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23 May 2019
Others
Experimental Drug Development Centre
Discovery of Irreversible Inhibitors Targeting Histone Methyltrans-ferase, SMYD3
Chuhui Huang,
Si Si Liew,
Grace R Lin,
Anders Poulsen,
Melgious J. Y. Ang,
Brian C. S. Chia,
Sin Yin Chew,
Zekui Perlyn Kwek,
John L. K. Wee,
Esther H. Ong,
Priya Retna,
Nithya Baburajendran,
Rong Li,
Weixuan Yu,
Xiaoying Koh-Stenta,
Anna Ngo,
Sravanthy Manesh,
Justina Fulwood,
Zhiyuan Ke,
Hwa Hwa Chung,
Sugunavathi Sepramaniam,
Xin Hui Chew,
Nurul Dinie,
Yun Shan Chew,
May Ann Lee,
Choon Bing Low,
Vishal Pendharkar,
Vithya Manoharan,
Susmitha Vuddagiri,
Kanda Sangthongpitag,
Joma Joy,
Alex Matter,
Jeffrey Hill,
Thomas Keller,
Klement Foo
ACS Medicinal Chemistry Letters
11 Aug 2018
Others
Experimental Drug Development Centre
Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria
Soo Yei Ho,
Weiling Wang,
Fui Mee Ng,
Yun Xuan Wong,
Zhi Ying Poh,
Wai Sum Eldwin Tan,
Shi Hua Ang,
Si Si Liew,
Yin Sze Joyner Wong,
Yvonne Tan,
Anders Poulsen,
Vishal Pendharkar,
Kanda Sangthongpitag,
John Manchester,
Gregory Basarab,
Jeffrey Hill,
Thomas H. Keller,
Joseph Cherian
European Journal of Medicinal Chemistry
5 Jul 2018
BMRC
Bioinformatics Institute
Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide
Bee Hui Liu,
Chacko Jobichen,
C. S. Brian Chia,
Tim Hon Man Chan,
Jing Ping Tang,
Theodora X. Y. Chung,
Jia Li,
Anders Poulsen,
Alvin W. Hung,
Xiaoying Koh-Stenta,
Yaw Sing Tan,
Chandra S. Verma,
Hong Kee Tan,
Chan-shuo Wu,
Feng Li,
Jeffrey Hill,
Joma Joy,
Henry Yang,
Li Chai,
J. Sivaraman,
Daniel G. Tenen
Proceedings of the National Academy of Sciences
5 Jul 2018
Others
Experimental Drug Development Centre
Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide
Bee Hui Liu,
Chacko Jobichen,
Cheng San Brian Chia,
Tim Hon Man Chan,
Jing Ping Tang,
Theodora Chung,
Jia Li,
Anders Poulsen,
Alvin W. Hung,
Xiaoying Koh-Stenta,
Yaw Sing Tan,
Chandra S. Verma,
Hong Kee Tan,
Chan-shuo Wu,
Feng Li,
Jeffrey Hill,
Joma Joy,
Henry Yang,
Li Chai,
J. Sivaraman,
Daniel G. Tenen
PNAS
23 May 2018
Others
Experimental Drug Development Centre
Structural and ligand binding analysis of the YAP-binding domain of transcription factor TEAD4
Yan Li,
Shuang Liu,
Elizabeth Yihui Ng,
Rong Li,
Anders Poulsen,
Jeffrey Hill,
CongBao Kang,
Ajaybabu Pobbati,
Alvin Wei Hung,
Wanjin Hong,
Thomas Keller
Biochemical Journal
24 Apr 2018
Others
Experimental Drug Development Centre
Fragment-based drug discovery of potent Protein Kinase C-iota inhibitors
Jacek Kwiatkowski,
Boping Liu,
Doris Hui Ying Tee,
Guoying Chen,
Nur Huda Binte Ahmad,
Yun Xuan Wong,
Zhi Ying Poh,
Shi Hua Ang,
Eldwin Sum Wai Tan,
Esther Ong,
Nurul Dinie,
Anders Poulsen,
Vishal Pendharkar,
Kanda Sangthongpitag,
May Ann Lee,
Sugunavathi D/O Sepramaniam,
Soo Yei Ho,
Joseph Cherian,
Jeffrey Hill,
Thomas Hugo Keller,
Alvin Wei Hung
Journal of Medicinal Chemistry
23 Apr 2018
BMRC
Bioinformatics Institute
Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia
Haiyan Yang,
Lohitha Rao Chennamaneni,
Melvyn Wai Tuck Ho,
Shi Hua Ang,
Eldwin Sum Wai Tan,
Duraiswamy Athisayamani Jeyaraj,
Yoon Sheng Yeap,
Boping Liu,
Esther Hq Ong,
Joma Kanikadu Joy,
John Liang Kuan Wee,
Perlyn Kwek,
Priya Retna,
Nurul Dinie,
Thuy Thi Hanh Nguyen,
Shi Jing Tai,
Vithya Manoharan,
Vishal Pendharkar,
Choon Bing Low,
Yun Shan Chew,
Susmitha Vuddagiri,
Kanda Sangthongpitag,
Meng Ling Choong,
May Ann Lee,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Anders Poulsen,
Sharon Lim,
Charles Chuah,
Tiong Sin Ong,
Jeffrey Hill,
Alex Matter,
Kassoum Nacro
Journal of Medicinal Chemistry
7 Mar 2017
Others
Experimental Drug Development Centre
Discovery and characterisation of the automethylation properties of PRDM9
Xiaoying Koh-Stenta,
Anders Poulsen,
Rong Li,
John Liang Kuan Wee,
Perlyn Zekui Kwek,
Sin Yin Chew,
Jianhe Peng,
Liling Wu,
Ernesto Guccione,
Joma Joy,
Jeffrey Hill
Biochemical Journal
18 Oct 2016
Others
Experimental Drug Development Centre
A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms.
Zhufang Ann Koay,
Christian Pecquet,
Carmen Diaconu,
Yasmine Ould-Amer,
CongBao Kang,
Anders Poulsen,
May Ann Lee,
David Jenkins,
Andrew Shiau,
Stefan Constantinescu,
Anna Ngo,
Meng Ling Choong
Combinatorial Chemistry & High Throughput Screening
31 May 2016
Others
Experimental Drug Development Centre
Miniature bovine pancreatic trypsin inhibitors (m-BPTIs) of the West Nile virus NS2B-NS3 protease
Anders Poulsen,
John Liang Kuan Wee,
Fui Mee Ng,
Joma Joy,
Jeffrey Hill,
J. Y. Melgious Ang,
C. S. Brian Chia,
Huichang Annie Lim
Journal of Enzyme Inhibition and Medicinal Chemistry
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