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23 Apr 2026
Others
Experimental Drug Development Centre
Illuminating Clinical TEAD Inhibitors Through Structural Biology
(Pending publish)
CongBao Kang,
Weijun Xu,
Haiwei Song,
Wanjin Hong
Journal of Medicinal Chemistry
26 Mar 2026
Others
Experimental Drug Development Centre
In Silico‐Enabled Discovery and Development of Potent and Selective CDK11 Inhibitors
(Pending publish)
Frankie S. Mak,
Fui Mee Ng,
Padmanabhan Anbazhagan,
Vikas Madan,
Qian Wen Tan,
Yiyang See,
Diane Lim,
Frances Karla Kusuma,
Hannah Toh,
Juliana Mohammad,
Haiyan Yang,
Sandra Sim,
Li Hong Tan,
Eileen Tay,
Ronald Toh Kuan Hai,
Perlyn Zekui Kwek,
Mei Yee Wong,
Deepika Raman,
Qi An Ang,
Vithya Manoharan,
Susmitha Vuddagiri,
Monique Danielle Dawson,
Alison Tan,
Joma Kanikadu Joy,
Bong Hwa Gan,
Choon Bing Low,
Haoying Xu,
Siew Pheng Lim,
Hannes Hentze,
Joseph Cherian,
Chong Teik Tan,
Jackie Ang,
Kantharaj Ethirajulu,
Klement Foo,
Inderjeet Singh,
Weijun Xu
ChemMedChem
14 Mar 2026
Others
Experimental Drug Development Centre
An inactive Zika NS2B-NS3pro protease construct for investigating allosteric inhibitors
Khac Huy Ngo,
Simon Lattmann,
Paulina Duhita Anindita,
Chong Wai Liew,
Reuben S. Harris,
Dahai Luo,
CongBao Kang
Journal of Structural Biology
26 Feb 2026
Others
Experimental Drug Development Centre
Discovery of Pan-TEAD Inhibitors That Disrupt YAP-TEAD Interaction as a Potential Therapy for Gastric Cancers and Mutant KRAS and EGFR Lung Cancers
(Pending publish)
Ramesh Kumar,
Joanne Thian,
Joel D. W. Toh,
Noorul Farzana,
Jialin Sun,
CongBao Kang,
Suet Mei Crystal Low,
Sheena Wee,
Zijie Lim,
Jayantha Gunaratne,
Hui Mun Loh,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Sayan Chakraborty,
Wanjin Hong
ACS Medicinal Chemistry Letters
16 Jul 2025
Others
Experimental Drug Development Centre
Entry Inhibitors of SARS-CoV-2 Targeting the Transmembrane Domain of the Spike Protein
Kristin V. Lyles,
Shannon Stone,
Priti Singh,
Lila D. Patterson,
Janhavi Natekar,
Heather Pathak,
Rohit K. Varshnaya,
Amany Elsharkawy,
Dongning Liu,
Shubham Bansal,
Oluwafoyinsola O. Faniyi,
Sijia Tang,
Xiaoxiao Yang,
Nagaraju Mulpuri,
Donald Hamelberg,
CongBao Kang,
Binghe Wang,
Mukesh Kumar,
Ming Luo
Viruses
25 Apr 2025
Others
Experimental Drug Development Centre
Structure-based discovery of novel non-covalent small molecule inhibitors of USP30
Padmanabhan Anbazhagan,
Jothi Anantharajan,
Justina Fulwood,
Choon Heng Low,
Nithya Baburajendran,
Klement Foo,
Weijun Xu
Journal of Computer-Aided Molecular Design
10 Apr 2025
Others
Experimental Drug Development Centre
Therapeutic potential of targeting ubiquitin-specific proteases in colorectal cancer
Chern Ein Oon,
Padmanabhan Anbazhagan,
Chong Teik Tan
Drug Discovery Today
23 May 2024
Others
Experimental Drug Development Centre
A high-throughput cell-based screening method for Zika virus protease inhibitor discovery
Paulina Duhita Anindita,
Yuka Otsuka,
Simon Lattmann,
Khac Huy Ngo,
Chong Wai Liew,
CongBao Kang,
Reuben S. Harris,
Louis Scampavia,
Timothy P. Spicer,
Dahai Luo
SLAS Discovery
14 Nov 2020
BMRC
Singapore Institute of Food and Biotechnology Innovation
In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation
Chung Yan Leong,
Veronica Ng,
Yoganathan Kanagasundaram,
Hao Fan,
Siew Bee Ng,
Kishore Reddy Venkata Thappeta,
Li Na Zhao,
Choy Eng Nge,
Sharon Crasta
International Journal of Molecular Sciences
28 Feb 2020
BMRC
Bioinformatics Institute
Viruses go modular
Ariel Shepley-McTaggart,
Hao Fan,
Marius Sudol,
Ronald N. Harty
Journal of Biological Chemistry
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