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23 Nov 2022
BMRC
Institute of Molecular and Cell Biology
Successful targeting of PD-1/PD-L1 with chimeric antigen receptor-natural killer cells and nivolumab in a humanized mouse cancer model
Wai Nam Liu,
Wing Yan So,
Sarah L. Harden,
Shin Yie Fong,
Melissa Xin Yu Wong,
Wilson Wei Sheng Tan,
Sue Yee Tan,
Jessica Kai Lin Ong,
Ravisankar Rajarethinam,
Min Liu,
Jia Ying Cheng,
Lisda Suteja,
Joe Poh Sheng Yeong,
N. Gopalakrishna Iyer,
Darren Wan-Teck Lim,
Qingfeng Chen
Science Advances
30 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
Joo-Leng Low,
Dawn Pingxi Lau,
Xiaoqian Zhang,
Xue-Lin Kwang,
Neha Rohatgi,
Jane Vin Chan,
Fui-Teen Chong,
Stephen Qi Rong Wong,
Hui-Sun Leong,
Matan Thangavelu Thangavelu,
Shivaji Rikka,
Anders Martin Jacobsen Skanderup,
Daniel Shao Weng Tan,
Giridharan Periyasamy,
Judice Lie Yong Koh,
N Gopalakrishna Iyer,
Ramanuj DasGupta
EBioMedicine
22 Apr 2020
BMRC
Institute of Molecular and Cell Biology
Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy
Wilson Wei Sheng Tan,
Sue Yee Tan,
Wai Nam Liu,
Shin Yie Fong,
Min Liu,
Jia Ying Cheng,
Sherlly Lim,
Lisda Suteja,
Edwin Kunxiang Huang,
Jerry Kok Yen Chan,
Narayanan Gopalakrishna Iyer,
Joe Poh Sheng Yeong,
Darren Wan-Teck Lim,
Qingfeng Chen
Cancers
25 Mar 2020
BMRC
Bioinformatics Institute
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma
Nur Afiqah Binte Mohamed Salleh,
Richard Weijie Ong,
Li Ren Kong,
Tuan Zea Tan,
Nicholas L. Syn,
Robby Miguel Goh,
Chee Wai Fhu,
Daniel S W Tan,
Gopalakrishna Iyer,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Yaw Chyn Lim,
Ross Soo,
Jingshan Ho,
Yiqing Huang,
Joline S. J. Lim,
Benedict Junrong Yan,
Min En Nga,
Seng Gee Lim,
H. Philip Koeffler,
Soo Chin Lee,
Dennis Kappei,
Huyhn The Hung,
Boon Cher Goh
Nature Communications
22 Aug 2019
BMRC
Institute of Medical Biology
Circulating extracellular vesicle-associated TGFβ3 modulates response to cytotoxic therapy in head and neck squamous cell carcinoma
André Luiz Vettore,
Dorival Mendes-Junior Rodrigues,
Soon Sim Tan,
Sai Kiang Lim,
Hui Sun Leong,
Matias Eliseo Melendez,
Cintia Regina Niederauer Ramos,
Luciano de Souza Viana,
Daniel S. W. Tan,
André Lopes Carvalho,
N. Gopalakrishna Iyer
Carcinogenesis
23 Apr 2019
BMRC
Institute of Medical Biology
A preliminary investigation of circulating extracellular vesicles and biomarker discovery associated with treatment response in head and neck squamous cell carcinoma
Dorival Mendes Rodrigues-Junior,
Soon Sim Tan,
Luciano de Souza Viana,
André Lopes Carvalho,
Sai Kiang Lim,
N Gopalakrishna Iyer,
André Luiz Vettore
BMC Cancer
19 Dec 2017
BMRC
Institute of Molecular and Cell Biology
GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers
Patrick J. Casey,
N. Gopalakrishna Iyer,
Suhail Ahmed Kabeer Rasheed,
Hui Sun Leong,
Manikandan Lakshmanan,
Anandhkumar Raju,
Dhivya Dadlani,
Fui-Teen Chong,
Nicholas B Shannon,
Ravisankar Rajarethinam,
Thakshayeni Skanthakumar,
Ern Yu Tan,
Jacqueline Siok Gek Hwang,
Kok Hing Lim,
Daniel Shao-Weng Tan,
Paolo Ceppi,
Mei Wang,
Vinay Tergaonkar
Oncogene
24 Feb 2015
BMRC
Institute of Molecular and Cell Biology
Paracrine Factors of Human Fetal MSCs Inhibit Liver Cancer Growth Through Reduced Activation of IGF-1R/PI3K/Akt Signaling
Kiat Hon Lim,
Jennifer P Newman,
Xin Yi Toh,
Berwini B Endaya,
Hui Sun Leong,
Narayanan Gopalakrishna Iyer,
Kam Man Hui,
Paula Y P Lam,
Jerry K Y Chan,
Massimiliano Gnecchi,
Hung Huynh,
Yulyana Yulyana,
Ivy A W Ho,
Kian Chuan Sia,
Alexander Y F Chung
Molecular Therapy
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