Search results

Publication date Communities Collections Article title Author(s) Journal/Conference
15 Feb 2022 BMRC Institute of Molecular and Cell Biology Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes Jia Tong Loh, Bin Zhang, Joey Kay Hui Teo, Ruenn Chai Lai, Andre Boon Hwa Choo, Kong-Peng Lam, Sai Kiang Lim Cytotherapy
3 Sep 2019 BMRC Institute of Medical Biology Membrane lipid binding molecules for the isolation of bona fide extracellular vesicle types and associated biomarkers in liquid biopsy Ruenn Chai Lai, Kok Hian Tan, Sai Kiang Lim Journal of Cancer Metastasis and Treatment
22 Aug 2019 BMRC Institute of Medical Biology Circulating extracellular vesicle-associated TGFβ3 modulates response to cytotoxic therapy in head and neck squamous cell carcinoma André Luiz Vettore, Dorival Mendes-Junior Rodrigues, Soon Sim Tan, Sai Kiang Lim, Hui Sun Leong, Matias Eliseo Melendez, Cintia Regina Niederauer Ramos, Luciano de Souza Viana, Daniel S. W. Tan, André Lopes Carvalho, N. Gopalakrishna Iyer Carcinogenesis
29 Apr 2019 BMRC Institute of Medical Biology Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications Kenneth W. Witwer, Bas W. M. van Balkom, Stefania Bruno, Andre Choo, Massimo Dominici, Mario Gimona, Andrew F. Hill, Dominique De Kleijn, Mickey Koh, Ruenn Chai Lai, S. Alex Mitsialis, Luis A. Ortiz, Eva Rohde, Takashi Asada, Wei Seong Toh, Daniel J. Weiss, Lei Zheng, Bernd Giebel, Sai Kiang Lim Journal of Extracellular Vesicles
23 Apr 2019 BMRC Institute of Medical Biology A preliminary investigation of circulating extracellular vesicles and biomarker discovery associated with treatment response in head and neck squamous cell carcinoma Dorival Mendes Rodrigues-Junior, Soon Sim Tan, Luciano de Souza Viana, André Lopes Carvalho, Sai Kiang Lim, N Gopalakrishna Iyer, André Luiz Vettore BMC Cancer
13 Dec 2017 BMRC Institute of Medical Biology Extracellular vesicles yield predictive pre-eclampsia biomarkers Kok Hian Tan, Soon Sim Tan, Mor Jack Ng, Wan Shi Tay, Wei Kian Sim, John Carson Allen, Sai Kiang Lim Journal of Extracellular Vesicles
31 Dec 2015 BMRC Institute of Medical Biology Applying extracellular vesicles based therapeutics in clinical trials Thomas Lener, Mario Gimona, Ludwig Aigner, Verena Börger, Edit Buzas, Giovanni Camussi, Nathalie Chaput, Devasis Chatterjee, Felipe A. Court, Hernando A. del Portillo, Lorraine O’Driscoll, Stefano Fais, Juan M. Falcón-Pérez, Ursula Felderhoff-Mueser, Lorenzo Fraile, Yong Song Gho, André Görgens, Ramesh C. Gupta, An Hendrix, Dirk M. Hermann, Andrew F. Hill, Fred Hochberg, Peter A. Horn, Dominique De Kleijn, Lambros Kordelas, Boris W. Kramer, Eva-Maria Krämer-Albers, Sandra Laner-Plamberger, Saara Laitinen, Tommaso Leonardi, Magdalena J. Lorenowicz, Sai Kiang Lim, Jan Lötvall, Casey A. Maguire, Antonio Marcilla, Irina Nazarenko, Takahiro Ochiya, Tushar Patel, Shona Pedersen, Gabriella Pocsfalvi, Stefano Pluchino, Peter Quesenberry, Ilona G. Reischl, Francisco J. Rivera, Ralf Sanzenbacher, Katharina Schallmoser, Ineke Slaper-Cortenbach, Dirk Strunk, Torsten Tonn, Pieter Vader, Bas W. M. van Balkom, Marca Wauben, Samir El Andaloussi, Coltilde Thery, Eva Rohde, Bernd Giebel Journal of Extracellular Vesicles
9 Mar 2015 BMRC Institute of Medical Biology Mesenchymal Stem Cell Exosomes Ruenn Chai Lai, Ronne Wee Yeh Yeo, Sai Kiang Lim Seminars in Cell & Developmental Biology
22 Oct 2014 BMRC Institute of Medical Biology Immunotherapeutic potential of extracellular vesicles Bin Zhang, Yijun Yin, Ruenn Chai Lai, Sai Kiang Lim Frontiers in Immunology
10 Feb 2014 BMRC Institute of Medical Biology Mesenchymal Stem Cells Secrete Immunologically Active Exosomes Bin Zhang, Yijun Yin, Ruenn Chai Lai, Soon Sim Tan, Andre Boon Hwa Choo, Sai Kiang Lim Stem Cells and Development
23 Dec 2013 BMRC Institute of Medical Biology Therapeutic MSC exosomes are derived from lipid raft microdomains in the plasma membrane Soon Sim Tan, Yijun Yin, Tricia Lee, Ruenn Chai Lai, Ronne Wee Yeh Yeo, Bin Zhang, Andre Choo, Sai Kiang Lim Journal of Extracellular Vesicles
12 Nov 2013 BMRC Institute of Medical Biology Mesenchymal stem cell exosome ameliorates reperfusion injury through proteomic complementation (Pending publish) Kok Hian Tan, Sai Kiang Lim, Ruenn Chai Lai, Ronne Wee Yeh Yeo Regenerative Medicine
8 Nov 2013 BMRC Institute of Medical Biology Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome (Pending publish) Ruenn Chai Lai, Soon Sim Tan, Bao Ju Teh, Siu Kwan Sze, Fatih Arslan, Dominique P. de Kleijn, Andre Choo, Sai Kiang Lim International Journal of Proteomics
8 Nov 2013 BMRC Institute of Medical Biology Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease (Pending publish) Ruenn Chai Lai, Tian Sheng Chen, Sai Kiang Lim Regenerative Medicine
5 May 2013 BMRC Institute of Medical Biology Measurement of Precursor miRNA in Exosomes from Human ESC-Derived Mesenchymal Stem Cells (Pending publish) Nobuyoshi Kosaka, Tian Sheng Chen, Sai Kiang Lim Methods in Molecular Biology
14 Jan 2013 BMRC Institute of Medical Biology Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury (Pending publish) Fatih Arslan, Ruenn Chai Lai, Mirjam B. Smeets, Lars Akeroyd, Andre Choo, Eissa N.E. Aguor, Leo Timmers, Harold V. van Rijen, Pieter A. Doevendans, Gerard Pasterkamp, Sai Kiang Lim, Dominique P. de Kleijn Stem Cell Research
27 Sep 2012 BMRC Institute of Medical Biology Mesenchymal Stem Cell Exosomes: The Future MSC-Based Therapy? (Pending publish) Newman Siu Kwan Sze, Andre Choo, Sai Kiang Lim, Soon Sim Tan, Bin Zhang, Yijun Yin, Ruenn Chai Lai, Ronne Wee Yeh Yeo, Lucas G. Chase, Mohan C. Vemuri Stem Cell Biology and Regenerative Medicine
14 Sep 2012 BMRC Institute of Medical Biology High Glucose Predisposes Gene Expression and ERK Phosphorylation to Apoptosis and Impaired Glucose-Stimulated Insulin Secretion via the Cytoskeleton (Pending publish) Ronne Wee Yeh Yeo, Kaiyuan Yang, GuoDong Li, Sai Kiang Lim, Kathrin Maedler PLoS ONE
25 Aug 2012 BMRC Institute of Medical Biology Exosomes for drug delivery — a novel application for the mesenchymal stem cell (Pending publish) Ruenn Chai Lai, Ronne Wee Yeh Yeo, Kok Hian Tan, Sai Kiang Lim Biotechnology Advances
7 Jul 2012 BMRC Institute of Medical Biology Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery (Pending publish) Ronne Wee Yeh Yeo, Ruenn Chai Lai, Bin Zhang, Soon Sim Tan, Yijun Yin, Bao Ju Teh, Sai Kiang Lim Advanced Drug Delivery Reviews
6 Apr 2012 BMRC Institute of Medical Biology Metabolic Adaptation to a Disruption in Oxygen Supply during Myocardial Ischemia and Reperfusion Is Underpinned by Temporal and Quantitative Changes in the Cardiac Proteome (Pending publish) Xin Li, Fatih Arslan, Yan Ren, Sunil S. Adav, Kian Keong Poh, Vitaly Sorokin, Chuen Neng Lee, Dominique De Kleijn, Sai Kiang Lim, Siu Kwan Sze Journal of Proteome Research
25 Apr 2011 BMRC Institute of Medical Biology Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs Soon Sim Tan, Ruenn Chai Lai, Andre Boon Hwa Choo, Jayanthi Padmanabhan, Chuen Neng Lee, Tian Sheng Chen, Fatih Arslan, Yijun Yin, Dominique PV de Kleijn, Sai Kiang Lim Journal of Translational Medicine
11 Feb 2011 BMRC Institute of Medical Biology Derivation and Characterization of Human ESC-Derived Mesenchymal Stem Cells (Pending publish) Mohan Vemuri, Lucas G. Chase, Mahendra S. Rao, Ruenn Chai Lai, Andre Choo, Sai Kiang Lim Methods in Molecular Biology
28 Jan 2011 BMRC Institute of Medical Biology Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction (Pending publish) Andree Choo, Jan J. Piek, Pieter A. Doevendans, Gerard Pasterkamp, Dominique P.V. de Kleijn, Leo Timmers, Sai Kiang Lim, Imo E. Hoefer, Fatih Arslan, Ruenn Chai Lai, Angelique A.M. van Oorschot, Marie Jose Goumans, Chaylendra Strijder, Sui Kwan Sze Stem Cell Research
4 Jan 2010 BMRC Institute of Medical Biology Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury (Pending publish) Chuen Neng Lee, Reida Menshawe El Oakley, Gerard Pasterkamp, Dominique P.V. de Kleijn, Sai Kiang Lim, Ruenn Chai Lai, Fatih Arslan, May May Lee, Newman Siu Kwan Sze, Andre Choo, Tian Sheng Chen, Manuel Salto-Tellez, Leo Timmers Stem Cell Research
25 Aug 2009 BMRC Institute of Medical Biology Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study (Pending publish) Dominique PV de Kleijn, Olivia van Oostrom, Attie Tuinenburg, Sai Kiang Lim, Marianne C Verhaar, Joost O Fledderus, Mario Pescatori, Andrew Stubbs Cardiovascular Diabetology
7 Nov 2008 BMRC Institute of Medical Biology A Comparative Study of Electrostatic Repulsion-Hydrophilic Interaction Chromatography (ERLIC) versus SCX-IMAC-Based Methods for Phosphopeptide Isolation/Enrichment (Pending publish) Chee Sian Gan, Tiannan Guo, Huoming Zhang, Sai Kiang Lim, Siu Kwan Sze Journal of Proteome Research
8 Aug 2008 BMRC Institute of Medical Biology Generating mESC-derived insulin-producing cell lines through an intermediate lineage-restricted progenitor line (Pending publish) Fei Xie, Qizhou Lian, GuoDong Li, Ruihua Luo, Jiping Zhang, Keng Suan Yeo, Eileen Khia Way Tan, Dorothée Caille, Oi Lian Kon, Manuel Salto-Tellez, Paolo Meda, Sai Kiang Lim Stem Cell Research
31 Jul 2008 BMRC Institute of Medical Biology Derivation of functional insulin-producing cell lines from primary mouse embryo culture (Pending publish) Guo Dong Li, Ruihua Luo, Jiping Zhang, Keng Suan Yeo, Fei Xie, Eileen Khia Way Tan, Dorothée Caille, Jianwen Que, Oi Lian Kon, Manuel Salto-Tellez, Paolo Meda, Sai Kiang Lim Stem Cell Research
8 Mar 2008 BMRC Institute of Medical Biology Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium (Pending publish) Leo Timmers, Sai Kiang Lim, Fatih Arslan, Jeffrey S. Armstrong, Imo E. Hoefer, Pieter A. Doevendans, Jan J. Piek, Reida Menshawe El Oakley, Andre Choo, Chuen Neng Lee, Gerard Pasterkamp, Dominique P.V. de Kleijn Stem Cell Research