Search results

Publication date Communities Collections Article title Author(s)
25 Mar 2020 BMRC Bioinformatics Institute A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Li Ren Kong, Tuan Zea Tan, Nicholas L. Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel S W Tan, Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S. Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline S. J. Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H. Philip Koeffler, Soo Chin Lee, Dennis Kappei, Huyhn The Hung, Boon Cher Goh
1 Feb 2020 BMRC Institute of Molecular and Cell Biology AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells Maria L. Lotsberg, Katarzyna Wnuk-Lipinska, Stéphane Terry, Tuan Zea Tan, Ning Lu, Laura Trachsel-Moncho, Gro V. Røsland, Muntequa I. Siraji, Monica Hellesøy, Austin Rayford, Kirstine Jacobsen, Henrik J. Ditzel, Olav K. Vintermyr, Trever G. Bivona, John Minna, Rolf A. Brekken, Bruce Baguley, David Micklem, Lars A. Akslen, Gro Gausdal, Anne Simonsen, Jean Paul Thiery, Salem Chouaib, James B. Lorens, Agnete Svendsen Tenfjord Engelsen
25 Sep 2019 BMRC Bioinformatics Institute c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression Wen Jing Sim, Prasanna Vasudevan Iyengar, Dilraj Lama, Sara Kit Leng Lui, Hsien Chun Ng, Lior Haviv-Shapira, Eytan Domany, Dennis Kappei, Tuan Zea Tan, Azad Saie, Patrick William Jaynes, Chandra Shekhar Verma, Hong Koo Ha, Camelia Radulescu, Peter ten Dijke, Pieter Johan Adam Eichhorn, Jean Paul Thiery, Alan Prem Kumar, Mathieu Rouanne
1 Jun 2019 BMRC Institute of Molecular and Cell Biology Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC Gro V. Røsland, Sissel E. Dyrstad, Deusdedit Tusubira, Reham Helwa, Tuan Zea Tan, Maria L. Lotsberg, Ina K. N. Pettersen, Anna Berg, Charlotte Kindt, Fredrik Hoel, Kirstine Jacobsen, Ari J. Arason, Agnete S. T. Engelsen, Henrik J. Ditzel, Per E. Lønning, Camilla Krakstad, Jean P. Thiery, James B. Lorens, Stian Knappskog, Karl J. Tronstad
11 Dec 2018 BMRC Institute of Molecular and Cell Biology The FZD 7‐TWIST 1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma Clare Scott, Ruby Yun‐Ju Huang, Ming Tan, Mohammad Asad, Valerie Heong, Meng Kang Wong, Tuan Zea Tan, Jieru Ye, Kuee Theng Kuay, Jean Paul Thiery
15 Jun 2018 BMRC Institute of Molecular and Cell Biology The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancer Jane Antony, Elisa Zanini, Zoe Kelly, Tuan Zea Tan, Evdoxia Karali, Mohammad Alomary, Youngrock Jung, Katherine Nixon, Paula Cunnea, Christina Fotopoulou, Andrew Paterson, Sushmita Roy‐Nawathe, Gordon B Mills, Ruby Yun‐Ju Huang, Jean Paul Thiery, Hani Gabra, Chiara Recchi
7 Mar 2018 BMRC Institute of Molecular and Cell Biology A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase Jianbiao Zhou, Sabrina Hui-Min Toh, Zit-Liang Chan, Jessie Yiying Quah, Jing-Yuan Chooi, Tuan Zea Tan, Phyllis S. Y. Chong, Qi Zeng, Wee-Joo Chng
27 May 2015 BMRC Institute of Molecular and Cell Biology Functional relevance of a six mesenchymal gene signature in epithelial-mesenchymal transition (EMT) reversal by the triple angiokinase inhibitor, nintedanib (BIBF1120) Ruby Yun-Ju Huang, Kuee Theng Kuay, Tuan Zea Tan, Aloysius Hsien Chun Ng, Jieru Ye, Vin Yee Chung, Mohammad Asad, Hei Mui Tang, Jean Paul Thiery
6 May 2015 BMRC Institute of Molecular and Cell Biology Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy Prashant Kumar, Sayantani Nandi, Bee Luan Khoo, Soo Chin Lee, Tuan Zea Tan, Majid Ebrahimi Warkiani, Samuel GW Ow, Chwee Teck Lim, Jean Paul Thiery
15 Apr 2015 BMRC Institute of Molecular and Cell Biology Highly sensitive and specific novel biomarkers for the diagnosis of transitional bladder carcinoma Prashant Kumar, Sayantani Nandi, Tuan Zea Tan, Siok Ghee Ler, Kee Seng Chia, Wei-Yen Lim, Zentia Bütow, Dimitrios Vordos, Alexandre De laTaille, Muthafar Al-Haddawi, Manfred Raida, Burkhard Beyer, Estelle Ricci, Marc Colombel, Tsung Wen Chong, Edmund Chiong, Ross Soo, Mi Kyoung Park, Hong Koo Ha, Jayantha Gunaratne, Jean Paul Thiery
7 Sep 2014 BMRC Institute of Molecular and Cell Biology A central role for TRPS1 in the control of cell cycle and cancer development LeLe Wu, Yuzhi Wang, Yan Liu, Shiyi Yu, Hao Xie, Xingjuan Shi, Sheng Qin, Fei Ma, Tuan Zea Tan, Jean Paul Thiery, Liming Chen
7 Aug 2014 BMRC Institute of Molecular and Cell Biology Disruption of Runx1 and Runx3 Leads to Bone Marrow Failure and Leukemia Predisposition due to Transcriptional and DNA Repair Defects Chelsia Qiuxia Wang, Vaidehi Krishnan, Lavina Sierra Tay, Desmond Wai Loon Chin, Cai Ping Koh, Jing Yuan Chooi, Giselle Sek Suan Nah, Linsen Du, Bindya Jacob, Namiko Yamashita, Soak Kuan Lai, Tuan Zea Tan, Seiichi Mori, Ichiro Tanuichi, Vinay Tergaonkar, Yoshiaki Ito, Motomi Osato
1 Aug 2014 BMRC Institute of Molecular and Cell Biology DEAD-box helicase DP103 defines metastatic potential of human breast cancers Eun Myoung Shin, Hui Sin Hay, Moon Hee Lee, Jen Nee Goh, Tuan Zea Tan, Yin Ping Sen, See Wee Lim, Einas M. Yousef, Hooi Tin Ong, Aye Aye Thike, Xiangjun Kong, Zhengsheng Wu, Earnest Mendoz, Wei Sun, Manuel Salto-Tellez, Chwee Teck Lim, Peter E. Lobie, Yoon Pin Lim, Celestial T. Yap, Qi Zeng, Gautam Sethi, Martin B. Lee, Patrick Tan, Boon Cher Goh, Lance D. Miller, Jean Paul Thiery, Tao Zhu, Louis Gaboury, Puay Hoon Tan, Kam Man Hui, George Wai-Cheong Yip, Shigeki Miyamoto, Alan Prem Kumar, Vinay Tergaonkar
6 Jul 2014 BMRC Institute of Medical Biology Lgr5 Marks Stem/Progenitor Cells in Ovary and Tubal Epithelia Annie Ng, Shawna Tan, Gurmit Singh, Pamela Rizk, Yada Swathi, Tuan Zea Tan, Ruby Yun-Ju Huang, Marc Leushacke, Nick Barker
27 Mar 2014 BMRC Institute of Molecular and Cell Biology SPHK1 regulates proliferation and survival responses in triple-negative breast cancer Sheryl S.L. Tan, Baohua Huang, Lingkai Wong, Arpita Datta, Ser Yue Loo, Tuan Zea Tan, Soo-Chin Lee, Jean Paul Thiery, Yaw Chyn Lim, Wei Peng Yong, Yulin Lam, Alan Prem Kumar, Celestial T. Yap