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25 Jun 2024
BMRC
Institute of Molecular and Cell Biology
Machine Learning-Enhanced Extraction of Biomarkers for High-Grade Serous Ovarian Cancer from Proteomics Data
(Pending publish)
Senuri De Silva,
Asfa Alli-Shaik,
Jayantha Gunaratne
Scientific Data
10 Jun 2024
BMRC
Institute of Molecular and Cell Biology
Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
LeLe Wu,
Zheng Zhao,
Yong Jae Shin,
Yiyun Yin,
Anandhkumar Raju,
Thamil Selvan Vaiyapuri,
Khaireen Idzham,
Miseol Son,
Yeri Lee,
Jason K. Sa,
Joelle Yi Heng Chua,
Bilal Unal,
You Zhai,
Wenhua Fan,
Lijie Huang,
Huimin Hu,
Jayantha Gunaratne,
Do-Hyun Nam,
Tao Jiang,
Vinay Tergaonkar
Nature Cell Biology
15 Apr 2024
Others
Experimental Drug Development Centre
Cytotoxic activity and cell specificity of a novel LHRH peptide drug conjugate, D-Cys6-LHRH vedotin, against ovarian cancer cell lines
Subramanyam Vankadara,
Zhiyuan Ke,
Sifang Wang,
Sin Yun Foo,
Jayantha Gunaratne,
May Ann Lee,
Xiaoying Koh,
C. S. Brian Chia
Chemical Biology & Drug Design
11 Apr 2024
BMRC
Institute of Molecular and Cell Biology
FlexStat: combinatory differentially expressed protein extraction
Senuri De Silva,
Asfa Alli-Shaik,
Jayantha Gunaratne
Bioinformatics Advances
27 Nov 2023
BMRC
Institute of Molecular and Cell Biology
Potential relevance of salivary legumain for the clinical diagnostic of hand, foot, and mouth disease
Yong Wah Tan,
Fiona Mei Shan Teo,
Siok Ghee Ler,
Asfa Alli‐Shaik,
Min Nyo,
Chia Yin Chong,
Natalie Woon Hui Tan,
Robert Y. L. Wang,
Jayantha Gunaratne,
Justin Jang Hann Chu
Journal of Medical Virology
28 Sep 2023
BMRC
Institute of Molecular and Cell Biology
Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting
Thiruma V Arumugam,
Asfa Alli-Shaik,
Elisa A Liehn,
Sharmelee Selvaraji,
Luting Poh,
Vismitha Rajeev,
Yoonsuk Cho,
Yongeun Cho,
Jongho Kim,
Joonki Kim,
Hannah LF Swa,
David Tan Zhi Hao,
Chutima Rattanasopa,
David Yang-Wei Fann,
David Castano Mayan,
Gavin Yong-Quan Ng,
Sang-Ha Baik,
Karthik Mallilankaraman,
Mathias Gelderblom,
Grant R Drummond,
Christopher G Sobey,
Brian K Kennedy,
Roshni R Singaraja,
Mark P Mattson,
Dong-Gyu Jo,
Jayantha Gunaratne
eLife
28 Sep 2022
BMRC
Institute of Molecular and Cell Biology
System-wide vitreous proteome dissection reveals impaired sheddase activity in diabetic retinopathy
Asfa Alli-Shaik,
Beiying Qiu,
Siew Li Lai,
Ning Cheung,
Gavin Tan,
Suat Peng Neo,
Alison Tan,
Chiu Ming Gemmy Cheung,
Wanjin Hong,
Tien Yin Wong,
Xiaomeng Wang,
Jayantha Gunaratne
Theranostics
5 May 2022
BMRC
Institute of Molecular and Cell Biology
Phosphoproteomics Unravel HBV Triggered Rewiring of Host Phosphosignaling Events
Zijie Lim,
Nur Khairiah Binte Mohd-Ismail,
Evelyn Png,
Ching Wooen Sze,
Qifeng Lin,
Wanjin Hong,
Seng Gee Lim,
Yee-Joo Tan,
Jayantha Gunaratne
International Journal of Molecular Sciences
28 Jan 2020
BMRC
Institute of Molecular and Cell Biology
Comprehensive Proteomic Characterization Reveals Subclass-Specific Molecular Aberrations within Triple-negative Breast Cancer
Max Kosok,
Asfa Alli-Shaik,
Boon Huat Bay,
Jayantha Gunaratne
iScience
13 Dec 2019
BMRC
Institute of Molecular and Cell Biology
Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy
Ekta Khattar,
Kyaw Ze Ya Maung,
Chen Li Chew,
Arkasubhra Ghosh,
Michelle Meng Huang Mok,
Pei Lee,
Jun Zhang,
Wei Hong Jeff Chor,
Gökhan Cildir,
Chelsia Qiuxia Wang,
Nur Khairiah Mohd-Ismail,
Desmond Wai Loon Chin,
Soo Chin Lee,
Henry Yang,
Yong-Jae Shin,
Do-Hyun Nam,
Liming Chen,
Alan Prem Kumar,
Lih Wen Deng,
Masahito Ikawa,
Jayantha Gunaratne,
Motomi Osato,
Vinay Tergaonkar
Nature Communications
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