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Publication date Communities Collections Article title Author(s) Journal/Conference
23 May 2019 BMRC Experimental Drug Development Centre Discovery of Irreversible Inhibitors Targeting Histone Methyltrans-ferase, SMYD3 Chuhui Huang, Si Si Liew, Grace R Lin, Anders Poulsen, Melgious J. Y. Ang, Brian C. S. Chia, Sin Yin Chew, Zekui Perlyn Kwek, John L. K. Wee, Esther H. Ong, Priya Retna, Nithya Baburajendran, Rong Li, Weixuan Yu, Xiaoying Koh-Stenta, Anna Ngo, Sravanthy Manesh, Justina Fulwood, Zhiyuan Ke, Hwa Hwa Chung, Sugunavathi Sepramaniam, Xin Hui Chew, Nurul Dinie, Yun Shan Chew, May Ann Lee, Choon Bing Low, Vishal Pendharkar, Vithya Manoharan, Susmitha Vuddagiri, Kanda Sangthongpitag, Joma Joy, Alex Matter, Jeffrey Hill, Thomas Keller, Klement Foo ACS Medicinal Chemistry Letters
23 May 2018 BMRC Experimental Drug Development Centre Structural and ligand binding analysis of the YAP-binding domain of transcription factor TEAD4 Yan Li, Shuang Liu, Elizabeth Yihui Ng, Rong Li, Anders Poulsen, Jeffrey Hill, CongBao Kang, Ajaybabu Pobbati, Alvin Wei Hung, Wanjin Hong, Thomas Keller Biochemical Journal
6 Feb 2018 BMRC Experimental Drug Development Centre Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small molecule inhibitor Kassoum Nacro, Yan Li, Zhenzhen Zhang, Ying Ru Loh, Rong Li, Hai Yan Yang, Anna Jansson, Jeffrey Hill, Thomas Keller, Dahai Luo, CongBao Kang Structure
5 Aug 2017 BMRC Experimental Drug Development Centre Zika Virus Protease: An Antiviral Drug Target CongBao Kang, Thomas Keller, Dahai Luo Trends in Microbiology
4 Nov 2015 BMRC Experimental Drug Development Centre Biophysical studies of type II topoisomerases from Pseudomonas aeruginosa and Streptococcus pneumoniae substantiate their binding modes to a bis-pyridylurea inhibitor. Boping Liu, CongBao Kang, Yan Li, Joseph Cherian, Hui Qi Ng, Michelle Yueqi Lee, Nur Huda Ahmad, Zhi Ying Poh, Yun Xuan Wong, Qiwei Huang, Ying Lei Wong, Alvin Hung, Jeffrey Hill, Thomas Keller Biophysical Journal
23 Oct 2015 BMRC Experimental Drug Development Centre The use of porcupine inhibitors to target Wnt-driven cancers Soo Yei Ho, Thomas Keller Bioorganic & Medicinal Chemistry Letters
10 Aug 2015 BMRC Experimental Drug Development Centre Wnt addiction of genetically defined cancers reversed by PORCN inhibition Babita Madan, Zhiyuan Ke, Nathan Harmston, Soo Yei Ho, Frois Ashley Oliver, Jenefer Alam, Duraiswamy Jeyaraj, Vishal Pendharkar, Kakaly Ghosh, Isaac H Virshup, Vithya Manoharan, Esther Hq Ong, Kanda Sangthongpitag, Jeffrey Hill, Enrico Petretto, Thomas Keller, May Ann Lee, Alex Matter, David M Virshup Oncogene
24 Jun 2015 BMRC Experimental Drug Development Centre Application of Fragment-Based Drug Discovery against DNA Gyrase B Cheng San Brian Chia, Qiu Ying Lau, Jeffrey Hill, Alvin Hung, Thomas Keller, Siew Wen Then, Nur Huda Ahmad, Ying Lei Wong, Hui Qi Ng, Guo-Ying Chen, Fui Mee Ng, Yih Wan Tan, Anders Poulsen, Wei Guang Seetoh, Grace Lin, CongBao Kang ChemPlusChem
29 May 2015 BMRC Experimental Drug Development Centre A Pharmacophore Model for Wnt/Porcupine Inhibitors and its Use for Drug Design Grace Ruiting Lin, Vivien Wei Wen Cheong, Zhiyuan Ke, May Ann Lee, Thomas Keller, Anders Poulsen, Soo Yei Ho, Weiling Wang, Jenefer Alam, Duraiswamy Jeyaraj, Shi Hua Ang, Eldwin Sum Wai Tan Journal of Chemical Information and Modeling