Uptake mechanisms of cell-internalizing nucleic acid aptamers for applications as pharmacological agents

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Uptake mechanisms of cell-internalizing nucleic acid aptamers for applications as pharmacological agents
Title:
Uptake mechanisms of cell-internalizing nucleic acid aptamers for applications as pharmacological agents
Other Titles:
RSC Medicinal Chemistry
Publication Date:
24 July 2021
Citation:
Alamudi, S. H., Kimoto, M., & Hirao, I. (2021). Uptake mechanisms of cell-internalizing nucleic acid aptamers for applications as pharmacological agents. RSC Medicinal Chemistry. doi:10.1039/d1md00199j
Abstract:
Selection methods in generating cell-internalizing nucleic acid aptamer via cell-SELEX technique for applications in diagnostics and therapeutics are discussed. Their challenges, optimization strategies and cellular uptake mechanisms are presented.
License type:
Publisher Copyright
Funding Info:
This research / project is supported by the National Research Foundation (NRF) Singapore - Competitive Research Programme
Grant Reference no. : NRF-CRP17-2017-07

This research is supported by core funding from: Institute of Bioengineering and Bioimaging
Grant Reference no. :
Description:
ISSN:
2632-8682
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