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Publication date Communities Collections Article title Author(s) Journal/Conference
15 Apr 2024 BMRC Experimental Drug Development Centre Cytotoxic activity and cell specificity of a novel LHRH peptide drug conjugate, D-Cys6-LHRH vedotin, against ovarian cancer cell lines Subramanyam Vankadara, Zhiyuan Ke, Sifang Wang, Sin Yun Foo, Jayantha Gunaratne, May Ann Lee, Xiaoying Koh, C. S. Brian Chia Chemical Biology & Drug Design
15 Feb 2024 BMRC Experimental Drug Development Centre Identification of small‐molecule binding sites of a ubiquitin‐conjugating enzyme‐UBE2T through fragment‐based screening Yong Yao Loh, Jothi Anantharajan, Qiwei Huang, Weijun Xu, Justina Fulwood, Hui Qi Ng, Elizabeth Yihui Ng, Chong Yu Gea, Meng Ling Choong, Qian Wen Tan, Xiaoying Koh, Wan Hsin Lim, Kassoum Nacro, Joseph Cherian, Nithya Baburajendran, Zhiyuan Ke, CongBao Kang Protein Science
11 Nov 2023 BMRC Experimental Drug Development Centre Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer Jothi Anantharajan, Qian Wen Tan, Justina Fulwood, Wang Sifang, Qiwei Huang, Hui Qi Ng, Xiaoying Koh, Weijun Xu, Joseph Cherian, Nithya Baburajendran, CongBao Kang, Zhiyuan Ke Biochemical and Biophysical Research Communications
29 Sep 2023 BMRC Experimental Drug Development Centre Backbone 1H, 15N and 13C resonance assignments for an E2 ubiquitin conjugating enzyme-UBE2T Qiwei Huang, Hui Qi Ng, Yong Yao Loh, Zhiyuan Ke, Wan Hsin Lim, CongBao Kang Biomolecular NMR Assignments
23 May 2019 BMRC Experimental Drug Development Centre Discovery of Irreversible Inhibitors Targeting Histone Methyltrans-ferase, SMYD3 Chuhui Huang, Si Si Liew, Grace R Lin, Anders Poulsen, Melgious J. Y. Ang, Brian C. S. Chia, Sin Yin Chew, Zekui Perlyn Kwek, John L. K. Wee, Esther H. Ong, Priya Retna, Nithya Baburajendran, Rong Li, Weixuan Yu, Xiaoying Koh-Stenta, Anna Ngo, Sravanthy Manesh, Justina Fulwood, Zhiyuan Ke, Hwa Hwa Chung, Sugunavathi Sepramaniam, Xin Hui Chew, Nurul Dinie, Yun Shan Chew, May Ann Lee, Choon Bing Low, Vishal Pendharkar, Vithya Manoharan, Susmitha Vuddagiri, Kanda Sangthongpitag, Joma Joy, Alex Matter, Jeffrey Hill, Thomas Keller, Klement Foo ACS Medicinal Chemistry Letters
10 Aug 2015 BMRC Experimental Drug Development Centre Wnt addiction of genetically defined cancers reversed by PORCN inhibition Babita Madan, Zhiyuan Ke, Nathan Harmston, Soo Yei Ho, Frois Ashley Oliver, Jenefer Alam, Duraiswamy Jeyaraj, Vishal Pendharkar, Kakaly Ghosh, Isaac H Virshup, Vithya Manoharan, Esther Hq Ong, Kanda Sangthongpitag, Jeffrey Hill, Enrico Petretto, Thomas Keller, May Ann Lee, Alex Matter, David M Virshup Oncogene
25 Jun 2015 BMRC Experimental Drug Development Centre Discovery and Optimization of a Porcupine Inhibitor Athisayamani Jeyaraj Duraiswamy, May Ann Lee, Babita Madan, Shi Hua Ang, Eldwin Sum Wai Tan, Wei Wen Vivien Cheong, Zhiyuan Ke, Vishal Pendharkar, Li Jun Ding, Yun Shan Chew, Vithya Manoharan, Kanda Sangthongpitag, Jenefer Alam, Anders Poulsen, Soo Yei Ho, David Virshup, Thomas Hugo Keller Journal of Medicinal Chemistry
29 May 2015 BMRC Experimental Drug Development Centre A Pharmacophore Model for Wnt/Porcupine Inhibitors and its Use for Drug Design Grace Ruiting Lin, Vivien Wei Wen Cheong, Zhiyuan Ke, May Ann Lee, Thomas Keller, Anders Poulsen, Soo Yei Ho, Weiling Wang, Jenefer Alam, Duraiswamy Jeyaraj, Shi Hua Ang, Eldwin Sum Wai Tan Journal of Chemical Information and Modeling
6 Jun 2014 BMRC Institute of Bioengineering and Nanotechnology Therapeutic effect of a multi-targeted imidazolium compound in hepatocellular carcinoma Began Gopalan, Karthikeyan Narayanan, Zhiyuan Ke, Ting Lu, Yugen Zhang, Lang Zhuo Biomaterials