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6 Jul 2026
Others
Experimental Drug Development Centre
ScrambleBench: a workflow for comparative assessment of structure-based de novo generative models
(Pending publish)
Veincent Yap,
Pan Xu,
Frankie S. Mak,
Klement Foo,
CongBao Kang,
Padmanabhan Anbazhagan,
Weijun Xu
Journal of Cheminformatics
26 Mar 2026
Others
Experimental Drug Development Centre
In Silico‐Enabled Discovery and Development of Potent and Selective CDK11 Inhibitors
(Pending publish)
Frankie S. Mak,
Fui Mee Ng,
Padmanabhan Anbazhagan,
Vikas Madan,
Qian Wen Tan,
Yiyang See,
Diane Lim,
Frances Karla Kusuma,
Hannah Toh,
Juliana Mohammad,
Haiyan Yang,
Sandra Sim,
Li Hong Tan,
Eileen Tay,
Ronald Toh Kuan Hai,
Perlyn Zekui Kwek,
Mei Yee Wong,
Deepika Raman,
Qi An Ang,
Vithya Manoharan,
Susmitha Vuddagiri,
Monique Danielle Dawson,
Alison Tan,
Joma Kanikadu Joy,
Bong Hwa Gan,
Choon Bing Low,
Haoying Xu,
Siew Pheng Lim,
Hannes Hentze,
Joseph Cherian,
Chong Teik Tan,
Jackie Ang,
Kantharaj Ethirajulu,
Klement Foo,
Inderjeet Singh,
Weijun Xu
ChemMedChem
12 Feb 2026
Others
Experimental Drug Development Centre
Macrocycles: On the Rise for Bridging Small Molecules and Biologics
(Pending publish)
Klement Foo,
Kantharaj Ethirajulu,
Weijun Xu
Journal of Medicinal Chemistry
15 May 2025
Others
Experimental Drug Development Centre
Towards global reaction feasibility and robustness prediction with high throughput data and bayesian deep learning
Haowen Zhong,
Yilan Liu,
Haibin Sun,
Yuru Liu,
Rentao Zhang,
Baochen Li,
Yi Yang,
Yuqing Huang,
Fei Yang,
Frankie S. Mak,
Klement Foo,
Sen Lin,
Tianshu Yu,
Peng Wang,
Xiaoxue Wang
Nature Communications
12 May 2025
Others
Experimental Drug Development Centre
An Evolving Landscape of Small Molecules Targeting SARS-CoV-2: What Are We Awaiting Beyond 3CLpro Inhibitors?
(Pending publish)
CongBao Kang,
Klement Foo,
Kantharaj Ethirajulu,
Weijun Xu
Journal of Medicinal Chemistry
25 Apr 2025
Others
Experimental Drug Development Centre
Structure-based discovery of novel non-covalent small molecule inhibitors of USP30
Padmanabhan Anbazhagan,
Jothi Anantharajan,
Justina Fulwood,
Choon Heng Low,
Nithya Baburajendran,
Klement Foo,
Weijun Xu
Journal of Computer-Aided Molecular Design
3 Sep 2024
Others
Experimental Drug Development Centre
Regio-MPNN: predicting regioselectivity for general metal-catalyzed cross-coupling reactions using a chemical knowledge informed message passing neural network
Baochen Li,
Yuru Liu,
Haibin Sun,
Rentao Zhang,
Yongli Xie,
Klement Foo,
Frankie S. Mak,
Ruimao Zhang,
Tianshu Yu,
Sen Lin,
Peng Wang,
Xiaoxue Wang
Digital Discovery
23 May 2019
Others
Experimental Drug Development Centre
Discovery of Irreversible Inhibitors Targeting Histone Methyltrans-ferase, SMYD3
Chuhui Huang,
Si Si Liew,
Grace R Lin,
Anders Poulsen,
Melgious J. Y. Ang,
Brian C. S. Chia,
Sin Yin Chew,
Zekui Perlyn Kwek,
John L. K. Wee,
Esther H. Ong,
Priya Retna,
Nithya Baburajendran,
Rong Li,
Weixuan Yu,
Xiaoying Koh-Stenta,
Anna Ngo,
Sravanthy Manesh,
Justina Fulwood,
Zhiyuan Ke,
Hwa Hwa Chung,
Sugunavathi Sepramaniam,
Xin Hui Chew,
Nurul Dinie,
Yun Shan Chew,
May Ann Lee,
Choon Bing Low,
Vishal Pendharkar,
Vithya Manoharan,
Susmitha Vuddagiri,
Kanda Sangthongpitag,
Joma Joy,
Alex Matter,
Jeffrey Hill,
Thomas Keller,
Klement Foo
ACS Medicinal Chemistry Letters
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