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5 May 2022
BMRC
Institute of Molecular and Cell Biology
Phosphoproteomics Unravel HBV Triggered Rewiring of Host Phosphosignaling Events
Zijie Lim,
Nur Khairiah Binte Mohd-Ismail,
Evelyn Png,
Ching Wooen Sze,
Qifeng Lin,
Wanjin Hong,
Seng Gee Lim,
Yee-Joo Tan,
Jayantha Gunaratne
International Journal of Molecular Sciences
18 Mar 2021
BMRC
Institute of Molecular and Cell Biology
Analysis and validation of human targets and treatments using a hepatocellular carcinoma‐immune humanized mouse model
Yue Zhao,
Jiaxu Wang,
Wai Nam Liu,
Shin Yie Fong,
Timothy Wai Ho Shuen,
Min Liu,
Sarah Harden,
Sue Yee Tan,
Jia Ying Cheng,
Wilson Wei Sheng Tan,
Jerry Kok Yen Chan,
Cheng Ean Chee,
Guan Huei Lee,
Han Chong Toh,
Seng Gee Lim,
Yue Wan,
Qingfeng Chen
Hepatology
11 Sep 2020
BMRC
Institute of Molecular and Cell Biology
CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice
Zhisheng Her,
Joel Heng Loong Tan,
Yee-Siang Lim,
Sue Yee Tan,
Xue Ying Chan,
Wilson Wei Sheng Tan,
Min Liu,
Kylie Su Mei Yong,
Fritz Lai,
Erica Ceccarello,
Zhiqiang Zheng,
Yong Fan,
Kenneth Tou En Chang,
Lei Sun,
Shih Chieh Chang,
Chih-Liang Chin,
Guan Huei Lee,
Yock Young Dan,
Yun-Shen Chan,
Seng Gee Lim,
Jerry Kok Yen Chan,
K. George Chandy,
Qingfeng Chen
Frontiers in Immunology
25 Mar 2020
BMRC
Bioinformatics Institute
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma
Nur Afiqah Binte Mohamed Salleh,
Richard Weijie Ong,
Li Ren Kong,
Tuan Zea Tan,
Nicholas L. Syn,
Robby Miguel Goh,
Chee Wai Fhu,
Daniel S W Tan,
Gopalakrishna Iyer,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Yaw Chyn Lim,
Ross Soo,
Jingshan Ho,
Yiqing Huang,
Joline S. J. Lim,
Benedict Junrong Yan,
Min En Nga,
Seng Gee Lim,
H. Philip Koeffler,
Soo Chin Lee,
Dennis Kappei,
Huyhn The Hung,
Boon Cher Goh
Nature Communications
30 Mar 2018
BMRC
Institute of Molecular and Cell Biology
Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy
Seng Gee Lim,
Qingfeng Chen,
Yue Zhao,
Timothy Wai Ho Shuen,
Tan Boon Toh,
Xue Ying Chan,
Min Liu,
Sue Yee Tan,
Yong Fan,
Hechuan Yang,
Shridhar Ganpathi Lyer,
Glenn Kunnath Bonney,
Eva Loh,
Kenneth Tou En Chang,
Thiam Chye Tan,
Weiwei Zhai,
Jerry Kok Yen Chan,
Edward Kai-Hua Chow,
Cheng Ean Chee,
Guan Huei Lee,
Yock Young Dan,
Pierce Kah-Hoe Chow,
Han Chong Toh
Gut
27 Oct 2017
BMRC
Institute of Molecular and Cell Biology
Single-virion sequencing of lamivudine-treated HBV populations reveal population evolution dynamics and demographic history
Yuan O. Zhu,
Pauline P. K. Aw,
Paola Florez De Sessions,
Shuzhen Hong,
Lee Xian See,
Lewis Z. Hong,
Andreas Wilm,
Chen Hao Li,
Stephane Hue,
Seng Gee Lim,
Niranjan Nagarajan,
William F. Burkholder,
Martin Hibberd
BMC Genomics
13 Nov 2015
BMRC
Institute of Molecular and Cell Biology
Overexpression of Tyro3 and its implications on hepatocellular carcinoma progression
Yan Duan,
Winnie Wong,
Sonja Courtney Chua,
Hwee Lin Wee,
Seng Gee Lim,
Boon Tin Chua,
Han Kiat Ho
International Journal of Oncology
6 Jul 2015
BMRC
Institute of Molecular and Cell Biology
Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection
Kenneth T E Chang,
Kylie Su Mei Yong,
Choong Tat Keng,
Ching Wooen Sze,
Dahai Zheng,
Zhiqiang Zheng,
Shu Qi Tan,
Jessica Jie Ying Ong,
Sue Yee Tan,
Eva Loh,
Megha Haridas Upadya,
Chik Hong Kuick,
Hak Hotta,
Seng Gee Lim,
Thiam Chye Tan,
Wanjin Hong,
Jianzhu Chen,
Yee-Joo Tan,
Qingfeng Chen
Gut
29 Jun 2015
BMRC
Institute of Molecular and Cell Biology
A 2015 roadmap for the management of hepatitis C virus infections in Asia
Seng Gee Lim,
Yock Young Dan
The Korean Journal of Internal Medicine
1 Aug 2013
BMRC
Singapore Institute for Clinical Sciences
Mobilizing monocytes to cross-present circulating viral antigen in chronic infection
Adeline Chia,
Seng Gee Lim,
Carlo Ferrari,
Florent Ginhoux,
Antonio Bertoletti,
Muzlifah Haniffa,
Patrick T. Kennedy,
Zi Zong Ho,
Carolina Boni,
Amanda Shin,
Adam J. Gehring,
Nasirah Banu
Journal of Clinical Investigation
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