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13 Sep 2025
BMRC
Institute of Molecular and Cell Biology
Comparative transcriptomics of lateral hypothalamic cell types reveals conserved growth hormone-tachykinin dynamics in feeding
Vindhya Chaganty,
Ruey-Kuang Cheng,
Kimberle Shen,
Na Zhang,
Gaynah Javier Doblado,
Sarah Ong,
Sandra Tan,
Valarie Yu Yan Tham,
Jung-Hwa Choi,
Marnie E. Halpern,
Wei Leong Chew,
Anand Kumar Andiappan,
Sarah Xinwei Luo,
Caroline Lei Wee
Molecular Metabolism
30 Jul 2025
BMRC
Genome Institute of Singapore
Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning
Mauricio Perez,
Michiko Kimoto,
Priscilla Rajakumar,
Chayaporn Suphavilai,
Rafael Peres da Silva,
Hui Pen Tan,
Nicholas Ting Xun Ong,
Hannah Nicholas,
Ichiro Hirao,
Wei Leong Chew,
Niranjan Nagarajan
Nature Communications
9 Apr 2021
BMRC
Institute of Molecular and Cell Biology
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity
Cheryl Q. E. Lee,
Baptiste Kerouanton,
Sonia Chothani,
Shan Zhang,
Ying Chen,
Chinmay Kumar Mantri,
Daniella Helena Hock,
Radiance Lim,
Rhea Nadkarni,
Vinh Thang Huynh,
Daryl Lim,
Wei Leong Chew,
Franklin L. Zhong,
David Arthur Stroud,
Sebastian Schafer,
Vinay Tergaonkar,
Ashley L. St John,
Owen J. L. Rackham,
Lena Ho
Nature Communications
2 Mar 2021
BMRC
Genome Institute of Singapore
Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins
Liwei Chen,
Jung Eun Park,
Peter Paa,
Priscilla D. Rajakumar,
Hong-Ting Prekop,
Yi Ting Chew,
Swathi N. Manivannan,
Wei Leong Chew
Nature Communications
22 Jul 2019
BMRC
Genome Institute of Singapore
Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy
Ana M. Moreno,
Nathan Palmer,
Fernando Alemán,
Genghao Chen,
Andrew Pla,
Ning Jiang,
Wei Leong Chew,
Mansun Law,
Prashant Mali
Nature Biomedical Engineering
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