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5 Mar 2022
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Experimental Drug Development Centre
Application of High Throughput Technologies in the Development of Acute Myeloid Leukemia Therapy: Challenges and Progress
Wei Xiang,
Yi Hui Lam,
Giridharan Periyasamy,
Charles Chuah
International Journal of Molecular Sciences
18 Jan 2022
BMRC
Institute of Molecular and Cell Biology
Genome-wide screens identify specific drivers of mutant hTERT promoters
Raghuvaran Shanmugam,
Mert Burak Ozturk,
Joo-Leng Low,
Semih Can AKINCILAR,
Joelle Yi Heng Chua,
Matan Thangavelu Thangavelu,
Giridharan Periyasamy,
Ramanuj DasGupta,
Vinay Tergaonkar
Proceedings of the National Academy of Sciences
30 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
Joo-Leng Low,
Dawn Pingxi Lau,
Xiaoqian Zhang,
Xue-Lin Kwang,
Neha Rohatgi,
Jane Vin Chan,
Fui-Teen Chong,
Stephen Qi Rong Wong,
Hui-Sun Leong,
Matan Thangavelu Thangavelu,
Shivaji Rikka,
Anders Martin Jacobsen Skanderup,
Daniel Shao Weng Tan,
Giridharan Periyasamy,
Judice Lie Yong Koh,
N Gopalakrishna Iyer,
Ramanuj DasGupta
EBioMedicine
29 Apr 2020
BMRC
Bioinformatics Institute
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation
Li Ren Kong,
Richard Weijie Ong,
Tua Zea Tan,
Nur Afiqah Binte Mohamed Salleh,
Matan Thangavelu,
Jane Vin Chan,
Lie Yong Judice Koh,
Giridharan Periyasamy,
Jieying Amelia Lau,
Thi Bich Uyen Le,
Lingzhi Wang,
Miyoung Lee,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Chwee Ming Lim,
Wee Joo Chng,
David P. Lane,
Ashok Venkitaraman,
Huynh The Hung,
Chit Fang Cheok,
Boon Cher Goh
Nature Communications
1 Dec 2019
BMRC
Bioinformatics Institute
New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation
Justin L. Tan,
Feng Li,
Joanna Z. Yeo,
Kol Jia Yong,
Mahmoud A. Bassal,
Guo Hao Ng,
May Yin Lee,
Chung Yan Leong,
Hong Kee Tan,
Chan-shuo Wu,
Bee Hui Liu,
Tim H. Chan,
Zi Hui Tan,
Yun Shen Chan,
Siyu Wang,
Zhi Han Lim,
Tan Boon Toh,
Lissa Hooi,
Kia Ngee Low,
Siming Ma,
Nikki R. Kong,
Alicia J. Stein,
Yue Wu,
Matan T. Thangavelu,
Atsushi Suzuki,
Giridharan Periyasamy,
John M. Asara,
Yock Young Dan,
Glenn K. Bonney,
Edward K. Chow,
Guo-Dong Lu,
Huck Hui Ng,
Yoganathan Kanagasundaram,
Siew Bee Ng,
Wai Leong Tam,
Daniel G. Tenen,
Li Chai
Gastroenterology
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