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21 Jul 2021 SERC Institute for Infocomm Research KG4SL: knowledge graph neural network for synthetic lethality prediction in human cancers (Pending publish) Shike Wang, Fan Xu, Yunyang Li, Jie Wang, Ke Zhang, Yong Liu, Min Wu, Jie Zheng Bioinformatics
12 Mar 2021 BMRC Institute of Bioengineering and Bioimaging Granzyme B PET Imaging of Combined Chemotherapy and Immune Checkpoint Inhibitor Therapy in Colon Cancer (Pending publish) Julian L Goggi, Siddesh V Hartimath, Tan Yun Xuan, Shivashankar Khanapur, Beverly Jieu, Hui Xian Chin, Boominathan Ramasamy, Peter Cheng, Tang Jun Rong, Yong Fui Fong, Tsz Ying Yuen, Rasha Msallam, Ann-Marie Chacko, Laurent Renia, Charles Johannes, You Yi Hwang, Edward G Robins Molecular Imaging and Biology
1 Mar 2021 BMRC Institute of Molecular and Cell Biology sORF-Encoded MicroPeptides: New players in inflammation, metabolism, and precision medicine Ying Chen, Lena Ho, Vinay Tergaonkar Cancer Letters
23 Feb 2021 BMRC Institute of Bioengineering and Bioimaging Patient-Derived Nasopharyngeal Cancer Organoids for Disease Modeling and Radiation Dose Optimization (Pending publish) Sasidharan Swarnalatha Lucky, Martin Law, Ming Hong Lui, Jamie Mong, Junli Shi, Sidney Yu, Do Kun Yoon, Shih Kien Djeng, Jiguang Wang, Chwee Ming Lim, Min Han Tan Frontiers in Oncology
20 Feb 2021 SERC Institute for Infocomm Research Graph contextualized attention network for predicting synthetic lethality in human cancers (Pending publish) Yahui Long, Min Wu, Yong Liu, Jie Zheng, Chee-Keong Kwoh, Jiawei Luo, Xiao-Li Li Bioinformatics
27 Aug 2020 SERC Institute for Infocomm Research Multi-Phase Cross-modal Learning for Noninvasive Gene Mutation Prediction in Hepatocellular Carcinoma Jiapan Gu, Ziyuan Zhao, Zeng Zeng, Yuzhe Wng, Zhengyiren Qiu, Bharadwaj Veeravalli, Brian Kim Poh Goh, Glenn Kunnath Bonney, Krishnakumar Madhavan, Chan Wan Ying, Lim Kheng Choon, Thng Choon Hua, Pierce KH Chow 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
21 Aug 2020 SERC Institute for Infocomm Research Exploring the Inter-voxel Information in Pharmacokinetic Maps for Cervical Carcinoma Prediction Zhuo ZHANG IEEE conf. EMBS 2020
25 Mar 2020 BMRC Bioinformatics Institute A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Li Ren Kong, Tuan Zea Tan, Nicholas L. Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel S W Tan, Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S. Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline S. J. Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H. Philip Koeffler, Soo Chin Lee, Dennis Kappei, Huyhn The Hung, Boon Cher Goh Nature Communications
7 Jan 2020 BMRC Bioprocessing Technology Institute Preclinical Activity of Embryonic Annexin A2-Specific Chimeric Antigen Receptor T Cells Against Ovarian Cancer Leonard Leong, Heng Liang Tan, Simeon Cua, Kylie Su Mei Yong, Qingfeng Chen, Andre Choo International Journal of Molecular Sciences
21 Dec 2019 BMRC Singapore Bioimaging Consortium Ultrasound Guided Optoacoustic Tomography in Assessment of Tumor Margins for Lumpectomies Yonggeng Goh, Ghayathri Balasundaram, Mohesh Moothanchery, Amalina Attia, Xiuting Li, Hann Qian Lim, Neal C. Burton, Yi Qiu, Thomas Choudary Putti, Ching Wan Chan, Philip Iau, Shaik Ahmad Buhari, Mikael Hartman, Siau Wei Tang, Celene Wei Qi Ng, Yiong Huak Chan, Felicity Jane Pool, Premilla Pillay, Wynne Chua, Jeevesh Kapur, Pooja Jagmohan, Eide Sterling, Swee Tian Quek, Malini Olivo Translational Oncology
13 Dec 2019 BMRC Institute of Molecular and Cell Biology Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy Ekta Khattar, Kyaw Ze Ya Maung, Chen Li Chew, Arkasubhra Ghosh, Michelle Meng Huang Mok, Pei Lee, Jun Zhang, Wei Hong Jeff Chor, Gökhan Cildir, Chelsia Qiuxia Wang, Nur Khairiah Mohd-Ismail, Desmond Wai Loon Chin, Soo Chin Lee, Henry Yang, Yong-Jae Shin, Do-Hyun Nam, Liming Chen, Alan Prem Kumar, Lih Wen Deng, Masahito Ikawa, Jayantha Gunaratne, Motomi Osato, Vinay Tergaonkar Nature Communications
11 Nov 2019 BMRC Bioinformatics Institute Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1 Umesh Kalathiya, Monikaben Padariya, Kamila Pawlicka, Chandra S. Verma, Douglas Houston, Ted R. Hupp, Javier Antonio Alfaro International Journal of Molecular Sciences
18 Oct 2019 SERC Institute of Materials Research and Engineering Self-Healable, Fast Responsive Poly(ω-Pentadecalactone) Thermogelling System for Effective Liver Cancer Therapy Huihui Shi, Hong Chi, Zheng Luo, Lu Jiang, Xian Jun Loh, Chaobin He, Zibiao Li Frontiers in Chemistry
25 Sep 2019 BMRC Bioinformatics Institute c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression Wen Jing Sim, Prasanna Vasudevan Iyengar, Dilraj Lama, Sara Kit Leng Lui, Hsien Chun Ng, Lior Haviv-Shapira, Eytan Domany, Dennis Kappei, Tuan Zea Tan, Azad Saie, Patrick William Jaynes, Chandra Shekhar Verma, Hong Koo Ha, Camelia Radulescu, Peter ten Dijke, Pieter Johan Adam Eichhorn, Jean Paul Thiery, Alan Prem Kumar, Mathieu Rouanne Nature Communications
12 Sep 2019 BMRC Bioinformatics Institute PI3K Catalytic Subunits α and β Modulate Cell Death and IL-6 Secretion Induced by Talc Particles in Human Lung Carcinoma Cells Nicola Michelle Bougen-Zhukov, Yin Yeng Lee, Jia-Ying Joey Lee, Pyng Lee, Lit-Hsin Loo American Journal of Respiratory Cell and Molecular Biology
5 Sep 2019 BMRC Genome Institute of Singapore A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters Deniz Demircioğlu, Engin Cukuroglu, Martin Kindermans, Tannistha Nandi, Claudia Calabrese, Nuno A. Fonseca, André Kahles, Kjong-Van Lehmann, Oliver Stegle, Alvis Brazma, Angela N. Brooks, Gunnar Rätsch, Patrick Tan, Jonathan Göke Cell
15 Aug 2019 BMRC Bioinformatics Institute Therapeutic anti-cancer activity of antibodies targeting sulfhydryl bond constrained epitopes on unglycosylated RON receptor tyrosine kinase Le-Ann Hwang, Fernando Jose Ferrer, Xin Yu Koh, Xiao Hui Koh, Sit Aishah Binte Rahmat, Dilray Lama, David P. Lane Oncogene
7 Aug 2019 BMRC Bioprocessing Technology Institute In vivo surveillance and elimination of teratoma‐forming human embryonic stem cells with monoclonal antibody 2448 targeting annexin A2 Heng Liang Tan, Bao Zhu Tan, Winfred Xi Tai Goh, Simeon Cua, Andre Choo Biotechnology and Bioengineering
28 May 2019 BMRC Bioinformatics Institute Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast Cancer Denis M. Collins, Neil T. Conlon, Srinivasaraghavan Kannan, Chandra S. Verma, Lisa D. Eli, Alshad S. Lalani, John Crown Cancers
27 May 2019 BMRC Singapore Bioimaging Consortium Identifying non-small-cell lung tumours bearing the T790M EGFR TKI resistance mutation using PET Julian L. Goggi, Anna Haslop, Boominathan Ramasamy, Peter Cheng, Lingfan Jiang, Vanessa Soh, Edward G. Robins Journal of Labelled Compounds and Radiopharmaceuticals
1 Mar 2019 BMRC p53 Laboratory SHON Expression Predicts Response and Relapse Risk of Breast Cancer Patients After Anthracycline-Based Combination Chemotherapy or Tamoxifen Treatment Longxin Chen, Runlin Z. Ma, Wenming Cao, Xiaojia Wang, Yan Li, Jo K. Perry, Mohammed Aleskandarany, Christopher C. Nolan, Emad A. Rakha, Peter E. Lobie, Stephen Y. T. Chan, Ian O. Ellis, Le-Ann Hwang, David P. Lane, Andrew R. Green, Dong-Xu Liu, Tarek M. A. Abdel-Fatah, Reuben J. Broom, Jun Lu, Paul M. Moseley, Baiqu Huang, Lili Li, Suling Liu British Journal of Cancer
15 Feb 2019 BMRC Singapore Institute of Food and Biotechnology Innovation Defining rules for cancer cell proliferation in TRAIL stimulation William Deveaux, Kentaro Hayashi, Kumar Selvarajoo NPJ Systems Biology and Applications
30 Jan 2019 BMRC Institute of Medical Biology One rogue agent suffices for genomic chaos Katherine E. Larrimore, Giulia Rancati Nature
1 Jan 2019 BMRC Singapore Institute of Food and Biotechnology Innovation Defining rules for cancer cell proliferation in TRAIL stimulation William Deveaux, Kentaro Hayashi, Kumar Selvarajoo NPJ Systems Biology and Applications
28 Nov 2018 BMRC Institute of Bioengineering and Nanotechnology Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-base DNA Aptamers Targeting Cancer Cells Kazunobu Futami, Michiko Kimoto, Yun Wei Shermane Lim, Ichiro Hirao Molecular Therapy Nucleic Acids
24 Sep 2018 BMRC p53 Laboratory Ultrasensitive dynamic light scattering based nanobiosensor for rapid anticancer drug screening Xin Ting Zheng, Walter L. Goh, Peter Yeow, David P. Lane, Farid J. Ghadessy, Yen Nee Tan Sensors and Actuators B: Chemical
21 Feb 2018 BMRC Institute of Medical Biology Recent Advances in Lgr5+ Stem Cell Research Carly Leung, Si Hui Tan, Nick Barker Trends in Cell Biology
8 Jan 2018 BMRC Institute of Medical Biology Chapter Two - Wnt Signaling in Adult Epithelial Stem Cells and Cancer Si Hui Tan, Nick Barker Progress in Molecular Biology and Translational Science
31 Oct 2017 BMRC Singapore Institute for Clinical Sciences Effect of Weight Gain and Weight Loss on In Vivo Colonocyte Proliferation Rate in People with Obesity Faidon Magkos, Shelby Sullivan, Mark Fitch, Gordon Smith, Elisa Fabbrini, Bettina Mittendorfer, Marc Hellerstein, Samuel Klein Obesity
27 Jun 2017 BMRC p53 Laboratory Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity Shunsheng Zheng, Xin Yu Koh, Hui Chin Goh, Siti Aishah B. Rahmat, Le-Ann Hwang, David P. Lane Cancer Research
13 Mar 2017 BMRC Singapore Institute for Clinical Sciences Plasma-free amino acid profiles are predictors of cancer and diabetes development Xinyan BI, Christiani Jeyakumar Henry Nutrition & Diabetes
25 Feb 2016 BMRC Institute of Medical Biology Organoids as an in vitro model of human development and disease Aliya Fatehullah, Si Hui Tan, Nick Barker Nature Cell Biology
26 Nov 2015 BMRC Institute of Bioengineering and Nanotechnology Collaboration of 3D Context and Extracellular Matrix in the Development of Glioma Stemness in a 3D Model Beng Ti Ang, Nina K.L. Ma, Jia Kai Lim, M.F. Leong, E. Sandanaraj, Carol Tang, Andrew C.A. Wan Biomaterials
13 Aug 2015 Others Other Institutions Understanding Domains of Health-related Quality of Life Concerns of Singapore Chinese Patients with Advanced Cancer: A Qualitative Analysis GL Lee, GSY Pang, R Akhileswaran, MY Ow, GKT Fan, CCF Wong, HL Wee, YB Cheung Supportive Care in Cancer
10 Aug 2015 BMRC Experimental Drug Development Centre Wnt addiction of genetically defined cancers reversed by PORCN inhibition Babita Madan, Zhiyuan Ke, Nathan Harmston, Soo Yei Ho, Frois Ashley Oliver, Jenefer Alam, Duraiswamy Jeyaraj, Vishal Pendharkar, Kakaly Ghosh, Isaac H Virshup, Vithya Manoharan, Esther Hq Ong, Kanda Sangthongpitag, Jeffrey Hill, Enrico Petretto, Thomas Keller, May Ann Lee, Alex Matter, David M Virshup Oncogene
14 Jul 2015 BMRC Genome Institute of Singapore Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity Ruan Yijun, Jacques Pierre-Etienne, So Jimmy B.Y., Ruan Xiaoan, Yeoh Khay Guan, Tan Patrick, Sung Wing-Kin, Hunziker Walter, Yao Fei, Kausalya Jaya P., Sia Yee Yen, Teo Audrey S.M, Lee Wah Heng, Ong Alicia G.M., Zhang Zhengshui, Tan Joanna H.J., Li Guoliang, Bertrand Dennis, Liu Xinliang, Poh Huay Mei, Guan Peiyong, Zhu Feng, Pathiraja Thushangi Nadeera Pathiraja, Ariyatne Pramila N., Rao Jaideepraj, Woo Xing Yi, Cai Shaojiang, Mulawadi Fabianus H., Poh Wan Ting, Veeravalli Lavanya, Chan Chee Seng, Lim Seong Soo, Leong See Ting, Neo Say Chuan, Choi Poh Sum D., Chew Elaine G.Y., Nagarajan Niranjan, Hillmer Axel M. Cell Reports
25 Jun 2015 BMRC Experimental Drug Development Centre Discovery and Optimization of a Porcupine Inhibitor Athisayamani Jeyaraj Duraiswamy, May Ann Lee, Babita Madan, Shi Hua Ang, Eldwin Sum Wai Tan, Wei Wen Vivien Cheong, Zhiyuan Ke, Vishal Pendharkar, Li Jun Ding, Yun Shan Chew, Vithya Manoharan, Kanda Sangthongpitag, Jenefer Alam, Anders Poulsen, Soo Yei Ho, David Virshup, Thomas Hugo Keller Journal of Medicinal Chemistry
25 Oct 2014 Others Other Institutions Quality of life domains important and relevant to family caregivers of advanced cancer patients in an Asian population: a qualitative study Geok Ling Lee, Yin Bun Cheung Quality of Life Research
8 Aug 2013 BMRC Institute of Molecular and Cell Biology Cdks, cyclins and CKIs: roles beyond cell cycle regulation Philipp Kaldis, Shuhui Lim Development
8 Aug 2013 BMRC Institute of Molecular and Cell Biology Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia (Pending publish) Qi Zeng, Jung Eun Park, Hiu Fung Yuen, Jian Biao Zhou, Abdul Qader O. Al-aidaroos, Ke Guo, Peter J. Valk, Shu Dong Zhang, Wee Joo Chng, Cheng William Hong, Ken Mills EMBO Molecular Medicine
1 Sep 2011 BMRC Institute of Medical Biology Gastrointestinal stem cells in self-renewal and cancer S. Adelia Lin, Nick Barker Journal of Gastroenterology