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30 Jul 2025
BMRC
Genome Institute of Singapore
Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning
Mauricio Perez,
Michiko Kimoto,
Priscilla Rajakumar,
Chayaporn Suphavilai,
Rafael Peres da Silva,
Hui Pen Tan,
Nicholas Ting Xun Ong,
Hannah Nicholas,
Ichiro Hirao,
Wei Leong Chew,
Niranjan Nagarajan
Nature Communications
12 Jan 2023
BMRC
Bioinformatics Institute
Success probability of high-affinity DNA aptamer generation by genetic alphabet expansion
Michiko Kimoto,
Hui Pen Tan,
Yaw Sing Tan,
Nur Afiqah Binte Mohd Mislan,
Ichiro Hirao
Philosophical Transactions of the Royal Society B: Biological Sciences
25 Jun 2021
BMRC
Institute of Bioengineering and Bioimaging
High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification
Ken-ichiro Matsunaga,
Michiko Kimoto,
Vanessa Weixun Lim,
Hui Pen Tan,
Yu Qian Wong,
William Sun,
Shawn Vasoo,
Yee Sin Leo,
Ichiro Hirao
Nucleic Acids Research
6 Nov 2020
BMRC
Institute of Bioengineering and Nanotechnology
Cognate base-pair selectivity of hydrophobic unnatural bases in DNA ligation by T4 DNA ligase
Michiko Kimoto,
Si Hui Gabriella Soh,
Hui Pen Tan,
Itaru Okamoto,
Ichiro Hirao
Biopolymers
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