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13 Jul 2024
BMRC
Bioinformatics Institute
Exploring bat-inspired cyclic tryptophan diketopiperazines as ABCB1 Inhibitors
Javier Yu Peng Koh,
Yoko Itahana,
Alexander Krah,
Habib Mostafa,
Mingmin Ong,
Sahana Iwamura,
Dona Mariya Vincent,
Sabhashina Radha Krishnan,
Weiying Ye,
Pierre Wing Chi Yim,
Tushar M. Khopade,
Kunihiko Chen,
Pui San Kong,
Lin-Fa Wang,
Roderick W. Bates,
Yasuhisa Kimura,
Rajesh Viswanathan,
Peter J. Bond,
Koji Itahana
Communications Chemistry
15 Feb 2024
BMRC
Bioinformatics Institute
Coarse-Grained Model of Glycosaminoglycans for Biomolecular Simulations
Aishwary T. Shivgan,
Jan K. Marzinek,
Alexander Krah,
Paul Matsudaira,
Chandra S. Verma,
Peter J. Bond
Journal of Chemical Theory and Computation
3 Jan 2024
BMRC
Bioinformatics Institute
High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against nontuberculous mycobacteria in vitro and in vivo
Priya Ragunathan,
Patcharaporn Sae-Lao,
Claire Hamela,
Matthéo Alcaraz,
Alexander Krah,
Wee Han Poh,
Carmen Jia Ern Pee,
Albert Yick Hou Lim,
Scott A. Rice,
Kevin Pethe,
Peter J. Bond,
Thomas Dick,
Laurent Kremer,
Roderick W. Bates,
Gerhard Gruber
Journal of Biological Chemistry
20 Nov 2023
BMRC
Bioinformatics Institute
Variations of the Mycobacterium abscessus F-ATP synthase subunit a-c interface alter binding and potency of the anti-TB drug bedaquiline
Alexander Krah,
Priya Ragunathan,
Peter J. Bond,
Gerhard Gruber
Biochemical and Biophysical Research Communications
10 May 2020
BMRC
Bioinformatics Institute
Extending the Martini coarse-grained forcefield to N-glycans
Aishwary T. Shivgan,
Jan K. Marzinek,
Roland G. Huber,
Alexander Krah,
Richard H. Henchman,
Paul Matsudaira,
Chandra S. Verma,
Peter J. Bond
bioRxiv
3 Mar 2020
BMRC
Bioinformatics Institute
How Ligand Binding Affects the Dynamical Transition Temperature in Proteins
Alexander Krah,
Roland G. Huber,
Peter J. Bond
ChemPhysChem
28 Nov 2019
BMRC
Bioinformatics Institute
On the ion coupling mechanism of the MATE transporter ClbM
Alexander Krah,
Roland G. Huber,
Ulrich Zachariae,
Peter J. Bond
Biochimica et Biophysica Acta (BBA) - Biomembranes
1 Mar 2019
BMRC
Bioinformatics Institute
Insights into water accessible pathways and the inactivation mechanism of proton translocation by the membrane-embedded domain of V-type ATPases
Alexander Krah,
Jan K. Marzinek,
Peter J. Bond
Biochimica et Biophysica Acta (BBA) - Biomembranes
5 Sep 2018
BMRC
Bioinformatics Institute
Single mutations in the ε subunit from thermophilic Bacillus PS3 generate a high binding affinity site for ATP
Alexander Krah,
Peter J. Bond
PeerJ
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