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Publication date Communities Collections Article title Author(s) Journal/Conference
15 Apr 2024 Others Experimental Drug Development Centre Cytotoxic activity and cell specificity of a novel LHRH peptide drug conjugate, D-Cys6-LHRH vedotin, against ovarian cancer cell lines Subramanyam Vankadara, Zhiyuan Ke, Sifang Wang, Sin Yun Foo, Jayantha Gunaratne, May Ann Lee, Xiaoying Koh, C. S. Brian Chia Chemical Biology & Drug Design
23 May 2019 Others Experimental Drug Development Centre Discovery of Irreversible Inhibitors Targeting Histone Methyltrans-ferase, SMYD3 Chuhui Huang, Si Si Liew, Grace R Lin, Anders Poulsen, Melgious J. Y. Ang, Brian C. S. Chia, Sin Yin Chew, Zekui Perlyn Kwek, John L. K. Wee, Esther H. Ong, Priya Retna, Nithya Baburajendran, Rong Li, Weixuan Yu, Xiaoying Koh-Stenta, Anna Ngo, Sravanthy Manesh, Justina Fulwood, Zhiyuan Ke, Hwa Hwa Chung, Sugunavathi Sepramaniam, Xin Hui Chew, Nurul Dinie, Yun Shan Chew, May Ann Lee, Choon Bing Low, Vishal Pendharkar, Vithya Manoharan, Susmitha Vuddagiri, Kanda Sangthongpitag, Joma Joy, Alex Matter, Jeffrey Hill, Thomas Keller, Klement Foo ACS Medicinal Chemistry Letters
24 Apr 2018 Others Experimental Drug Development Centre Fragment-based drug discovery of potent Protein Kinase C-iota inhibitors Jacek Kwiatkowski, Boping Liu, Doris Hui Ying Tee, Guoying Chen, Nur Huda Binte Ahmad, Yun Xuan Wong, Zhi Ying Poh, Shi Hua Ang, Eldwin Sum Wai Tan, Esther Ong, Nurul Dinie, Anders Poulsen, Vishal Pendharkar, Kanda Sangthongpitag, May Ann Lee, Sugunavathi D/O Sepramaniam, Soo Yei Ho, Joseph Cherian, Jeffrey Hill, Thomas Hugo Keller, Alvin Wei Hung Journal of Medicinal Chemistry
23 Apr 2018 BMRC Bioinformatics Institute Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia Haiyan Yang, Lohitha Rao Chennamaneni, Melvyn Wai Tuck Ho, Shi Hua Ang, Eldwin Sum Wai Tan, Duraiswamy Athisayamani Jeyaraj, Yoon Sheng Yeap, Boping Liu, Esther Hq Ong, Joma Kanikadu Joy, John Liang Kuan Wee, Perlyn Kwek, Priya Retna, Nurul Dinie, Thuy Thi Hanh Nguyen, Shi Jing Tai, Vithya Manoharan, Vishal Pendharkar, Choon Bing Low, Yun Shan Chew, Susmitha Vuddagiri, Kanda Sangthongpitag, Meng Ling Choong, May Ann Lee, Srinivasaraghavan Kannan, Chandra S. Verma, Anders Poulsen, Sharon Lim, Charles Chuah, Tiong Sin Ong, Jeffrey Hill, Alex Matter, Kassoum Nacro Journal of Medicinal Chemistry
18 Oct 2016 Others Experimental Drug Development Centre A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms. Zhufang Ann Koay, Christian Pecquet, Carmen Diaconu, Yasmine Ould-Amer, CongBao Kang, Anders Poulsen, May Ann Lee, David Jenkins, Andrew Shiau, Stefan Constantinescu, Anna Ngo, Meng Ling Choong Combinatorial Chemistry & High Throughput Screening
24 Mar 2016 Others Experimental Drug Development Centre Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 & 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells Kassoum Nacro, Zhi Ying Poh, Samantha Guo, Joseph Cherian, Duraiswamy Jeyaraj, Yun Xuan Wong, Melvyn Ho, Hai Yan Yang, Joma Kanikadu Joy, Zekui Perlyn Kwek, Boping Liu, John Laing Kuan Wee Wee, Esther Hq Ong, Meng Ling Choong, Anders Poulsen, May Ann Lee, Vishal Pendharkar, Vithya Manoharan, Yun Shan Chew, Kanda Sangthongpitag, Sharon Lim, S. Tiong Ong, Jeffrey Hill, Thomas H. Keller Journal of Medicinal Chemistry
10 Aug 2015 Others Experimental Drug Development Centre Wnt addiction of genetically defined cancers reversed by PORCN inhibition Babita Madan, Zhiyuan Ke, Nathan Harmston, Soo Yei Ho, Frois Ashley Oliver, Jenefer Alam, Duraiswamy Jeyaraj, Vishal Pendharkar, Kakaly Ghosh, Isaac H Virshup, Vithya Manoharan, Esther Hq Ong, Kanda Sangthongpitag, Jeffrey Hill, Enrico Petretto, Thomas Keller, May Ann Lee, Alex Matter, David M Virshup Oncogene
25 Jun 2015 Others Experimental Drug Development Centre Discovery and Optimization of a Porcupine Inhibitor Athisayamani Jeyaraj Duraiswamy, May Ann Lee, Babita Madan, Shi Hua Ang, Eldwin Sum Wai Tan, Wei Wen Vivien Cheong, Zhiyuan Ke, Vishal Pendharkar, Li Jun Ding, Yun Shan Chew, Vithya Manoharan, Kanda Sangthongpitag, Jenefer Alam, Anders Poulsen, Soo Yei Ho, David Virshup, Thomas Hugo Keller Journal of Medicinal Chemistry
29 May 2015 Others Experimental Drug Development Centre A Pharmacophore Model for Wnt/Porcupine Inhibitors and its Use for Drug Design Grace Ruiting Lin, Vivien Wei Wen Cheong, Zhiyuan Ke, May Ann Lee, Thomas Keller, Anders Poulsen, Soo Yei Ho, Weiling Wang, Jenefer Alam, Duraiswamy Jeyaraj, Shi Hua Ang, Eldwin Sum Wai Tan Journal of Chemical Information and Modeling
30 Jun 2014 Others Experimental Drug Development Centre Establishment and Characterization of a Singaporean Chinese Lung Adenocarcinoma Cell Line with Four Copies of the Epidermal Growth Factor Receptor Gene Meng Ling Choong, Jacklyn Yong, Yu Wang, May Ann Lee BioResearch Open Access