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25 Apr 2026
BMRC
Bioinformatics Institute
Spatial predictors of response to chemo-immunotherapy in microsatellite stable metastatic colorectal cancer
(Pending publish)
Joan Choo,
Joseph J. Zhao,
Mai Chan Lau,
Alessandra Raimondi,
Willa Wen-You Yim,
Sruthi Ranganathan,
Kexin Zhu,
Crystal Tze Ying Tan,
Hui Xian Chin,
Chong Boon Teo,
Khi Yung Fong,
Ryan Yong Kiat Tay,
Jia-Ying Joey Lee,
Lit-Hsin Loo,
Paolo Manca,
Federica Morano,
Michele Prisciandaro,
Giovanni Randon,
Camilla Damonte,
Elisa Micarelli,
Guido Leoni,
Elisa Scarselli,
Sara Lonardi,
Chiara Cremolini,
Federica Marmorino,
Jeffrey Chun Tatt Lim,
Zhen Wei Neo,
Felicia Wee,
Li Yen Chong,
Craig Ryan Joseph,
Akhila Balachander,
Diana GS Lim,
You Yi Hwang,
Laurent Renia,
Subhra Kumar Biswas,
David Tan,
Joe P. S. Yeong,
Raghav Sundar,
Filippo Pietrantonio
Nature Communications
18 Mar 2026
BMRC
Bioinformatics Institute
Early‐Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites
(Pending publish)
Nobuhiro Nakazawa,
Satoko Ugai,
Atsushi Kondo,
Kosuke Matsuda,
Shu Kato,
Genki Usui,
Shiori Tanaka,
Hwa‐Young Lee,
Xinyuan Zhang,
Hideo Miyagawa,
Mai Chan Lau,
Hiroshi Saeki,
Yukihide Kanemitsu,
Andrew T. Chan,
Shuji Ogino,
Minkyo Song,
Juha P. Väyrynen,
Tomotaka Ugai
Cancer Science
25 Jul 2025
BMRC
Singapore Immunology Network
The transcription complex p52–ETS1 is essential for germinal center formation
(Pending publish)
Dhakshayini Morgan,
Biyan Zhang,
Kerem Fidan,
Wenfai Pan,
Thamil Selvan Vaiyapuri,
Anandhkumar Raju,
Dorcas Hei,
Ting Yi See,
Ita Novita Sari,
Jun Wei Chan,
Prativa Majee,
Akhila Balachander,
Jiabo Yu,
Ada Hang-Heng Wong,
Michelle Meng Huang Mok,
Shi Hui Foo,
Wei Lin Tang,
Nicholas Ang,
Ivan Tan,
Yan Fen Peng,
Patrick Jaynes,
Shengli Xu,
Gourisankar Ghosh,
Shandy Shahabi,
Anand D. Jeyasekharan,
Masahito Ikawa,
Yongliang Zhang,
Shanshan Wu Howland,
Mai Chan Lau,
Vivien Ya-Fan Wang,
Kong-Peng Lam,
Vinay Tergaonkar
Nature Immunology
18 Feb 2025
BMRC
Bioinformatics Institute
Tumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment
Mai Chan Lau
PLOS Computational Biology
18 Feb 2025
BMRC
Bioinformatics Institute
Tumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment
Mai Chan Lau,
Jennifer Borowsky,
Juha P. Väyrynen,
Koichiro Haruki,
Melissa Zhao,
Andressa Dias Costa,
Simeng Gu,
Annacarolina da Silva,
Tomotaka Ugai,
Kota Arima,
Minh N. Nguyen,
Yasutoshi Takashima,
Joe Yeong,
David Tai,
Tsuyoshi Hamada,
Jochen K. Lennerz,
Charles S. Fuchs,
Catherine J. Wu,
Jeffrey A. Meyerhardt,
Shuji Ogino,
Jonathan A. Nowak
PLOS Computational Biology
22 Mar 2024
BMRC
Bioinformatics Institute
Spatial omics techniques and data analysis for cancer immunotherapy applications
Yue Zhang,
Ren Yuan Lee,
Chin Wee Tan,
Xue Guo,
Willa W-Y Yim,
Jeffrey CT Lim,
Felicia YT Wee,
WU Yang,
Malvika Kharbanda,
Jia-Ying J Lee,
Nye Thane Ngo,
Wei Qiang Leow,
Lit-Hsin Loo,
Tony KH Lim,
Radoslaw M Sobota,
Mai Chan Lau,
Melissa J Davis,
Joe Yeong
Current Opinion in Biotechnology
24 Nov 2023
BMRC
Genome Institute of Singapore
Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies
Jing Han Hong,
Chern Han Yong,
Hong Lee Heng,
Jason Yongsheng Chan,
Mai Chan Lau,
Jianfeng Chen,
Jing Yi Lee,
Abner Herbert Lim,
Zhimei Li,
Peiyong Guan,
Pek Lim Chu,
Arnoud Boot,
Sheng Rong Ng,
Xiaosai Yao,
Felicia Yu Ting Wee,
Jeffrey Chun Tatt Lim,
Wei Liu,
Peili Wang,
Rong Xiao,
Xian Zeng,
Yichen Sun,
Joanna Koh,
Xiu Yi Kwek,
Cedric Chuan Young Ng,
Poramate Klanrit,
Yaojun Zhang,
Jiaming Lai,
David Wai Meng Tai,
Chawalit Pairojkul,
Simona Dima,
Irinel Popescu,
Sen-Yung Hsieh,
Ming-Chin Yu,
Joe Yeong,
Sarinya Kongpetch,
Apinya Jusakul,
Watcharin Loilome,
Patrick Tan,
Jing Tan,
Bin Tean Teh
Gut
16 Aug 2023
BMRC
Bioinformatics Institute
Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma
Neslihan Arife Kaya,
David Tai,
Xinru Lim,
Jia Qi Lim,
Mai Chan Lau,
Denise Goh,
Cheryl Zi Jin Phua,
Felicia Yu Ting Wee,
Craig Ryan Joseph,
Jeffrey Chun Tatt Lim,
Zhen Wei Neo,
Jiangfeng Ye,
Lawrence Cheung,
Joycelyn Lee,
Kelvin S H Loke,
Apoorva Gogna,
Fei Yao,
May Yin Lee,
Timothy Wai Ho Shuen,
Han Chong Toh,
Axel Hilmer,
Yun Shen Chan,
Tony Kiat-Hon Lim,
Wai Leong Tam,
Su Pin Choo,
Joe Yeong,
Weiwei Zhai
Journal for ImmunoTherapy of Cancer
1 May 2023
BMRC
Institute of Molecular and Cell Biology
The promise and challenge of spatial omics in dissecting tumour microenvironment and the role of AI
Ren Yuan Lee,
Chan Way Ng,
Menaka Priyadharsani Rajapakse,
Nicholas Ang,
Joe Poh Sheng Yeong,
Mai Chan Lau
Frontiers in Oncology
15 Apr 2023
BMRC
Institute of Molecular and Cell Biology
Application of Artificial Intelligence to In Vitro Tumor Modeling and Characterization of the Tumor Microenvironment
Ren Yuan Lee,
Yang Wu,
Denise Goh,
Verlyn Tan,
Chan Way Ng,
Jeffrey Chun Tatt Lim,
Mai Chan Lau,
Joe Poh Sheng Yeong
Advanced Healthcare Materials
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