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Publication date Communities Collections Article title Author(s) Journal/Conference
26 Jan 2021 BMRC Institute of Molecular and Cell Biology A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis Si Hui Tan, Phyllis Phuah, Liang Thing Tan, Swathi Yada, Jasmine Goh, Lucian B. Tomaz, Magdalene Chua, Esther Wong, Bernett Lee, Nick Barker Cell Reports
26 Jan 2021 BMRC Institute of Molecular and Cell Biology A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells Kazuhiro Murakami, Yumi Terakado, Kikue Saito, Yoshie Jomen, Haruna Takeda, Masanobu Oshima, Nick Barker Proceedings of the National Academy of Sciences
5 Feb 2020 BMRC Institute of Medical Biology AQP5 enriches for stem cells and cancer origins in the distal stomach Si Hui Tan, Yada Swathi, Shawna Tan, Jasmine Goh, Ryo Seishima, Kazuhiro Murakami, Masanobu Oshima, Toshikatsu Tsuji, Phyllis Phuah, Liang Thing Tan, Esther Wong, Aliya Fatehullah, Taotao Sheng, Shamaine Wei Ting Ho, Heike I. Grabsch, Supriya Srivastava, Ming Teh, Simon L. I. J. Denil, Seri Mustafah, Patrick Tan, Asim Shabbir, Jimmy So, Khay Guan Yeoh, Nick Barker Nature
26 Nov 2019 BMRC Institute of Molecular and Cell Biology Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development Ryo Seishima, Carly Leung, Swathi Yada, Katzrin Bte Ahmed Murad, Liang Thing Tan, Amin Hajamohideen, Si Hui Tan, Hideki Itoh, Kazuhiro Murakami, Yoshihiro Ishida, Satoshi Nakamizo, Yusuke Yoshikawa, Esther Wong, Nick Barker Nature Communications
8 Jul 2019 BMRC Institute of Medical Biology The Function of Lgr5+ Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo Dustin Flanagan, Nick Barker, Matthias Ernst, Elizabeth Vincan, Toby Phesse Biomedicines
17 Jun 2019 BMRC Institute of Medical Biology Distinct localization of mature hgf from its precursor form in developing and repairing the stomach Nawaphat Jangphattananont, Hiroki Sato, Ryu Imamura, Katsuya Sakai, Yumi Terakado, Kazuhiro Murakami, Nick Barker, Hiroko Oshima, Masanobu Oshima, Junichi Takagi, Yukinari Kato, Seiji Yano, Kunio Matsumoto International Journal of Molecular Sciences
28 May 2019 BMRC Institute of Medical Biology Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo Nick Barker, Shawn Hoon, Yuezhen Xue, Pingping He, Teena Thakur, Shifana Raja Abdeen, Priadarsini Maruthappan, Farid J. Ghadessy, David P. Lane Cancer Research
8 Jan 2019 BMRC Institute of Medical Biology Frizzled-7 is required for Wnt signaling in gastric tumors with and without APC mutations Dustin J. Flanagan, Nick Barker, Natasha S. Di Costanzo, Elizabeth A. Mason, Austin Gurney, Valerie S. Meniel, Sarah Koushyar, Chloe R. Austin, Matthias Ernst, Helen B. Pearson, Alex Boussioutas, Hans Clevers, Toby J. Phesse, Elizabeth Vincan Cancer Research
21 Feb 2018 BMRC Institute of Medical Biology Recent Advances in Lgr5+ Stem Cell Research Carly Leung, Si Hui Tan, Nick Barker Trends in Cell Biology
8 Jan 2018 BMRC Institute of Medical Biology Chapter Two - Wnt Signaling in Adult Epithelial Stem Cells and Cancer Si Hui Tan, Nick Barker Progress in Molecular Biology and Translational Science
2 Aug 2017 BMRC Institute of Medical Biology Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo Dustin J. Flanagan, Nick Barker, Cameron Nowell, Hans Clevers, Matthias Ernst, Toby J. Phesse, Elizabeth Vincan Disease Models & Mechanisms
5 Jun 2017 BMRC Institute of Medical Biology Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach Marc Leushacke, Si Hui Tan, Angeline Wong, Yada Swathi, Amin Hajamohideen, Liang Thing Tan, Jasmine Goh, Esther Wong, Simon L. I. J. Denil, Kazuhiro Murakami, Nick Barker Nature Cell Biology
26 Feb 2016 BMRC Institute of Medical Biology Quantifying Lgr5-positive stem cell behaviour in the pyloric epithelium Marc Leushacke, Nick Barker, Carmen Pin Scientific Reports
25 Feb 2016 BMRC Institute of Medical Biology Organoids as an in vitro model of human development and disease Aliya Fatehullah, Si Hui Tan, Nick Barker Nature Cell Biology
9 Sep 2015 BMRC Institute of Medical Biology Ovary and fimbrial stem cells: biology, niche and cancer origins Annie Ng, Nick Barker Nature Reviews Molecular Cell Biology
3 Aug 2015 BMRC Institute of Medical Biology E-cadherin can limit the transforming properties of activating β-catenin mutations Sujata Biswas, Simon Leedham, David J. Huels, Rachel A Ridgway, Sorina Radulescu, Marc Leushacke, Andrew D. Campbell, Stefano Serra, Runjan Chetty, Guenievre Moreauz, Lee Parry, James Matthews, Fei Song, Ann Hedley, Gabriela Kalna, Fatih Ceteci, Karen R. Reed, Valerie S. Meniel, Aoife Maguire, Brendan Doyle, Ola Söderberg, Nick Barker, Alastair Watson, Lionel Larue, Alan R. Clarke, Owen J. Sansom The EMBO Journal
22 Jul 2015 BMRC Institute of Medical Biology Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice Amanda M. Goh, Yuezhen Xue, Marc Leushacke, Ling Li, Julin S. Wong, Poh Cheang Chiam, Siti Aishah Rahmat, Michael B. Mann, Karen M. Mann, Nick Barker, Guillermina Lozano, Tamara Terzian, David P. Lane Oncotarget
10 Mar 2015 BMRC Institute of Medical Biology Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium Katja Horvay, Thierry Jarde, Franca Casagranda, Victoria M Perreau, Katharina Haigh, Christian M Nefzger, Reyhan Akhtar, Thomas Gridley, Geert Berx, Jody J Haigh, Nick Barker, Jose M Polo, Gary R Hime, Helen E Abud The EMBO Journal
13 Sep 2014 BMRC Institute of Medical Biology Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5+ stem cells Dustin J Flanagan, Toby J Phesse, Nick Barker, Jordane Malaterre, Daniel E. Stange, Cameron J. Nowell, Scott A. Currie, Jarel T.S. Saw, Eva Beuchert, Robert G. Ramsay, Owen J. Sansom, Matthias Ernst, Hans Clevers, Elizabeth Vincan, Renate H.M. Schwab, Nancy Amin Stem Cell Reports
6 Jul 2014 BMRC Institute of Medical Biology Lgr5 Marks Stem/Progenitor Cells in Ovary and Tubal Epithelia Annie Ng, Shawna Tan, Gurmit Singh, Pamela Rizk, Yada Swathi, Tuan Zea Tan, Ruby Yun-Ju Huang, Marc Leushacke, Nick Barker Nature Cell Biology
19 May 2014 BMRC Institute of Medical Biology Ex vivo culture of the intestinal epithelium: strategies and applications Marc Leushacke, Nick Barker Gut
15 Jan 2014 BMRC Institute of Medical Biology Chapter Three - Intestinal Stem Cells and Their Defining Niche David Wei Min Tan, Nick Barker Current Topics in Developmental Biology
11 Dec 2013 BMRC Institute of Medical Biology Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration Nick Barker Nature Reviews Molecular Cell Biology
24 Oct 2013 BMRC Institute of Medical Biology Lgr5+ Gastric Stem Cells Divide Symmetrically to Effect Epithelial Homeostasis in the Pylorus Annie Ng, Marc Leushacke, Joerg Galle, Markus Loeffler, Nick Barker Cell Reports
28 Jun 2013 BMRC Institute of Medical Biology Lgr proteins in epithelial stem cell biology Nick Barker, Shawna Tan, Hans Clevers Development
30 Nov 2012 BMRC Institute of Medical Biology Stem cell reprogramming as a driver of basal cell carcinoma David W. M. Tan, Nick Barker Nature Cell Biology
20 Sep 2012 BMRC Institute of Medical Biology Lgr5+ve Stem/Progenitor Cells Contribute to Nephron Formation during Kidney Development Nick Barker, Maarten B. Rookmaaker, Pekka Kujala, Annie Ng, Marc Leushacke, Hugo Snippert, Marc van de Wetering, Shawna Tan, Johan H. Van Es, Meritxell Huch, Richard Poulsom, Marianne C. Verhaar, Peter J. Peters, Hans Clevers Cell Reports
1 Sep 2011 BMRC Institute of Medical Biology Gastrointestinal stem cells in self-renewal and cancer S. Adelia Lin, Nick Barker Journal of Gastroenterology