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Publication date Communities Collections Article title Author(s) Journal/Conference
27 Nov 2025 BMRC Bioprocessing Technology Institute Optimizing co-expression strategies for the simultaneous display and secretion of monoclonal antibodies in CHO cells Jessica P. Z. Ng, Mariati Mariati, Han Kee Ong, Xuezhi Bi, Matthew Chang, Yuansheng Yang Scientific Reports
28 Apr 2025 BMRC Bioprocessing Technology Institute A Targeted Integration-Based CHO Cell Platform for Simultaneous Antibody Display and Secretion Jessica P. Z. Ng, Mariati Mariati, Jiawu Bi, Matthew Wook Chang, Yuansheng Yang Antibodies
29 Nov 2024 BMRC Singapore Immunology Network Development of BCMA-Targeted Bispecific Natural Killer Cell Engagers for Multiple Myeloma Treatment Minchuan Zhang, Han Ping Loh, Shiyi Goh Fang, Yuansheng Yang, Kong-Peng Lam, Shengli Xu Antibodies
18 Oct 2024 BMRC Bioprocessing Technology Institute Thermal and pH stress dictate distinct mechanisms of monoclonal antibody aggregation Kong Meng Hoi, Kuin Tian Pang, Corrine Wan, Zi Ying Zheng, Beiying Qiu, Yuansheng Yang, Zhang Wei, Ying Swan Ho, Ian Walsh, Sean Chia International Journal of Biological Macromolecules
22 Jul 2024 BMRC Bioprocessing Technology Institute Effects of molecule hydrophobicity and structural flexibility of appended bispecific antibody on Protein A chromatography Xinhui Wang, Nattha Ingavat, Jia Min Liew, Nuruljannah Dzulkiflie, Han Ping Loh, Yee Jiun Kok, Xuezhi Bi, Yuansheng Yang, Wei Zhang Journal of Chromatography A
13 Dec 2023 BMRC Bioprocessing Technology Institute Harnessing ceramic hydroxyapatite as an effective polishing strategy to remove product- and process-related impurities in bispecific antibody purification Nattha Ingavat, Xinhui Wang, Jia Min Liew, Farouq Bin Mahfut, Ka Pui But, Yee Jiun Kok, Xuezhi Bi, Yuansheng Yang, Kobayashi Shintaro, Maria Tsoumpra, Wei Zhang Bioresources and Bioprocessing
20 Sep 2023 BMRC Bioprocessing Technology Institute Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform Ngan T. B. Nguyen, Hau Wan Leung, Kuin Tian Pang, Shi Jie Tay, Ian Walsh, Andre B. H. Choo, Yuansheng Yang Scientific Reports
5 Jul 2023 BMRC Bioprocessing Technology Institute Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies Han Ping Loh, Farouq Bin Mahfut, Serene W Chen, Yuhan Huang, Jianxin Huo, Wei Zhang, Kong Peng Lam, Shengli Xu, Yuansheng Yang mAbs
22 Apr 2023 BMRC Bioprocessing Technology Institute Enhancing pharmacokinetic and pharmacodynamic properties of recombinant therapeutic proteins by manipulation of sialic acid content Sean Chia, Shi Jie Tay, Zhiwei Song, Yuansheng Yang, Ian Walsh, Kuin Tian Pang Biomedicine & Pharmacotherapy
25 Jan 2023 BMRC Bioprocessing Technology Institute Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step Serene W. Chen, Zi Ying Zheng, Farouq Bin Mahfut, Yuansheng Yang, Masahiro Ogino, Kazuo Okada, Kohei Sato, Wei Zhang PLOS ONE