Bioprocessing Technology Institute

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Publication date Article title Author(s)
25 Feb 2025 Multilevel─Intact, Subunits, and Peptides─Characterization of Antibody-Based Therapeutics by a Single-Column LC–MS Setup Kia-Ngee Low, Yee-Jiun Kok, Stephen Tate, Xuezhi Bi
31 Jan 2025 Enriching central memory T cells using novel bioreactor design for T cell manufacturing Sixun Chen, Akshaya V. Prabhu, Ahmad Amirul Bin Abdul Rahim, Kang-Zheng Lee, Dan Liu
30 Jan 2025 Muco‐Penetrating Lipid Nanoparticles Having a Liquid Core for Enhanced Intranasal mRNA Delivery Nipuni Maniyamgama, Ki Hyun Bae, Zi Wei Chang, Jialing Lee, Melgious J. Y. Ang, Yong Jie Tan, Lisa F. P. Ng, Laurent Renia, Kevin P. White, Yi Yan Yang
31 Dec 2024 Quality by Design in continuous bioprocessing: Investigating the impact of critical process parameters of multi-column chromatography during steady-state and transient phases Zi Ying Zheng, Ashley GuanBang Chen, Nuruljannah Dzulkiflie, Lyn Chiin Sim, Wen Qin Tang, Jiayu Leong, Wei Xuan Ler, Dawn Leong, Jake Chng, Norhaizat Bin Abdul Manan, Ian Walsh, Say Kong Ng, Maarten Pennings, Wei Zhang
23 Dec 2024 A Novel Crosslinking Approach for Biomanufacturing of a Collagen‐Based Skin Dermal Template Weng Wan Chan, Keya Rani Roy, Bach Quang Le, Hariharan Ezhilarasu, Xiaoqian Zhang, Ryan Yi Da Lim, Avinanda Banerjee, Mariya Kuriakose, Krystle Joy Ng, Priya Murugan, Chun Ting Goh, Weibiao Zhou, May Win Naing, Srikala Raghavan, Deepak Choudhury
29 Nov 2024 Cellulose functionalized magnetic beads for high throughput glycosylation analysis in biotherapeutic modalities Corrine Wan, Shi Jie Tay, Beiying Qiu, Sean Chia, Ian Walsh
20 Nov 2024 Device for automated aseptic sampling: Automated sampling solution for future cell and gene manufacturing Liu Dan, Wu Ying Ying, Akshaya V. Prabhu, Ahmad Amirul Bin Abdul Rahim, Zach Lee Jia Sheng
8 Nov 2024 Genome‐Scale Modeling of CHO Cells Unravel the Critical Role of Asparagine in Cell Culture Feed Media Kuin Tian Pang, Yi Fan Hong, Fumi Shozui, Shunpei Furomitsu, Matthew Myint, Ying Swan Ho, Yaron R. Silberberg, Ian Walsh, Meiyappan Lakshmanan
8 Nov 2024 Real‐Time Adaptive Inline Acidification Enhances Continuous pH Control for Viral Inactivation Jia Sheng Zach Lee, Tan Dai Nguyen, Zi Ying Zheng, Wei Zhang, Dan Liu
18 Oct 2024 Thermal and pH stress dictate distinct mechanisms of monoclonal antibody aggregation Kong Meng Hoi, Kuin Tian Pang, Corrine Wan, Zi Ying Zheng, Beiying Qiu, Yuansheng Yang, Zhang Wei, Ying Swan Ho, Ian Walsh, Sean Chia