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6 Sep 2025
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BMRC
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Bioinformatics Institute
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TCM-navigator, a deep learning-based workflow for generation and evaluation of traditional Chinese medicine-like compounds for drug development (Pending publish)
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Feiying Chen,
Victor Jun Yu Lim,
Mingyu Li,
Hao Fan
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Briefings in Bioinformatics
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30 Jul 2025
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BMRC
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Bioinformatics Institute
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A molecular dynamics protocol for rapid prediction of EGFR overactivation and its application to the rare mutations S768I, S768N, D761N (Pending publish)
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Julian Behn,
R.N.V. Krishna Deepak,
Jiancheng Hu,
Hao Fan
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Computational and Structural Biotechnology Journal
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27 Jun 2025
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SERC
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Institute of Microelectronics
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Qubit-State Discrimination using Neural Networks with Rapid and Energy-Efficient Compute Arrays (Pending publish)
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Yuntian Liu,
Yi Sheng Chong,
Benjamin Lienhard,
Minghao Fan,
Wang Ling Goh,
Vishnu P. Nambiar,
Anh Tuan Do
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2025 IEEE International Symposium on Circuits and Systems (ISCAS)
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14 May 2025
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BMRC
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Bioinformatics Institute
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Targeting transcription factors through an IMiD independent zinc finger domain (Pending publish)
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Bee Hui Liu,
Miao Liu,
Sridhar Radhakrishnan,
Meng-Yuan Dai,
Chaitanya Kumar Jaladanki,
Chong Gao,
Jing Ping Tang,
Kalpana Kumari,
Mei Lin Go,
Kim Anh L Vu,
Junsu Kwon,
Hyuk-Soo Seo,
Kijun Song,
Xi Tian,
Li Feng,
Justin L Tan,
Arek V Melkonian,
Zhaoji Liu,
Gerburg Wulf,
Haribabu Arthanari,
Jun Qi,
Sirano Dhe-Paganon,
John G Clohessy,
Yeu Khai Choong,
J Sivaraman,
Hao Fan,
Daniel G Tenen,
Li Chai
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EMBO Molecular Medicine
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5 May 2025
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BMRC
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Bioinformatics Institute
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Unveiling the molecular basis of selective fluorination of SAM-dependent fluorinases (Pending publish)
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Ravi Kumar Verma,
Wan Lin Yeo,
Elaine Tiong,
Ee Lui Ang,
Yee Hwee Lim,
Fong Tian Wong,
Hao Fan
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Chemical Science
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1 Mar 2025
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BMRC
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Bioinformatics Institute
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Identification of Small-Molecule Inhibitors for Enterovirus A71 IRES by Structure-Based Virtual Screening (Pending publish)
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Kaichen Wang,
Sean Xian Yu Lee,
Chaitanya K. Jaladanki,
Wei Shen Ho,
Justin Jang Hann Chu,
Hao Fan,
Christina Li Lin Chai
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Journal of Chemical Information and Modeling
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8 Nov 2024
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SERC
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Institute of Sustainability for Chemicals, Energy and Environment
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A Machine Learning-Guided Approach to Navigate the Substrate Activity Scope of Galactose Oxidase: Application in the Conversion of Pharmaceutically Relevant Bulky Secondary Alcohols
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Shreyas Supekar,
Dillon W. P. Tay,
Wan Lin Yeo,
Kwok Wai Eric Tam,
Ying Sin Koo,
Jie Yang See,
Jhoann M. T. Miyajima,
Sebastian Maurer-Stroh,
Ee Lui Ang,
Yee Hwee Lim,
Hao Fan
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ACS Catalysis
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1 Dec 2023
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BMRC
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Singapore Institute of Food and Biotechnology Innovation
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Directed Evolution and Computational Modeling of Galactose Oxidase toward Bulky Benzylic and Alkyl Secondary Alcohols
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Wan Lin Yeo,
Dillon W. P. Tay,
Jhoann M.T. Miyajima,
Shreyas Supekar,
Tong Mei Teh,
Jin Xu,
Yee Ling Tan,
Jie Yang See,
Hao Fan,
Sebastian Maurer-Stroh,
Yee Hwee Lim,
Ee Lui Ang
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ACS Catalysis
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14 Sep 2023
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BMRC
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Bioinformatics Institute
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Pro-phagocytic function and structural basis of GPR84 signaling
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Xuan Zhang,
Yujing Wang,
Shreyas Supekar,
Xu Cao,
Jingkai Zhou,
Jessica Dang,
Siqi Chen,
Laura Jenkins,
Sara Marsango,
Xiu Li,
Guibing Liu,
Graeme Milligan,
Mingye Feng,
Hao Fan,
Weimin Gong,
Cheng Zhang
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Nature Communications
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20 Feb 2023
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BMRC
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Bioinformatics Institute
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Hepatic mitochondrial NAD+ transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis
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Lili Cheng,
R.N.V. Krishna Deepak,
Guoqiang Wang,
Ziyi Meng,
Lei Tao,
Mengqing Xie,
Wenna Chi,
Yuming Zhang,
Mingming Yang,
Yilie Liao,
Ruiqun Chen,
Yu Liang,
Junyu Zhang,
Yuedong Huang,
Weihua Wang,
Zhiying Guo,
Yunfang Wang,
Jiandie D. Lin,
Hao Fan,
Ligong Chen
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Hepatology
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