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19 Jul 2022
Others
Experimental Drug Development Centre
A Warhead Substitution Study on the Coronavirus Main Protease Inhibitor Nirmatrelvir
Subramanyam Vankadara,
Monique Danielle Dawson,
Jia Yi Fong,
Qin Yao Oh,
Qi An Ang,
Boping Liu,
Hong Yun Chang,
Judice Koh,
Xiaoying Koh,
Qian Wen Tan,
Joma Joy,
Cheng San Brian Chia
ACS Medicinal Chemistry Letters
14 Jul 2021
Others
Experimental Drug Development Centre
A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors
Subramanyam Vankadara,
Yun Xuan Wong,
Boping Liu,
Yi Yang See,
Li Hong Tan,
Qian Wen Tan,
Gang Wang,
Ratna Karuna,
Xue Guo,
Shu Ting Tan,
Jia Yi Fong,
Joma Joy,
C.S. Brian Chia
Bioorganic & Medicinal Chemistry Letters
23 May 2019
Others
Experimental Drug Development Centre
Discovery of Irreversible Inhibitors Targeting Histone Methyltrans-ferase, SMYD3
Chuhui Huang,
Si Si Liew,
Grace R Lin,
Anders Poulsen,
Melgious J. Y. Ang,
Brian C. S. Chia,
Sin Yin Chew,
Zekui Perlyn Kwek,
John L. K. Wee,
Esther H. Ong,
Priya Retna,
Nithya Baburajendran,
Rong Li,
Weixuan Yu,
Xiaoying Koh-Stenta,
Anna Ngo,
Sravanthy Manesh,
Justina Fulwood,
Zhiyuan Ke,
Hwa Hwa Chung,
Sugunavathi Sepramaniam,
Xin Hui Chew,
Nurul Dinie,
Yun Shan Chew,
May Ann Lee,
Choon Bing Low,
Vishal Pendharkar,
Vithya Manoharan,
Susmitha Vuddagiri,
Kanda Sangthongpitag,
Joma Joy,
Alex Matter,
Jeffrey Hill,
Thomas Keller,
Klement Foo
ACS Medicinal Chemistry Letters
5 Jul 2018
BMRC
Bioinformatics Institute
Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide
Bee Hui Liu,
Chacko Jobichen,
C. S. Brian Chia,
Tim Hon Man Chan,
Jing Ping Tang,
Theodora X. Y. Chung,
Jia Li,
Anders Poulsen,
Alvin W. Hung,
Xiaoying Koh-Stenta,
Yaw Sing Tan,
Chandra S. Verma,
Hong Kee Tan,
Chan-shuo Wu,
Feng Li,
Jeffrey Hill,
Joma Joy,
Henry Yang,
Li Chai,
J. Sivaraman,
Daniel G. Tenen
Proceedings of the National Academy of Sciences
5 Jul 2018
Others
Experimental Drug Development Centre
Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide
Bee Hui Liu,
Chacko Jobichen,
Cheng San Brian Chia,
Tim Hon Man Chan,
Jing Ping Tang,
Theodora Chung,
Jia Li,
Anders Poulsen,
Alvin W. Hung,
Xiaoying Koh-Stenta,
Yaw Sing Tan,
Chandra S. Verma,
Hong Kee Tan,
Chan-shuo Wu,
Feng Li,
Jeffrey Hill,
Joma Joy,
Henry Yang,
Li Chai,
J. Sivaraman,
Daniel G. Tenen
PNAS
14 Aug 2017
Others
Experimental Drug Development Centre
Backbone resonance assignments for the SET domain of human methyltransferase NSD3 in complex with its cofactor
Thomas Hugo Keller,
CongBao Kang,
Yan Li,
Hui Qi Ng,
Anna Ngo,
Joma Joy,
Jeffrey Hill,
Pearlyn Kwek,
Alvin Hung
Biomolecular NMR Assignments
7 Mar 2017
Others
Experimental Drug Development Centre
Discovery and characterisation of the automethylation properties of PRDM9
Xiaoying Koh-Stenta,
Anders Poulsen,
Rong Li,
John Liang Kuan Wee,
Perlyn Zekui Kwek,
Sin Yin Chew,
Jianhe Peng,
Liling Wu,
Ernesto Guccione,
Joma Joy,
Jeffrey Hill
Biochemical Journal
31 May 2016
Others
Experimental Drug Development Centre
Miniature bovine pancreatic trypsin inhibitors (m-BPTIs) of the West Nile virus NS2B-NS3 protease
Anders Poulsen,
John Liang Kuan Wee,
Fui Mee Ng,
Joma Joy,
Jeffrey Hill,
J. Y. Melgious Ang,
C. S. Brian Chia,
Huichang Annie Lim
Journal of Enzyme Inhibition and Medicinal Chemistry
15 Jul 2014
Others
Experimental Drug Development Centre
Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques
Xiaoying Koh-Stenta,
Joma Joy,
Anders Poulsen,
Yvonne Tan,
Anna Ngo,
Jianhe Peng,
Wei Guamg Seetoh,
Jing Cao,
John Liang Kuan Wee,
Perlyn Zekui Kwek,
Alvin Hung,
Umayal Lakshmanan,
Horst Flowtow,
Jeffrey Hill
Biochemical Journal
9 Dec 2013
Others
Experimental Drug Development Centre
A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides
Melgious Jin Yan Ang,
Zhitao Li,
Huichang Annie Lim,
Fui Mee Ng,
Siew Wen Then,
John Liang Kuan Wee,
Joma Joy,
Jeffrey Hill,
C.S. Brian Chia
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