Applications of Optical Fiber in Label-Free Biosensors and Bioimaging: A Review

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Applications of Optical Fiber in Label-Free Biosensors and Bioimaging: A Review
Title:
Applications of Optical Fiber in Label-Free Biosensors and Bioimaging: A Review
Journal Title:
Biosensors
Publication Date:
30 December 2022
Citation:
Li, B., Zhang, R., Bi, R., & Olivo, M. (2022). Applications of Optical Fiber in Label-Free Biosensors and Bioimaging: A Review. Biosensors, 13(1), 64. https://doi.org/10.3390/bios13010064
Abstract:
Biosensing and bioimaging are essential in understanding biological and pathological processes in a living system, for example, in detecting and understanding certain diseases. Optical fiber has made remarkable contributions to the biosensing and bioimaging areas due to its unique advantages of compact size, immunity to electromagnetic interference, biocompatibility, fast response, etc. This review paper will present an overview of seven common types of optical fiber biosensors and optical fiber-based ultrasound detection in photoacoustic imaging (PAI) and the applications of these technologies in biosensing and bioimaging areas. Of course, there are many types of optical fiber biosensors. Still, this paper will review the most common ones: optical fiber grating, surface plasmon resonance, Sagnac interferometer, Mach–Zehnder interferometer, Michelson interferometer, Fabry–Perot Interferometer, lossy mode resonance, and surface-enhanced Raman scattering. Furthermore, different optical fiber techniques for detecting ultrasound in PAI are summarized. Finally, the main challenges and future development direction are briefly discussed.
License type:
Attribution 4.0 International (CC BY 4.0)
Funding Info:
This research / project is supported by the Agency of Science, Technology and Research (A*STAR) - Industry Alignment Fund prepositioning program (IAF-PP) Award
Grant Reference no. : H19H6a0025

This research / project is supported by the Agency of Science, Technology and Research (A*STAR) - Gap Project
Grant Reference no. : I22AEAG006

This research / project is supported by the Agency of Science, Technology and Research (A*STAR) - BMRC Central Research Fund (UIBR) 2021
Grant Reference no. : NA
Description:
ISSN:
2079-6374
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