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24 Jan 2025
Others
Experimental Drug Development Centre
Leveraging Structural and Computational Biology for Molecular Glue Discovery
CongBao Kang,
Weijun Xu
Journal of Medicinal Chemistry
24 Oct 2024
Others
Experimental Drug Development Centre
Current Status of Computational Approaches for Small Molecule Drug Discovery
Weijun Xu
Journal of Medicinal Chemistry
4 Jul 2024
Others
Experimental Drug Development Centre
Ultra-large scale virtual screening identifies a small molecule inhibitor of the Wnt transporter Wntless
Jia Yu,
Pei-Ju Liao,
Thomas H. Keller,
Joseph Cherian,
David M. Virshup,
Weijun Xu
iScience
25 Mar 2020
BMRC
Bioinformatics Institute
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma
Nur Afiqah Binte Mohamed Salleh,
Richard Weijie Ong,
Li Ren Kong,
Tuan Zea Tan,
Nicholas L. Syn,
Robby Miguel Goh,
Chee Wai Fhu,
Daniel S W Tan,
Gopalakrishna Iyer,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Yaw Chyn Lim,
Ross Soo,
Jingshan Ho,
Yiqing Huang,
Joline S. J. Lim,
Benedict Junrong Yan,
Min En Nga,
Seng Gee Lim,
H. Philip Koeffler,
Soo Chin Lee,
Dennis Kappei,
Huyhn The Hung,
Boon Cher Goh
Nature Communications
3 Sep 2019
BMRC
Institute of Medical Biology
Membrane lipid binding molecules for the isolation of bona fide extracellular vesicle types and associated biomarkers in liquid biopsy
Ruenn Chai Lai,
Kok Hian Tan,
Sai Kiang Lim
Journal of Cancer Metastasis and Treatment
29 May 2019
BMRC
Bioinformatics Institute
Characterization of Hydration Properties in Structural Ensembles of Biomolecules
Mohan R. Pradhan,
Minh N. Nguyen,
Srinivasaraghavan Kannan,
Stephen J. Fox,
Chee Keong Kwoh,
David P. Lane,
Chandra S. Verma
Journal of Chemical Information and Modeling
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