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Publication date Communities Collections Article title Author(s) Journal/Conference
13 Dec 2023 BMRC Bioprocessing Technology Institute Harnessing ceramic hydroxyapatite as an effective polishing strategy to remove product- and process-related impurities in bispecific antibody purification Nattha Ingavat, Xinhui Wang, Jia Min Liew, Farouq Bin Mahfut, Ka Pui But, Yee Jiun Kok, Xuezhi Bi, Yuansheng Yang, Kobayashi Shintaro, Maria Tsoumpra, Wei Zhang Bioresources and Bioprocessing
20 Sep 2023 BMRC Bioprocessing Technology Institute Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform Ngan T. B. Nguyen, Hau Wan Leung, Kuin Tian Pang, Shi Jie Tay, Ian Walsh, Andre B. H. Choo, Yuansheng Yang Scientific Reports
5 Jul 2023 BMRC Bioprocessing Technology Institute Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies Han Ping Loh, Farouq Bin Mahfut, Serene W Chen, Yuhan Huang, Jianxin Huo, Wei Zhang, Kong Peng Lam, Shengli Xu, Yuansheng Yang mAbs
22 Apr 2023 BMRC Bioprocessing Technology Institute Enhancing pharmacokinetic and pharmacodynamic properties of recombinant therapeutic proteins by manipulation of sialic acid content Sean Chia, Shi Jie Tay, Zhiwei Song, Yuansheng Yang, Ian Walsh, Kuin Tian Pang Biomedicine & Pharmacotherapy
25 Jan 2023 BMRC Bioprocessing Technology Institute Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step Serene W. Chen, Zi Ying Zheng, Farouq Bin Mahfut, Yuansheng Yang, Masahiro Ogino, Kazuo Okada, Kohei Sato, Wei Zhang PLOS ONE
4 Jul 2022 BMRC Bioprocessing Technology Institute Excellent removal of knob-into-hole bispecific antibody byproducts and impurities in a single-capture chromatography Serene W. Chen, Kong Meng Hoi, Farouq Bin Mahfut, Yuansheng Yang, Wei Zhang Bioresources and Bioprocessing
9 Jun 2022 BMRC Singapore Immunology Network Development of a T cell-redirecting bispecific antibody targeting B-cell maturation antigen for the suppression of multiple myeloma cell growth Jianxin Huo, Yuhan Huang, Ziying Zheng, Xin Ni Tay, Farouq Bin Mahfut, Wei Zhang, Kong-Peng Lam, Yuansheng Yang, Shengli Xu Antibody Therapeutics
23 Feb 2021 BMRC Singapore Immunology Network IL-10 Enhances Human Natural Killer Cell Effector Functions via Metabolic Reprogramming Regulated by mTORC1 Signaling Zixi Wang, Di Guan, Jianxin Huo, Subhra K. Biswas, Yuhan Huang, Yuansheng Yang, Shengli Xu, Kong-Peng Lam Frontiers in Immunology
27 Aug 2020 BMRC Bioprocessing Technology Institute Clustering and Curation of Electropherograms: An Efficient Method for Analysing Large Cohorts of Glycomic Profiles in Tracking the Effects of Multivariate Parameters in Bioprocessing Operations Walsh Ian, Choo Matthew S F, Chiin Sim Lyn, Mak Amelia, Tay Shi Jie, Rudd Pauline M, Yuansheng Yang, Choo Andre, Ying Swan Ho, Nguyen-Khuong Terry Beilstein Journal of Organic Chemistry
11 Aug 2020 BMRC Bioprocessing Technology Institute A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins Kae Hwan Sim, Lillian Chia-Yi Liu, Hwee Tong Tan, Kelly Tan, Daniel Ng, Wei Zhang, Yuansheng Yang, Stephen Tate, Xuezhi Bi Scientific Data