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Publication date Communities Collections Article title Author(s) Journal/Conference
17 Jun 2024 BMRC Institute of Molecular and Cell Biology Iron-(Fe3+)-Dependent Reactivation of Telomerase Drives Colorectal Cancers (Pending publish) Raghuvaran Shanmugam, Prativa Majee, Wei Shi, Mert B. Ozturk, Thamil S. Vaiyapuri, Khaireen Idzham, Anandhkumar Raju, Seung H. Shin, Kerem Fidan, Joo-Leng Low, Joelle Y.H. Chua, Yap C. Kong, Ong Y. Qi, Emile Tan, Aik Y. Chok, Isaac Seow-En, Ian Wee, Dominique C. Macalinao, Dawn Q. Chong, Hong Y. Chang, Fiona Lee, Wei Q. Leow, Maki Murata-Hori, Zhang Xiaoqian, Chia Shumei, Chris S.H. Tan, Ramanuj DasGupta, Iain B. Tan, Vinay Tergaonkar Cancer Discovery
14 Jun 2022 BMRC Institute of Molecular and Cell Biology Identification of mechanism of cancer-cell-specific reactivation of hTERT offers therapeutic opportunities for blocking telomerase specifically in human colorectal cancer Semih Can Akıncılar, Joelle Yi Heng Chua, Qin Feng NG, Claire Hian Tzer Chan, Zahra Eslami-S, Kaijing Chen, Joo-Leng Low, Surendar Arumugam, Luay Aswad, Clarinda Chua, Iain Beehuat Tan, Ramanuj DasGupta, Melissa Jane Fullwood, Vinay Tergaonkar Nucleic Acids Research
18 Jan 2022 BMRC Institute of Molecular and Cell Biology Genome-wide screens identify specific drivers of mutant hTERT promoters Raghuvaran Shanmugam, Mert Burak Ozturk, Joo-Leng Low, Semih Can AKINCILAR, Joelle Yi Heng Chua, Matan Thangavelu Thangavelu, Giridharan Periyasamy, Ramanuj DasGupta, Vinay Tergaonkar Proceedings of the National Academy of Sciences
15 May 2021 BMRC Institute of Molecular and Cell Biology Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction Joo-Leng Low, Weina Du, Tenzin Gocha, Gokce Oguz, Xiaoqian Zhang, Ming Wei Chen, Srdan Masirevic, Daniel Guo Rong Yim, Iain Bee Huat Tan, Adaikalavan Ramasamy, Hao Fan, Ramanuj DasGupta iScience
30 Jan 2021 BMRC Institute of Molecular and Cell Biology A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC) Joo-Leng Low, Dawn Pingxi Lau, Xiaoqian Zhang, Xue-Lin Kwang, Neha Rohatgi, Jane Vin Chan, Fui-Teen Chong, Stephen Qi Rong Wong, Hui-Sun Leong, Matan Thangavelu Thangavelu, Shivaji Rikka, Anders Martin Jacobsen Skanderup, Daniel Shao Weng Tan, Giridharan Periyasamy, Judice Lie Yong Koh, N Gopalakrishna Iyer, Ramanuj DasGupta EBioMedicine