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Publication date Communities Collections Article title Author(s) Journal/Conference
22 Apr 2023 BMRC Bioprocessing Technology Institute Enhancing pharmacokinetic and pharmacodynamic properties of recombinant therapeutic proteins by manipulation of sialic acid content Sean Chia, Shi Jie Tay, Zhiwei Song, Yuansheng Yang, Ian Walsh, Kuin Tian Pang Biomedicine & Pharmacotherapy
25 Jan 2023 BMRC Bioprocessing Technology Institute Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step Serene W. Chen, Zi Ying Zheng, Farouq Bin Mahfut, Yuansheng Yang, Masahiro Ogino, Kazuo Okada, Kohei Sato, Wei Zhang PLOS ONE
4 Jul 2022 BMRC Bioprocessing Technology Institute Excellent removal of knob-into-hole bispecific antibody byproducts and impurities in a single-capture chromatography Serene W. Chen, Kong Meng Hoi, Farouq Bin Mahfut, Yuansheng Yang, Wei Zhang Bioresources and Bioprocessing
27 Aug 2020 BMRC Bioprocessing Technology Institute Clustering and Curation of Electropherograms: An Efficient Method for Analysing Large Cohorts of Glycomic Profiles in Tracking the Effects of Multivariate Parameters in Bioprocessing Operations Walsh Ian, Choo Matthew S F, Chiin Sim Lyn, Mak Amelia, Tay Shi Jie, Rudd Pauline M, Yuansheng Yang, Choo Andre, Ying Swan Ho, Nguyen-Khuong Terry Beilstein Journal of Organic Chemistry
11 Aug 2020 BMRC Bioprocessing Technology Institute A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins Kae Hwan Sim, Lillian Chia-Yi Liu, Hwee Tong Tan, Kelly Tan, Daniel Ng, Wei Zhang, Yuansheng Yang, Stephen Tate, Xuezhi Bi Scientific Data
2 Aug 2018 BMRC Bioprocessing Technology Institute Conservation of oncofetal antigens on human embryonic stem cells enables discovery of monoclonal antibodies against cancer Heng Liang Tan, Charlene Yong, Bao Zhu Tan, Wey Jia Fong, Jayanthi Padmanabhan, Angela Chin, Vanessa Ding, Ally Lau, Lu Zheng, Xuezhi Bi, Yuansheng Yang, Andre Choo Scientific Reports
10 Jan 2018 BMRC Bioprocessing Technology Institute Targeting of embryonic annexin A2 expressed on ovarian and breast cancer by the novel monoclonal antibody 2448 Simeon Cua, Heng Liang Tan, Wey Jia Fong, Angela Chin, Ally Lau, Vanessa Ding, Zhiwei Song, Yuansheng Yang, Andre Choo Oncotarget
25 Jan 2016 BMRC Bioprocessing Technology Institute Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs Peiqing Zhang, Susanto Woen, Tianhua Wang, Brian Liau, Sophie Zhao, Chen Chen, Yuansheng Yang, Zhiwei Song, Mark R. Wormald, Chuanfei Yu, Pauline M. Rudd Drug Discovery Today
19 Dec 2015 BMRC Bioprocessing Technology Institute Advance chromatin extraction improves capture performance of protein A affinity chromatography Rui Nian, Wei Zhang, Lihan Tan, Jeremy Lee, Xuezhi Bi, Yuansheng Yang, Hui Theng Gan, Pete Gagnon Journal of Chromatography A
16 Oct 2015 BMRC Bioprocessing Technology Institute Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies Kah Fai Chan, Wahyu Shahreel, Corrine Wan, Gavin Teo, Noor Hayati, Shi Jie Tay, Wen Han Tong, Yuansheng Yang, Pauline M. Rudd, Peiqing Zhang, Zhiwei Song Biotechnology Journal