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13 Mar 2025
BMRC
Genome Institute of Singapore
A systematic benchmark of Nanopore long-read RNA sequencing for transcript-level analysis in human cell lines
Ying Chen,
Nadia M. Davidson,
Yuk Kei Wan,
Fei Yao,
Yan Su,
Hasindu Gamaarachchi,
Andre Sim,
Harshil Patel,
Hwee Meng Low,
Christopher Hendra,
Laura Wratten,
Christopher Hakkaart,
Chelsea Sawyer,
Viktoriia Iakovleva,
Puay Leng Lee,
Lixia Xin,
Hui En Vanessa Ng,
Jia Min Loo,
Xuewen Ong,
Hui Qi Amanda Ng,
Jiaxu Wang,
Wei Qian Casslynn Koh,
Suk Yeah Polly Poon,
Dominik Stanojevic,
Hoang-Dai Tran,
Kok Hao Edwin Lim,
Shen Yon Toh,
Philip Andrew Ewels,
Huck-Hui Ng,
N. Gopalakrishna Iyer,
Alexandre Thiery,
Wee Joo Chng,
Leilei Chen,
Ramanuj DasGupta,
Mile Sikic,
Yun-Shen Chan,
Boon Ooi Patrick Tan,
Yue Wan,
Wai Leong Tam,
Qiang Yu,
Chiea Chuan Khor,
Torsten Wüstefeld,
Alexander Lezhava,
Ploy N. Pratanwanich,
Michael I. Love,
Wee Siong Sho Goh,
Sarah B. Ng,
Alicia Oshlack,
,
N. Gopalakrishna Iyer,
Qiang Yu,
Jonathan Göke
Nature Methods
25 Feb 2025
BMRC
Singapore Immunology Network
Atypical memory B cells acquire Breg phenotypes in hepatocellular carcinoma
Shi Yong Neo,
Timothy Wai Ho Shuen,
Shruti Khare,
Joni Chong,
Maichan Lau,
Niranjan Shirgaonkar,
Levene Chua,
Junzhe Zhao,
Keene Lee,
Charmaine Tan,
Rebecca Ba,
Janice Lim,
Joelle Chua,
Hui Shi Cheong,
Hui Min Chai,
Chung Yip Chan,
Alexander Yaw Fui Chung,
Peng Chung Cheow,
Prema Raj Jeyaraj,
Jin Yao Teo,
Ye Xin Koh,
Aik Yong Chok,
Pierce Kah Hoe Chow,
Brian Goh,
Wei Keat Wan,
Wei Qiang Leow,
Tracy Jie Zhen Loh,
Po Yin Tang,
Jayanthi Karunanithi,
Nye Thane Ngo,
Tony Kiat Hon Lim,
Shengli Xu,
Ramanuj DasGupta,
Han Chong Toh,
Kong-Peng Lam
JCI Insight
17 Jun 2024
BMRC
Institute of Molecular and Cell Biology
Iron-(Fe3+)-Dependent Reactivation of Telomerase Drives Colorectal Cancers
Raghuvaran Shanmugam,
Prativa Majee,
Wei Shi,
Mert B. Ozturk,
Thamil S. Vaiyapuri,
Khaireen Idzham,
Anandhkumar Raju,
Seung H. Shin,
Kerem Fidan,
Joo-Leng Low,
Joelle Y.H. Chua,
Yap C. Kong,
Ong Y. Qi,
Emile Tan,
Aik Y. Chok,
Isaac Seow-En,
Ian Wee,
Dominique C. Macalinao,
Dawn Q. Chong,
Hong Y. Chang,
Fiona Lee,
Wei Q. Leow,
Maki Murata-Hori,
Zhang Xiaoqian,
Chia Shumei,
Chris S.H. Tan,
Ramanuj DasGupta,
Iain B. Tan,
Vinay Tergaonkar
Cancer Discovery
14 Jun 2022
BMRC
Institute of Molecular and Cell Biology
Identification of mechanism of cancer-cell-specific reactivation of hTERT offers therapeutic opportunities for blocking telomerase specifically in human colorectal cancer
Semih Can Akıncılar,
Joelle Yi Heng Chua,
Qin Feng NG,
Claire Hian Tzer Chan,
Zahra Eslami-S,
Kaijing Chen,
Joo-Leng Low,
Surendar Arumugam,
Luay Aswad,
Clarinda Chua,
Iain Beehuat Tan,
Ramanuj DasGupta,
Melissa Jane Fullwood,
Vinay Tergaonkar
Nucleic Acids Research
18 Jan 2022
BMRC
Institute of Molecular and Cell Biology
Genome-wide screens identify specific drivers of mutant hTERT promoters
Raghuvaran Shanmugam,
Mert Burak Ozturk,
Joo-Leng Low,
Semih Can AKINCILAR,
Joelle Yi Heng Chua,
Matan Thangavelu Thangavelu,
Giridharan Periyasamy,
Ramanuj DasGupta,
Vinay Tergaonkar
Proceedings of the National Academy of Sciences
15 May 2021
BMRC
Institute of Molecular and Cell Biology
Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction
Joo-Leng Low,
Weina Du,
Tenzin Gocha,
Gokce Oguz,
Xiaoqian Zhang,
Ming Wei Chen,
Srdan Masirevic,
Daniel Guo Rong Yim,
Iain Bee Huat Tan,
Adaikalavan Ramasamy,
Hao Fan,
Ramanuj DasGupta
iScience
30 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
Joo-Leng Low,
Dawn Pingxi Lau,
Xiaoqian Zhang,
Xue-Lin Kwang,
Neha Rohatgi,
Jane Vin Chan,
Fui-Teen Chong,
Stephen Qi Rong Wong,
Hui-Sun Leong,
Matan Thangavelu Thangavelu,
Shivaji Rikka,
Anders Martin Jacobsen Skanderup,
Daniel Shao Weng Tan,
Giridharan Periyasamy,
Judice Lie Yong Koh,
N Gopalakrishna Iyer,
Ramanuj DasGupta
EBioMedicine
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