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10 Jun 2024
BMRC
Institute of Molecular and Cell Biology
Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
LeLe Wu,
Zheng Zhao,
Yong Jae Shin,
Yiyun Yin,
Anandhkumar Raju,
Thamil Selvan Vaiyapuri,
Khaireen Idzham,
Miseol Son,
Yeri Lee,
Jason K. Sa,
Joelle Yi Heng Chua,
Bilal Unal,
You Zhai,
Wenhua Fan,
Lijie Huang,
Huimin Hu,
Jayantha Gunaratne,
Do-Hyun Nam,
Tao Jiang,
Vinay Tergaonkar
Nature Cell Biology
14 Jun 2022
BMRC
Institute of Molecular and Cell Biology
Identification of mechanism of cancer-cell-specific reactivation of hTERT offers therapeutic opportunities for blocking telomerase specifically in human colorectal cancer
Semih Can Akıncılar,
Joelle Yi Heng Chua,
Qin Feng NG,
Claire Hian Tzer Chan,
Zahra Eslami-S,
Kaijing Chen,
Joo-Leng Low,
Surendar Arumugam,
Luay Aswad,
Clarinda Chua,
Iain Beehuat Tan,
Ramanuj DasGupta,
Melissa Jane Fullwood,
Vinay Tergaonkar
Nucleic Acids Research
18 Jan 2022
BMRC
Institute of Molecular and Cell Biology
Genome-wide screens identify specific drivers of mutant hTERT promoters
Raghuvaran Shanmugam,
Mert Burak Ozturk,
Joo-Leng Low,
Semih Can AKINCILAR,
Joelle Yi Heng Chua,
Matan Thangavelu Thangavelu,
Giridharan Periyasamy,
Ramanuj DasGupta,
Vinay Tergaonkar
Proceedings of the National Academy of Sciences
25 Nov 2020
BMRC
Institute of Molecular and Cell Biology
NAIL: an evolutionarily conserved lncRNA essential for licensing coordinated activation of p38 and NFκB in colitis
Semih Can AKINCILAR,
LeLe Wu,
Qin Feng NG,
Joelle Yi Heng Chua,
Bilal Unal,
Taichi Noda,
Wei Hong Jeff Chor,
Masahito Ikawa,
Vinay Tergaonkar
Gut
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