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23 May 2019
Others
Experimental Drug Development Centre
Discovery of Irreversible Inhibitors Targeting Histone Methyltrans-ferase, SMYD3
Chuhui Huang,
Si Si Liew,
Grace R Lin,
Anders Poulsen,
Melgious J. Y. Ang,
Brian C. S. Chia,
Sin Yin Chew,
Zekui Perlyn Kwek,
John L. K. Wee,
Esther H. Ong,
Priya Retna,
Nithya Baburajendran,
Rong Li,
Weixuan Yu,
Xiaoying Koh-Stenta,
Anna Ngo,
Sravanthy Manesh,
Justina Fulwood,
Zhiyuan Ke,
Hwa Hwa Chung,
Sugunavathi Sepramaniam,
Xin Hui Chew,
Nurul Dinie,
Yun Shan Chew,
May Ann Lee,
Choon Bing Low,
Vishal Pendharkar,
Vithya Manoharan,
Susmitha Vuddagiri,
Kanda Sangthongpitag,
Joma Joy,
Alex Matter,
Jeffrey Hill,
Thomas Keller,
Klement Foo
ACS Medicinal Chemistry Letters
11 Aug 2018
Others
Experimental Drug Development Centre
Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria
Soo Yei Ho,
Weiling Wang,
Fui Mee Ng,
Yun Xuan Wong,
Zhi Ying Poh,
Wai Sum Eldwin Tan,
Shi Hua Ang,
Si Si Liew,
Yin Sze Joyner Wong,
Yvonne Tan,
Anders Poulsen,
Vishal Pendharkar,
Kanda Sangthongpitag,
John Manchester,
Gregory Basarab,
Jeffrey Hill,
Thomas H. Keller,
Joseph Cherian
European Journal of Medicinal Chemistry
24 Apr 2018
Others
Experimental Drug Development Centre
Fragment-based drug discovery of potent Protein Kinase C-iota inhibitors
Jacek Kwiatkowski,
Boping Liu,
Doris Hui Ying Tee,
Guoying Chen,
Nur Huda Binte Ahmad,
Yun Xuan Wong,
Zhi Ying Poh,
Shi Hua Ang,
Eldwin Sum Wai Tan,
Esther Ong,
Nurul Dinie,
Anders Poulsen,
Vishal Pendharkar,
Kanda Sangthongpitag,
May Ann Lee,
Sugunavathi D/O Sepramaniam,
Soo Yei Ho,
Joseph Cherian,
Jeffrey Hill,
Thomas Hugo Keller,
Alvin Wei Hung
Journal of Medicinal Chemistry
23 Apr 2018
BMRC
Bioinformatics Institute
Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia
Haiyan Yang,
Lohitha Rao Chennamaneni,
Melvyn Wai Tuck Ho,
Shi Hua Ang,
Eldwin Sum Wai Tan,
Duraiswamy Athisayamani Jeyaraj,
Yoon Sheng Yeap,
Boping Liu,
Esther Hq Ong,
Joma Kanikadu Joy,
John Liang Kuan Wee,
Perlyn Kwek,
Priya Retna,
Nurul Dinie,
Thuy Thi Hanh Nguyen,
Shi Jing Tai,
Vithya Manoharan,
Vishal Pendharkar,
Choon Bing Low,
Yun Shan Chew,
Susmitha Vuddagiri,
Kanda Sangthongpitag,
Meng Ling Choong,
May Ann Lee,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Anders Poulsen,
Sharon Lim,
Charles Chuah,
Tiong Sin Ong,
Jeffrey Hill,
Alex Matter,
Kassoum Nacro
Journal of Medicinal Chemistry
24 Apr 2017
SERC
Institute of Chemical and Engineering Sciences
Toward resolving the resveratrol conundrum : synthesis and in vivo pharmacokinetic evaluation of BCP-resveratrol
Yi Ling Goh,
Yan Ting Cui,
Vishal Pendharkar,
Vikrant A. Adsool
ACS Medicinal Chemistry Letters
24 Mar 2016
Others
Experimental Drug Development Centre
Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 & 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells
Kassoum Nacro,
Zhi Ying Poh,
Samantha Guo,
Joseph Cherian,
Duraiswamy Jeyaraj,
Yun Xuan Wong,
Melvyn Ho,
Hai Yan Yang,
Joma Kanikadu Joy,
Zekui Perlyn Kwek,
Boping Liu,
John Laing Kuan Wee Wee,
Esther Hq Ong,
Meng Ling Choong,
Anders Poulsen,
May Ann Lee,
Vishal Pendharkar,
Vithya Manoharan,
Yun Shan Chew,
Kanda Sangthongpitag,
Sharon Lim,
S. Tiong Ong,
Jeffrey Hill,
Thomas H. Keller
Journal of Medicinal Chemistry
10 Aug 2015
Others
Experimental Drug Development Centre
Wnt addiction of genetically defined cancers reversed by PORCN inhibition
Babita Madan,
Zhiyuan Ke,
Nathan Harmston,
Soo Yei Ho,
Frois Ashley Oliver,
Jenefer Alam,
Duraiswamy Jeyaraj,
Vishal Pendharkar,
Kakaly Ghosh,
Isaac H Virshup,
Vithya Manoharan,
Esther Hq Ong,
Kanda Sangthongpitag,
Jeffrey Hill,
Enrico Petretto,
Thomas Keller,
May Ann Lee,
Alex Matter,
David M Virshup
Oncogene
25 Jun 2015
Others
Experimental Drug Development Centre
Discovery and Optimization of a Porcupine Inhibitor
Athisayamani Jeyaraj Duraiswamy,
May Ann Lee,
Babita Madan,
Shi Hua Ang,
Eldwin Sum Wai Tan,
Wei Wen Vivien Cheong,
Zhiyuan Ke,
Vishal Pendharkar,
Li Jun Ding,
Yun Shan Chew,
Vithya Manoharan,
Kanda Sangthongpitag,
Jenefer Alam,
Anders Poulsen,
Soo Yei Ho,
David Virshup,
Thomas Hugo Keller
Journal of Medicinal Chemistry
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