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30 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
Joo-Leng Low,
Dawn Pingxi Lau,
Xiaoqian Zhang,
Xue-Lin Kwang,
Neha Rohatgi,
Jane Vin Chan,
Fui-Teen Chong,
Stephen Qi Rong Wong,
Hui-Sun Leong,
Matan Thangavelu Thangavelu,
Shivaji Rikka,
Anders Martin Jacobsen Skanderup,
Daniel Shao Weng Tan,
Giridharan Periyasamy,
Judice Lie Yong Koh,
N Gopalakrishna Iyer,
Ramanuj DasGupta
EBioMedicine
29 Apr 2020
BMRC
Bioinformatics Institute
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation
Li Ren Kong,
Richard Weijie Ong,
Tua Zea Tan,
Nur Afiqah Binte Mohamed Salleh,
Matan Thangavelu,
Jane Vin Chan,
Lie Yong Judice Koh,
Giridharan Periyasamy,
Jieying Amelia Lau,
Thi Bich Uyen Le,
Lingzhi Wang,
Miyoung Lee,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Chwee Ming Lim,
Wee Joo Chng,
David P. Lane,
Ashok Venkitaraman,
Huynh The Hung,
Chit Fang Cheok,
Boon Cher Goh
Nature Communications
1 Dec 2017
BMRC
p53 Laboratory
Role of the N-terminal lid in regulating the interaction of phosphorylated MDMX with p53
Jane Vin Chan,
Dawn Xin Ping Koh,
Yun Liu,
Thomas L. Joseph,
David P. Lane,
Chandra S. Verma,
Yaw Sing Tan
Oncotarget
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