Genome Institute of Singapore

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Publication date Article title Author(s)
21 May 2026 Self‐Assembly of Stimuli‐Responsive Peptide Enhances Therapeutics by Specifically Disrupting Hepatocellular Carcinoma Lysosomes In Vivo Renwei Jing, Xiaorong Kong, Jin Zhang, Jiaxue Li, Xingjie He, Zhongqiu Yang, Yi Wang, Leijie Zhang, Qian Wang, Yiqi Seow, HaiFang Yin
9 Apr 2026 Improved tumor-only variant calling and mutation burden estimation with VarNet-T Kiran Krishnamachari, Huu An Bui Nguyen, Sinem Kadioglu, Jet Ong Tze, Anders Jacobsen Skanderup
19 Feb 2026 Setting higher standards for reports of microbial species in human cancers Steven L. Salzberg, Minghao Chia, Alfred Tay, Noel F.C.C. de Miranda, Vincent Smit, Jelle Wesseling, Rafael Irizarry, Barry Marshall, Eske Willerslev, Jacques Neefjes, Niranjan Nagarajan
24 Oct 2025 Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer Zhengwei Wu, Zhenxun Wang, Seow Qi Ng, Jessica Alice Lidster, Paul Schwerd-Kleine, Zi Jin Cheryl Phua, Kai Lay Esther Peh, Yin Ying Ho, Ju Yuan, S. Shathishwaran, Xun Hui Yeo, Ying Zhang, Yui Hei Jasper Chiu, Li Yieng Eunice Lau, Tony Kiat Hon Lim, Angela Takano, Eng Huat Tan, Anders Jacobsen Skanderup, Vinay Tergaonkar, Weiping Han, Ying Swan Ho, Daniel Shao Weng Tan, Wai Leong Tam
16 Oct 2025 Read-level DNA methylation deconvolution enhances circulating tumor DNA detection Ting Qi, Lakshmi Narayanan Lakshmanan, Yuwei Yang, Ying Zhou, Min Pan, Anders Jacobsen Skanderup, Qinyu Ge
26 Sep 2025 A conserved long-range RNA interaction in SARS-CoV-2 recruits ADAR1 to enhance virus proliferation Siwy Ling Yang, Louis DeFalco, Sainan Wang, Yi Hao Wong, Jian Han, Chee Keng Mok, Kiat Yee Tan, Su Ying Lim, Zhiya Zhao, Yu Zhang, Jovi Jian An Lim, Joy S. Xiang, Radoslaw Sobota, Lin-Fa Wang, Justin Jang Hann Chu, Andres Merits, Roland G. Huber, Yue Wan
11 Sep 2025 Emerging principles and models of human primordial germ cell development Navin B. Ramakrishna, João Pedro Alves-Lopes, Wolfram H. Gruhn
28 Aug 2025 Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human body Minghao Chia, Amanda Hui Qi Ng, Aarthi Ravikrishnan, Ahmad Nazri Mohamed Naim, Stephen Wearne, John Common, Niranjan Nagarajan
30 Jul 2025 Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning Mauricio Perez, Michiko Kimoto, Priscilla Rajakumar, Chayaporn Suphavilai, Rafael Peres da Silva, Hui Pen Tan, Nicholas Ting Xun Ong, Hannah Nicholas, Ichiro Hirao, Wei Leong Chew, Niranjan Nagarajan
10 Apr 2025 FBXO22 deficiency defines a pleiotropic syndrome of growth restriction and multi-system anomalies associated with a unique epigenetic signature Navin B. Ramakrishna, Umar Bin Mohamad Sahari, Yoshikazu Johmura, Nur Ain Ali, Malak Alghamdi, Peter Bauer, Suliman Khan, Natalia Ordoñez, Mariana Ferreira, Jorge Pinto Basto, Fowzan S. Alkuraya, Eissa Ali Faqeih, Mari Mori, Naif A.M. Almontashiri, Aisha Al Shamsi, Gehad ElGhazali, Hala Abu Subieh, Mode Al Ojaimi, Ayman W. El-Hattab, Said Ahmed Said Al-Kindi, Nadia Alhashmi, Fahad Alhabshan, Abdulaziz Al Saman, Hala Tfayli, Mariam Arabi, Simone Khalifeh, Alan Taylor, Majid Alfadhel, Ruchi Jain, Shruti Sinha, Shruti Shenbagam, Revathy Ramachandran, Umut Altunoglu, Anju Jacob, Nandu Thalange, Mireille El Bejjani, Arnaud Perrin, Jay W. Shin, Almundher Al-Maawali, Azza Al-Shidhani, Amna Al-Futaisi, Fatma Rabea, Ikram Chekroun, Mohamed A. Almarri, Tomohiko Ohta, Makoto Nakanishi, Alawi Alsheikh-Ali, Fahad R. Ali, Aida M. Bertoli-Avella, Bruno Reversade, Ahmad Abou Tayoun