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30 Apr 2026
SERC
Institute of Sustainability for Chemicals, Energy and Environment
Accelerating natural product discovery with linked MS-genomics and language/transformer-based models
Dillon Tay,
Winston Koh,
Shi Jun Ang,
Marvin Wong,
Yi Wee Lim,
Elena Heng,
Yu Hung Ng,
Naythan Yeo,
Krishnan Adaikkappan,
Fong Tian Wong,
Yee Hwee Lim
npj antimicrobials and resistance
3 Dec 2025
SERC
Institute of Sustainability for Chemicals, Energy and Environment
Enhancing Secondary Metabolite Production in Actinobacteria Through Over-Expression of a Medium-Sized SARP Regulator
Elena Heng,
Lee Ling Tan,
Yi Wee Lim,
Winston Koh,
Siew Bee Ng,
Yee Hwee Lim,
Dillon W. P. Tay,
Fong Tian Wong
International Journal of Molecular Sciences
21 Oct 2024
BMRC
Bioinformatics Institute
Structure-Guided Bacteria Specificity and Wide Activity Spectrum of Endotoxin-Responsive Peptide Nanonets
Nhan Dai Thien Tram,
Jan Kazimierz Marzinek,
Louis Perrin,
Devika Mukherjee,
Vanitha Selvarajan,
Peter John Bond,
Pui Lai Rachel Ee
Nano Letters
3 Jan 2024
BMRC
Bioinformatics Institute
High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against nontuberculous mycobacteria in vitro and in vivo
Priya Ragunathan,
Patcharaporn Sae-Lao,
Claire Hamela,
Matthéo Alcaraz,
Alexander Krah,
Wee Han Poh,
Carmen Jia Ern Pee,
Albert Yick Hou Lim,
Scott A. Rice,
Kevin Pethe,
Peter J. Bond,
Thomas Dick,
Laurent Kremer,
Roderick W. Bates,
Gerhard Gruber
Journal of Biological Chemistry
28 Apr 2020
BMRC
Singapore Institute for Clinical Sciences
Longitudinal assessment of antibiotic resistance gene profiles in gut microbiomes of infants at risk of eczema
Evelyn Xiu Ling Loo,
Amanda Zain,
Gaik Chin Yap,
Rikky W. Purbojati,
Daniela I. Drautz-Moses,
Yan Qing Koh,
Yap Seng Chong,
Koh Hian Tan,
Peter D. Gluckman,
Fabian Yap,
Johan Gunnar Eriksson,
Elizabeth Tham,
Lynette Pei-chi Shek,
Staffan Kjelleberg,
Stephan C. Schuster,
Ritu Banerjee,
Bee Wah Lee
BMC Infectious Diseases
19 Mar 2020
BMRC
Bioinformatics Institute
Identification and engineering of 32 membered antifungal macrolactone notonesomycins
Falicia Goh,
Mingzi M. Zhang,
Tian Ru Lim,
Kia Ngee Low,
Choy Eng Nge,
Elena Heng,
Wan Lin Yeo,
Fernanda L. Sirota,
Sharon Crasta,
Zann Tan,
Veronica Ng,
Chung Yan Leong,
Hubin Zhang,
Alexander Lezhava,
Swaine L. Chen,
Shawn S. Hoon,
Frank Eisenhaber,
Birgit Eisenhaber,
Yoganathan Kanagasundaram,
Fong T. Wong,
Siew Bee Ng
Microbial Cell Factories
8 Feb 2019
BMRC
Bioprocessing Technology Institute
HEXIM1 Peptide Exhibits Antimicrobial Activity Against Antibiotic Resistant Bacteria Through Guidance of Cell Penetrating Peptide
Pooi Leng Ho,
Han Kee Ong,
Jeanette Teo,
Dave Siak-Wei Ow,
Sheng-Hao Chao
Frontiers in Microbiology
18 May 2018
BMRC
Bioinformatics Institute
Antimicrobial activity profiles of Amphiphilic Xanthone derivatives are a function of their molecular Oligomerization
Jun-Jie Koh,
Shuimu Lin,
Yang Bai,
Wendy Wan Ling Sin,
Thet Tun Aung,
Jianguo Li,
Verma Chandra,
Konstantin Pervushin,
Roger W. Beuerman,
Shouping Liu
Biochimica et Biophysica Acta (BBA) - Biomembranes
15 Dec 2014
BMRC
Bioprocessing Technology Institute
Generation of novel monoclonal antibodies for the enrichment and characterization of human corneal endothelial cells (hCENC) necessary for the treatment of corneal endothelial blindness
Vanessa Ding,
Angela Chin,
Gary Peh,
Jodhbir S. Mehta,
Andre Choo
mAbs
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