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2 Sep 2025
BMRC
Institute of Molecular and Cell Biology
NOX1 and NPY1R mark regional colon stem cell populations that serve as cancer origins in vivo
(Pending publish)
Maxime Gasnier,
Tanysha Chi-Ying Chen,
Swathi Yada,
Sowmya Sagiraju,
Yusuke Yoshikawa,
Stefano Perna,
Hui Yi Grace Lim,
Bernett Lee,
Nick Barker
Nature Cell Biology
22 Aug 2024
BMRC
Institute of Molecular and Cell Biology
Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus
Lana Kostic,
Carly Leung,
Katzrin Ahmad Murad,
Snezhina Kancheva,
Stefano Perna,
Bernett Lee,
Nick Barker
Nature Communications
8 Feb 2024
BMRC
Skin Research Lab
Nanopore Sequencing Enables Allelic Phasing of FLG Loss-of-Function Variants, Intragenic Copy Number Variation, and Methylation Status in Atopic Dermatitis and Ichthyosis Vulgaris
Colin Wong,
Cheng-Yong Tham,
Lin Yang,
Miles C. Benton,
Vipin Narang,
Simon Denil,
Kaibo Duan,
Yik Weng Yew,
Bernett Lee,
Paola Florez de Sessions,
John E.A. Common
Journal of Investigative Dermatology
18 Jan 2024
BMRC
A*STAR Infectious Disease Labs
Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity
Quy Xiao Xuan Lin,
Deepa Rajagopalan,
Akshamal M. Gamage,
Le Min Tan,
Prasanna Nori Venkatesh,
Wharton O. Y. Chan,
Dilip Kumar,
Ragini Agrawal,
Yao Chen,
Siew-Wai Fong,
Amit Singh,
Louisa J. Sun,
Seow-Yen Tan,
Louis Yi Ann Chai,
Jyoti Somani,
Bernett Lee,
Laurent Renia,
Lisa F P Ng,
Kollengode Ramanathan,
Lin-Fa Wang,
Barnaby Young,
David Lye,
Amit Singhal,
Shyam Prabhakar
Nature Communications
28 May 2022
BMRC
Skin Research Lab
Distinct skin microbiome community structures in congenital ichthyosis
Khek‐Chian Tham,
Rachel Lefferdink,
Kaibo Duan,
Seong Soo Lim,
X.F. Colin C. Wong,
Erin Ibler,
Benedict Wu,
Hajar Abu‐Zayed,
Stephanie M. Rangel,
Ester Del Duca,
Mashkura Chowdhury,
Margot Chima,
Hee Jee Kim,
Bernett Lee,
Emma Guttman‐Yassky,
Amy S. Paller,
John E. A. Common
British Journal of Dermatology
26 Jan 2021
BMRC
Institute of Molecular and Cell Biology
A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis
Si Hui Tan,
Phyllis Phuah,
Liang Thing Tan,
Swathi Yada,
Jasmine Goh,
Lucian B. Tomaz,
Magdalene Chua,
Esther Wong,
Bernett Lee,
Nick Barker
Cell Reports
23 Jun 2020
BMRC
Singapore Immunology Network
Combinatorial single-cell analyses of granulocyte-monocyte progenitor heterogeneity reveals an early uni-potent neutrophil progenitor
Immanuel Kwok,
Etienne Becht,
Yu Xia,
Melissa Ng,
Ye Chean Teh,
Leonard De Li Tan,
Maximilien Evrard,
Jackson L.Y Li,
Hoa Tran TN,
Yingrou Tan,
Dehua Liu,
Kahang Liong,
Keith Leong,
Yuning Zhang,
Andre Olsson,
Chinmay Kumar Mantri,
Pavithra Shyamsunder,
Zhaoyuan Liu,
Cecile Piot,
Charles-Antoine Dutertre,
Hui Cheng,
Sudipto Bari,
Nicholas Ang,
Subhra K. Biswas,
H. Philip Koeffler,
Hong Liang Tey,
Anis Larbi,
I-Hsin Su,
Bernett Lee,
Ashley St. John,
Jerry K.Y. Chan,
William Y.K. Hwang,
Jinmiao Chen,
Nathan Salomonis,
Shu Zhen Chong,
H. Leighton Grimes,
Bing Liu,
Andrés Hidalgo,
Evan W. Newell,
Tao Cheng,
Florent Ginhoux,
Lai Guan Ng
Immunity
29 Aug 2019
BMRC
Singapore Immunology Network
Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells
Charles-Antoine Dutertre,
Etienne Becht,
Sergio Erdal Irac,
Ahad Khalilnezhad,
Vipin Narang,
Shabnam Khalilnezhad,
Pei Y. Ng,
Lucas L. van den Hoogen,
Jing Yao Leong,
Bernett Lee,
Marion Chevrier,
Xiao Meng Zhang,
Pearly Ai Yong Jean,
Geraldine Koh,
Josephine Lum,
Shanshan Howland Wu,
Esther Mok,
Jinmiao Chen,
Anis Larbi,
Henry Kun Kiaang Tan,
Tony Kiat Hon Lim,
Panagiota Karagianni,
Athanasios G. Tzioufas,
Benoit Malleret,
Joshua Brody,
Salvatore Albani,
Joel van Roon,
Timothy Radstake,
Evan W. Newell,
Florent Ginhoux
Immunity
27 Aug 2019
BMRC
Institute of Molecular and Cell Biology
RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications
Kai Sen Tan,
Anand Kumar Andiappan,
Bernett Lee,
Yan Yan,
Jing Liu,
See Aik Tang,
Josephine Lum,
Ting Ting He,
Yew Kwang Ong,
Mark Thong,
Hui Fang Lim,
Hyung Won Choi,
Olaf Rotzschke,
Vincent T. Chow,
De Yun Wang
Cells
20 Dec 2018
BMRC
Institute of Molecular and Cell Biology
Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine
David A. G. Skibinski,
Leigh Ann Jones,
Yuan O. Zhu,
Lin Wu Xue,
Bijin Au,
Bernett Lee,
Ahmad Nazri Mohamed Naim,
Audrey Lee,
Nivashini Kaliaperumal,
Jenny G. H. Low,
Lawrence S. Lee,
Michael Poidinger,
Philippe Saudan,
Martin Bachmann,
Eng Eong Ooi,
Brendon J. Hanson,
Veronica Novotny-Diermayr,
Alex Matter,
Anna-Marie Fairhurst,
Martin L. Hibberd,
John E. Connolly
Scientific Reports
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