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11 Jul 2022
BMRC
Institute of Molecular and Cell Biology
Organoid systems for recapitulating the intestinal stem cell niche and modeling disease in vitro
Hui Yi Grace Lim,
Lana Kostic,
Nick Barker
Advances in Stem Cells and their Niches
18 May 2022
BMRC
Institute of Molecular and Cell Biology
Targeted ablation of Lgr5-expressing intestinal stem cells in diphtheria toxin receptor-based mouse and organoid models
Hui Yi Grace Lim,
Swathi Yada,
Nick Barker
STAR Protocols
22 Nov 2021
BMRC
Institute of Molecular and Cell Biology
A key malignant switch in skin SCC
Hui Yi Grace Lim,
Nick Barker
Nature Cancer
26 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis
Si Hui Tan,
Phyllis Phuah,
Liang Thing Tan,
Swathi Yada,
Jasmine Goh,
Lucian B. Tomaz,
Magdalene Chua,
Esther Wong,
Bernett Lee,
Nick Barker
Cell Reports
26 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells
Kazuhiro Murakami,
Yumi Terakado,
Kikue Saito,
Yoshie Jomen,
Haruna Takeda,
Masanobu Oshima,
Nick Barker
Proceedings of the National Academy of Sciences
5 Feb 2020
BMRC
Institute of Medical Biology
AQP5 enriches for stem cells and cancer origins in the distal stomach
Si Hui Tan,
Yada Swathi,
Shawna Tan,
Jasmine Goh,
Ryo Seishima,
Kazuhiro Murakami,
Masanobu Oshima,
Toshikatsu Tsuji,
Phyllis Phuah,
Liang Thing Tan,
Esther Wong,
Aliya Fatehullah,
Taotao Sheng,
Shamaine Wei Ting Ho,
Heike I. Grabsch,
Supriya Srivastava,
Ming Teh,
Simon L. I. J. Denil,
Seri Mustafah,
Patrick Tan,
Asim Shabbir,
Jimmy So,
Khay Guan Yeoh,
Nick Barker
Nature
26 Nov 2019
BMRC
Institute of Molecular and Cell Biology
Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
Ryo Seishima,
Carly Leung,
Swathi Yada,
Katzrin Bte Ahmed Murad,
Liang Thing Tan,
Amin Hajamohideen,
Si Hui Tan,
Hideki Itoh,
Kazuhiro Murakami,
Yoshihiro Ishida,
Satoshi Nakamizo,
Yusuke Yoshikawa,
Esther Wong,
Nick Barker
Nature Communications
8 Jul 2019
BMRC
Institute of Medical Biology
The Function of Lgr5+ Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo
Dustin Flanagan,
Nick Barker,
Matthias Ernst,
Elizabeth Vincan,
Toby Phesse
Biomedicines
17 Jun 2019
BMRC
Institute of Medical Biology
Distinct localization of mature hgf from its precursor form in developing and repairing the stomach
Nawaphat Jangphattananont,
Hiroki Sato,
Ryu Imamura,
Katsuya Sakai,
Yumi Terakado,
Kazuhiro Murakami,
Nick Barker,
Hiroko Oshima,
Masanobu Oshima,
Junichi Takagi,
Yukinari Kato,
Seiji Yano,
Kunio Matsumoto
International Journal of Molecular Sciences
28 May 2019
BMRC
Institute of Medical Biology
Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo
Nick Barker,
Shawn Hoon,
Yuezhen Xue,
Pingping He,
Teena Thakur,
Shifana Raja Abdeen,
Priadarsini Maruthappan,
Farid J. Ghadessy,
David P. Lane
Cancer Research
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