Genome Institute of Singapore

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Publication date Article title Author(s)
24 Oct 2025 Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer Zhengwei Wu, Zhenxun Wang, Seow Qi Ng, Jessica Alice Lidster, Paul Schwerd-Kleine, Zi Jin Cheryl Phua, Kai Lay Esther Peh, Yin Ying Ho, Ju Yuan, S. Shathishwaran, Xun Hui Yeo, Ying Zhang, Yui Hei Jasper Chiu, Li Yieng Eunice Lau, Tony Kiat Hon Lim, Angela Takano, Eng Huat Tan, Anders Jacobsen Skanderup, Vinay Tergaonkar, Weiping Han, Ying Swan Ho, Daniel Shao Weng Tan, Wai Leong Tam
16 Oct 2025 Read-level DNA methylation deconvolution enhances circulating tumor DNA detection Ting Qi, Lakshmi Narayanan Lakshmanan, Yuwei Yang, Ying Zhou, Min Pan, Anders Jacobsen Skanderup, Qinyu Ge
11 Sep 2025 Emerging principles and models of human primordial germ cell development Navin B. Ramakrishna, João Pedro Alves-Lopes, Wolfram H. Gruhn
28 Aug 2025 Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human body Minghao Chia, Amanda Hui Qi Ng, Aarthi Ravikrishnan, Ahmad Nazri Mohamed Naim, Stephen Wearne, John Common, Niranjan Nagarajan
30 Jul 2025 Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning Mauricio Perez, Michiko Kimoto, Priscilla Rajakumar, Chayaporn Suphavilai, Rafael Peres da Silva, Hui Pen Tan, Nicholas Ting Xun Ong, Hannah Nicholas, Ichiro Hirao, Wei Leong Chew, Niranjan Nagarajan
10 Apr 2025 FBXO22 deficiency defines a pleiotropic syndrome of growth restriction and multi-system anomalies associated with a unique epigenetic signature Navin B. Ramakrishna, Umar Bin Mohamad Sahari, Yoshikazu Johmura, Nur Ain Ali, Malak Alghamdi, Peter Bauer, Suliman Khan, Natalia Ordoñez, Mariana Ferreira, Jorge Pinto Basto, Fowzan S. Alkuraya, Eissa Ali Faqeih, Mari Mori, Naif A.M. Almontashiri, Aisha Al Shamsi, Gehad ElGhazali, Hala Abu Subieh, Mode Al Ojaimi, Ayman W. El-Hattab, Said Ahmed Said Al-Kindi, Nadia Alhashmi, Fahad Alhabshan, Abdulaziz Al Saman, Hala Tfayli, Mariam Arabi, Simone Khalifeh, Alan Taylor, Majid Alfadhel, Ruchi Jain, Shruti Sinha, Shruti Shenbagam, Revathy Ramachandran, Umut Altunoglu, Anju Jacob, Nandu Thalange, Mireille El Bejjani, Arnaud Perrin, Jay W. Shin, Almundher Al-Maawali, Azza Al-Shidhani, Amna Al-Futaisi, Fatma Rabea, Ikram Chekroun, Mohamed A. Almarri, Tomohiko Ohta, Makoto Nakanishi, Alawi Alsheikh-Ali, Fahad R. Ali, Aida M. Bertoli-Avella, Bruno Reversade, Ahmad Abou Tayoun
19 Mar 2025 Asian diversity in human immune cells Kian Hong Kock, Le Min Tan, Kyung Yeon Han, Yoshinari Ando, Damita Jevapatarakul, Ankita Chatterjee, Quy Xiao Xuan Lin, Eliora Violain Buyamin, Radhika Sonthalia, Deepa Rajagopalan, Yoshihiko Tomofuji, Shvetha Sankaran, Mi-So Park, Mai Abe, Juthamard Chantaraamporn, Seiko Furukawa, Supratim Ghosh, Gyo Inoue, Miki Kojima, Tsukasa Kouno, Jinyeong Lim, Keiko Myouzen, Sarintip Nguantad, Jin-Mi Oh, Nirmala Arul Rayan, Sumanta Sarkar, Akari Suzuki, Narita Thungsatianpun, Prasanna Nori Venkatesh, Jonathan Moody, Masahiro Nakano, Ziyue Chen, Chi Tian, Yuntian Zhang, Yihan Tong, Crystal T.Y. Tan, Anteneh Mehari Tizazu, Marie Loh, You Yi Hwang, Roger C. Ho, Anis Larbi, Tze Pin Ng, Hong-Hee Won, Fred A. Wright, Alexandra-Chloé Villani, Jong-Eun Park, Murim Choi, Boxiang Liu, Arindam Maitra, Manop Pithukpakorn, Bhoom Suktitipat, Kazuyoshi Ishigaki, Yukinori Okada, Kazuhiko Yamamoto, Piero Carninci, John C. Chambers, Chung-Chau Hon, Ponpan Matangkasombut, Varodom Charoensawan, Partha P. Majumder, Jay W. Shin, Woong-Yang Park, Shyam Prabhakar
13 Mar 2025 A systematic benchmark of Nanopore long-read RNA sequencing for transcript-level analysis in human cell lines Ying Chen, Nadia M. Davidson, Yuk Kei Wan, Fei Yao, Yan Su, Hasindu Gamaarachchi, Andre Sim, Harshil Patel, Hwee Meng Low, Christopher Hendra, Laura Wratten, Christopher Hakkaart, Chelsea Sawyer, Viktoriia Iakovleva, Puay Leng Lee, Lixia Xin, Hui En Vanessa Ng, Jia Min Loo, Xuewen Ong, Hui Qi Amanda Ng, Jiaxu Wang, Wei Qian Casslynn Koh, Suk Yeah Polly Poon, Dominik Stanojevic, Hoang-Dai Tran, Kok Hao Edwin Lim, Shen Yon Toh, Philip Andrew Ewels, Huck-Hui Ng, N. Gopalakrishna Iyer, Alexandre Thiery, Wee Joo Chng, Leilei Chen, Ramanuj DasGupta, Mile Sikic, Yun-Shen Chan, Boon Ooi Patrick Tan, Yue Wan, Wai Leong Tam, Qiang Yu, Chiea Chuan Khor, Torsten Wüstefeld, Alexander Lezhava, Ploy N. Pratanwanich, Michael I. Love, Wee Siong Sho Goh, Sarah B. Ng, Alicia Oshlack, , N. Gopalakrishna Iyer, Qiang Yu, Jonathan Göke
24 Sep 2024 Current approaches to diagnosing and treating idiopathic granulomatous mastitis: A summary from in-depth clinician interviews Seeu Si Ong, Jean Xiang Ying Sim, Ching-Wan Chan, Peh Joo Ho, Zi Lin Lim, Mikael Hartman, Jingmei Li
21 Aug 2024 Genomic Insights into Idiopathic Granulomatous Mastitis through Whole-Exome Sequencing: A Case Report of Eight Patients Seeu Si Ong, Peh Joo Ho, Alexis Jiaying Khng, Benita Kiat Tee Tan, Qing Ting Tan, Ern Yu Tan, Su-Ming Tan, Thomas Choudary Putti, Swee Ho Lim, Ee Ling Serene Tang, Jingmei Li, Mikael Hartman