela Chin, Vanessa Ding, Ally Lau, Lu Zheng, Xuezhi Bi, Yuansheng Yang, Andre Choo Scientific Reports
10 Jan 2018 BMRC Bioprocessing Technology Institute Targeting of embryonic annexin A2 expressed on ovarian and breast cancer by the novel monoclonal antibody 2448 Simeon Cua, Heng Liang Tan, Wey Jia Fong, Angela Chin, Ally Lau, Vanessa Ding, Zhiwei Song, Yuansheng Yang, Andre Choo Oncotarget
25 Jan 2016 BMRC Bioprocessing Technology Institute Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs Peiqing Zhang, Susanto Woen, Tianhua Wang, Brian Liau, Sophie Zhao, Chen Chen, Yuansheng Yang, Zhiwei Song, Mark R. Wormald, Chuanfei Yu, Pauline M. Rudd Drug Discovery Today
19 Dec 2015 BMRC Bioprocessing Technology Institute Advance chromatin extraction improves capture performance of protein A affinity chromatography Rui Nian, Wei Zhang, Lihan Tan, Jeremy Lee, Xuezhi Bi, Yuansheng Yang, Hui Theng Gan, Pete Gagnon Journal of Chromatography A
16 Oct 2015 BMRC Bioprocessing Technology Institute Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies Kah Fai Chan, Wahyu Shahreel, Corrine Wan, Gavin Teo, Noor Hayati, Shi Jie Tay, Wen Han Tong, Yuansheng Yang, Pauline M. Rudd, Peiqing Zhang, Zhiwei Song Biotechnology Journal
12 Oct 2015 BMRC Bioprocessing Technology Institute Impact of Using Different Promoters and Matrix Attachment Regions on Recombinant Protein Expression Level and Stability in Stably Transfected CHO Cells Steven C. L. Ho, Mariati, Jessna H. M. Yeo, Shiyi Goh Fang, Yuansheng Yang Molecular Biotechnology
8 Jul 2015 BMRC Bioprocessing Technology Institute Non-immunospecific association of immunoglobulin G with chromatin during elution from protein A inflates host contamination, aggregate content, and antibody loss Pete Gagnon, Rui Nian, Yuansheng Yang, Qiaohui Yang, Chiew Ling Lim Journal of Chromatography A
28 Mar 2015 BMRC Bioprocessing Technology Institute Characterization of DNA in cell culture supernatant by fluorescence-detection size-exclusion chromatography Lihan Tan, Veronica Yeo, Yuansheng Yang, Pete Gagnon Analytical and Bioanalytical Chemistry
11 Mar 2015 BMRC Bioprocessing Technology Institute Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells Jake Chng, Tianhua Wang, Rui Nian, Ally Lau, Kong Meng Hoi, Steven C. L. Ho, Peter Gagnon, Xuezhi Bi, Yuansheng Yang mAbs
6 Mar 2015 BMRC Bioprocessing Technology Institute IgG aggregation mechanism for CHO cell lines expressing excess heavy chains and strategies to reduce the aggregates Steven C. L. Ho, Tianhua Wang, Zhiwei Song, Yuansheng Yang Molecular Biotechnology
23 Feb 2015 BMRC Bioprocessing Technology Institute Optimization of Heavy Chain and Light Chain Signal Peptides for High Level Expression of Therapeutic Antibodies in CHO Cells Ryan Haryadi, Steven Ho, Yee Jiun Kok, Helen X. Pu, Lu Zheng, Natasha A. Pereira, Bin Li, Xuezhi Bi, Lin-Tang Goh, Yuansheng Yang, Zhiwei Song PLOS ONE
25 Nov 2014 BMRC Bioprocessing Technology Institute Chromatin-Mediated Depression of Fractionation Performance on Electronegative Multimodal Chromatography Media, its Prevention, and Ramifications for Purification of Immunoglobulin G Pete Gagnon, Rui Nian, Lihan Tan, Jason Cheong, Veronica Yeo, Yuansheng Yang, Hui Theng Gan Journal of Chromatography A
23 Jul 2014 BMRC Bioprocessing Technology Institute Toward stable gene expression in CHO cells Mariati Mariati, Esther Y.C Koh, Jessna H.M. Yeo, Steven C.L. Ho, Yuansheng Yang Bioengineered
23 Jun 2014 BMRC Bioprocessing Technology Institute Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells Wan Ping Loh, Bernard Loo, Peiqing Zhang, Dong-Yup Lee, Yuansheng Yang, Kong Peng Lam, Lihan Zhou Biotechnology Journal
10 May 2014 BMRC Bioprocessing Technology Institute Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells Mariati Mariati, Jessna H. M. Yeo, Esther Y. C. Koh, Steven C. L. Ho, Yuansheng Yang Biotechnology Progress
16 Apr 2014 BMRC Bioprocessing Technology Institute Identifying and engineering promoters for high level and sustainable therapeutic recombinant protein production in cultured mammalian cells Steven C. L. Ho, Yuansheng Yang Biotechnology Letters
11 Mar 2014 BMRC Bioprocessing Technology Institute Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance Pete Gagnon, Rui Nian, Jeremy Lee, Lihan Tan, Sarah Maria Abdul Latiff, Chiew Ling Lim, Cindy Chuah, Xuezhi Bi, Yuansheng Yang, Wei Zhang, Hui Theng Gan Journal of Chromatography A
9 Dec 2013 BMRC Bioprocessing Technology Institute An Internal Ribosome Entry Site (IRES) Mutant Library for Tuning Expression Level of Multiple Genes in Mammalian Cells Esther Y. C. Koh, Steven C. L. Ho, Mariati Mariati, Zhiwei Song, Xuezhi Bi, Muriel Bardor, Yuansheng Yang PLoS ONE